Therapeutic Angiogenesis

2017-07-11 Medical

Author : Yukihito Higashi
Release : 2017-07-11
Genre : Medical
Kind : eBook
Book Rating : 447/5 ( reviews)

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Book Synopsis Therapeutic Angiogenesis by : Yukihito Higashi

Download or read book Therapeutic Angiogenesis written by Yukihito Higashi. This book was released on 2017-07-11. Available in PDF, EPUB and Kindle. Book excerpt: The book discusses recent findings and current perspectives on therapeutic angiogenesis. Studies have shown that therapies such as cell implantation and transfer of gene encoding for angiogenic growth factors are effective in improving symptoms in patients with critical limb ischemia, who previously had no treatment option other than amputation. The book discusses these therapies and presents data collected in clinical studies over the past decade. Despite significant advances in therapeutic angiogenesis since the first clinical studies in the early 21st century, it has been largely ignored in the literature. This comprehensive book fills that gap, making it a valuable resource for both researchers and practitioners alike.

Therapeutic Angiogenesis

1999-09 Medical

Author : J.A. Dormandy
Release : 1999-09
Genre : Medical
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Therapeutic Angiogenesis by : J.A. Dormandy

Download or read book Therapeutic Angiogenesis written by J.A. Dormandy. This book was released on 1999-09. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, rapid progress had been made in elucidating the cellular and molecular mechanisms of new blood vessel formation in both health and disease. Lack of sufficient angiogenesis (new capillary development) and collateral formation (remodeling of existing blood vessels) in adult tissues (e. g. , heart, brain, skeletal muscle) during criti cal ischemia has prompted novel therapeutic strategies to stimulate/fa cilitate angiogenesis and collateral formation in ischemic conditions ("therapeutic angiogenesis"). Therapeutic angiogenesis describes a strategy of inducing new col lateral vessels that can bypass vascular obstructions caused by atherosclerotic disease and stimulating new capillaries that can en hance tissue oxygen exchange. Naturally occurring growth factors (e. g. , FGFs, VEGFs) have been identified and demonstrated to induce new blood vessel formation in the adult organism. The therapeutic ap plication of these growth factors has been demonstrated to enhance these natural processes and have been shown in a number of animal models to increase blood flow and oxygen exchange to ischemic tis sues. Therapeutic angiogenesis therefore represents a new medical principle that is anticipated to be used as an adjunct or alternative to angioplasty and/or bypass surgery. A number of strategies have been proposed and tested to deliver growth factors. One strategy is the direct administration of the growth factor protein by intramuscular, intraarte rial or intravenous delivery.

Arteriogenesis

2006-04-11 Medical

Author : Wolfgang Schaper
Release : 2006-04-11
Genre : Medical
Kind : eBook
Book Rating : 26X/5 ( reviews)

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Book Synopsis Arteriogenesis by : Wolfgang Schaper

Download or read book Arteriogenesis written by Wolfgang Schaper. This book was released on 2006-04-11. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizes the research activities of Germany’s Nauheim Institute of the Max Planck Society and its group of investigators both past and present, in the field of collateral artery growth. Incorporates a multidisciplinary in vivo approach to the study of arteriogenesis that includes molecular approaches with classical physiology and immunohistochemistry. Full color throughout and well illustrated.

Angiogenesis and Direct Myocardial Revascularization

2007-11-05 Medical

Author : Roger J. Laham
Release : 2007-11-05
Genre : Medical
Kind : eBook
Book Rating : 346/5 ( reviews)

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Book Synopsis Angiogenesis and Direct Myocardial Revascularization by : Roger J. Laham

Download or read book Angiogenesis and Direct Myocardial Revascularization written by Roger J. Laham. This book was released on 2007-11-05. Available in PDF, EPUB and Kindle. Book excerpt: An interdisciplinary panel of pioneers and opinion leaders review the basic, preclinical, clinical, and developmental pathways to new treatment strategies, such as therapeutic angiogenesis and myogenesis. The authors take advantage of new biological understanding, novel therapeutic targets, multiple available and well-studied therapeutic strategies, and the necessary imaging techniques to measure outcomes. Their in-depth discussions cover the identification of new therapeutic targets and pathways, the investigation of transcriptional factors, master switch molecules, cell-based approaches, chemokines, a better understanding of the effects of aging, endothelial dysfunction, and hypercholesterolemia in response to angiogenic stimuli. Highlights include examination of drug delivery problems, outcomes measure, stem therapy, high-risk interventions, development pathways, and future possibilities.

Biochemical Basis and Therapeutic Implications of Angiogenesis

2017-08-28 Medical

Author : Jawahar L. Mehta
Release : 2017-08-28
Genre : Medical
Kind : eBook
Book Rating : 151/5 ( reviews)

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Book Synopsis Biochemical Basis and Therapeutic Implications of Angiogenesis by : Jawahar L. Mehta

Download or read book Biochemical Basis and Therapeutic Implications of Angiogenesis written by Jawahar L. Mehta. This book was released on 2017-08-28. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest developments in the therapeutic implications of angiogenesis, ranging from angiogenesis in the brain, angiogenesis in cancer, angiogenesis’ role in atherosclerosis and heart disease as well as metabolic disorders and peripheral vascular disease. The book is comprehensive in its coverage of angiogenesis in a diverse set of diseases and examines the role of cellular and subcellular structures during the development of angiogenesis. Well-organized and thorough, this is an ideal book for researchers and biomedical engineers working in the field of therapeutic implications of angiogenesis. This book also: Covers the basics of the physiology of angiogenesis, including VEGF pathways in angiogenesis, integr ins in angiogenesis, angiogenesis and exercise physiology, and more Details the role of angiogenesis in atherosclerosis and heart disease, including vascular endothelial growth factor and atherosclerotic plaque progression as well as angiogenesis and heart failure Illustrates in detail brain angiogenesis after stroke and the relationship between angiogenesis and Alzheimer's disease

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Therapeutic Angiogenesis

Therapeutic Angiogenesis

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Angiogenesis and Direct Myocardial Revascularization

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