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Pancreatic Beta Cell in Health and Disease

2008-04-08 Science
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Release : 2008-04-08
Genre : Science
Kind : eBook
Book Rating : 520/5 ( reviews)

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Book Synopsis Pancreatic Beta Cell in Health and Disease by : Susumu Seino

Download or read book Pancreatic Beta Cell in Health and Disease written by Susumu Seino. This book was released on 2008-04-08. Available in PDF, EPUB and Kindle. Book excerpt: The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin. This metabolic hormone plays a central role in the maintenance of glucose homeostasis. This book provides a comprehensive review of the beta cell in health and disease. The book’s primary aim is to encourage investigators to become actively involved in diabetes research and the search for new approaches to prevent and treat diabetes.

The Pancreatic Beta Cell

2014-02-20 Medical
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Release : 2014-02-20
Genre : Medical
Kind : eBook
Book Rating : 401/5 ( reviews)

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Book Synopsis The Pancreatic Beta Cell by :

Download or read book The Pancreatic Beta Cell written by . This book was released on 2014-02-20. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on the pancreatic beta cell. Expertise of the contributors Coverage of a vast array of subjects In depth current information at the molecular to the clinical levels Three-dimensional structures in color Elaborate signaling pathways

Control of Pancreatic Beta Cell Function and Plasticity in Health and Diabetes

2016-12-02 Science
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Release : 2016-12-02
Genre : Science
Kind : eBook
Book Rating : 655/5 ( reviews)

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Book Synopsis Control of Pancreatic Beta Cell Function and Plasticity in Health and Diabetes by : David J. Hill

Download or read book Control of Pancreatic Beta Cell Function and Plasticity in Health and Diabetes written by David J. Hill. This book was released on 2016-12-02. Available in PDF, EPUB and Kindle. Book excerpt: Plasticity in insulin-producing cells (β-cells) of the pancreas is a major contributor to metabolic control. Targeted regeneration of pancreatic β-cells for the reversal of diabetes (by optimizing β-cells mass and proliferation to meet metabolic requirements and counter autoimmune response) is still a theoretical intervention. This monograph reviews the biology, ontogeny, capabilities, and present practical limitations of β-cell plasticity. Relevant biochemical pathways are described with the inclusion of information about how they change with aging, during pregnancy, and with diet. Readers will learn the following key aspects about β-cell plasticity: -current knowledge of pancreatic β-cells development, and how β-cell mass and proliferation change throughout the human lifespan -the mechanisms responsible for β-cell plasticity, based on animal models and clinical studies revealing environmental, epigenetic, endocrine and paracrine regulators -the therapeutic potential of resident stem cells within the pancreas / bone marrow and β-cell progenitors This monograph is essential reading for researchers interested in updated knowledge about the molecular and cellular biology of β-cells in the quest to find a reliable therapy for diabetes.

Molecular Basis of Pancreas Development and Function

2012-12-06 Medical
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Release : 2012-12-06
Genre : Medical
Kind : eBook
Book Rating : 692/5 ( reviews)

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Book Synopsis Molecular Basis of Pancreas Development and Function by : Joel F. Habener

Download or read book Molecular Basis of Pancreas Development and Function written by Joel F. Habener. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus is rapidly increasing in prevalence throughout both developed and developing countries. The social and economic burden of this disease is estimated to cost 14 billion dollars worldwide. In the USA alone, 15 million individuals are diabetic, nearly half of them unaware of their condition. Complications of diabetes mellitus are the leading causes for blindness, limb amputation and chronic renal failure and kidney transplantation in industrialized countries. Further, diabetes mellitus per se and the metabolic derangement associated with diabetes are important risk factors for cardiovascular disease. Diabetes, as defined by an elevated fasting blood glucose level is presently subdivided in etiologically distinct groups. The most prevalent being type 2 (adult onset) diabetes characterized by insulin resistance and failure of the ~-cell to supply insulin in amounts sufficient to meet the body's needs. Type 1 (juvenile) diabetes, most commonly with an onset during childhood and adolescence, is caused by an auto-immune destruction of the pancreatic ~-cells. The causations of both type 1 and type 2 diabetes involve a combination of complex genetic traits and environmental influences. A third category are the mature onset diabetes of the young (MODY). This comparatively small group of patients (-10% of diabetes) presents relative early in life «30 years of age) compared to the more common late onset type 2 diabetes.

The Endocrine Pancreas

1991 Medical
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Release : 1991
Genre : Medical
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis The Endocrine Pancreas by : Ellis Samols

Download or read book The Endocrine Pancreas written by Ellis Samols. This book was released on 1991. Available in PDF, EPUB and Kindle. Book excerpt:

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