Share

Glutamate and GABA Receptors and Transporters

2001-10-04 Science
Download Glutamate and GABA Receptors and Transporters PDF Online Free

Author :
Release : 2001-10-04
Genre : Science
Kind : eBook
Book Rating : 818/5 ( reviews)

GET EBOOK


Book Synopsis Glutamate and GABA Receptors and Transporters by : Jan Egebjerg

Download or read book Glutamate and GABA Receptors and Transporters written by Jan Egebjerg. This book was released on 2001-10-04. Available in PDF, EPUB and Kindle. Book excerpt: The ubiquitous presence of glutamate and GABA receptors in the nervous system makes these receptor systems pivotal to our understanding of neurotransmission. Cloning of the molecular components of these receptor systems has provided insights to the selectivity of many drugs and detailed characterisation at the molecular level is emerging. Moreover, continuous development of novel and selective drugs has revealed detailed information on the mechanism of receptor activation and regulation. However, the rapid development of different aspects of glutamate and GABA receptor research makes it increasingly difficult to establish a general view of the field. Studies of the receptors are a multi-disciplinary task employing many specialised techniques. This book conveys recent discoveries in a framework of the basic concepts in the field of glutamate and GABA receptor research. Glutamate and GABA Receptors and Transporters: Structure, Function and Pharmacology is suitable for postgraduate students studying ligand gated channels but also beneficial for industrial and academic research scientists in both the glutamate and GABA field. Universities offering programs in neuroscience, molecular pharmacology or medicinal chemistry will find this a valuable reference.

Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System

2011-08-05 Medical
Download Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System PDF Online Free

Author :
Release : 2011-08-05
Genre : Medical
Kind : eBook
Book Rating : 219/5 ( reviews)

GET EBOOK


Book Synopsis Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System by : Institute of Medicine

Download or read book Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System written by Institute of Medicine. This book was released on 2011-08-05. Available in PDF, EPUB and Kindle. Book excerpt: Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers, or biomarkers, currently exist for measuring glutamate pathology in CNS disorders or injuries. Glutamate dysfunction has been associated with an extensive range of nervous system diseases and disorders. Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer's, substance abuse, and traumatic brain injury. These conditions are widespread, affecting a large portion of the United States population, and remain difficult to treat. Efforts to understand, treat, and prevent glutamate-related disorders can be aided by the identification of valid biomarkers. The Institute of Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop on June 21-22, 2010, to explore ways to accelerate the development, validation, and implementation of such biomarkers. Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System: Workshop Summary investigates promising current and emerging technologies, and outlines strategies to procure resources and tools to advance drug development for associated nervous system disorders. Moreover, this report highlights presentations by expert panelists, and the open panel discussions that occurred during the workshop.

GABA: Receptors, Transporters and Metabolism

2012-12-06 Medical
Download GABA: Receptors, Transporters and Metabolism PDF Online Free

Author :
Release : 2012-12-06
Genre : Medical
Kind : eBook
Book Rating : 909/5 ( reviews)

GET EBOOK


Book Synopsis GABA: Receptors, Transporters and Metabolism by : Chikako Tanaka

Download or read book GABA: Receptors, Transporters and Metabolism written by Chikako Tanaka. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: Highlighting the current developments and future directions in GABA research, the ambitious aim of this topical volume is to cover GABA from the molecular mechanisms of its transmission to new targets for pharmaceutical research. Distinguished scientists at the forefront of GABA research were invited to contribute reviews on glutamate decarboxylase and autoimmunity, molecular structure and functional regulation of GABA transporters, transmitter release and GABA receptor regulation, GABA receptor subtypes and functional regulation, and GABA receptor ligands and their therapeutic application. Describing the latest advances in what has become a rapidly-evolving field, this volume will prove immensely valuable to neuroscientists, pharmacologists, biochemists, and physiologists working in the field of GABA research.

Neurotransmitter Transporters

1996-10-01 Medical
Download Neurotransmitter Transporters PDF Online Free

Author :
Release : 1996-10-01
Genre : Medical
Kind : eBook
Book Rating : 700/5 ( reviews)

GET EBOOK


Book Synopsis Neurotransmitter Transporters by : Maarten E. A. Reith

Download or read book Neurotransmitter Transporters written by Maarten E. A. Reith. This book was released on 1996-10-01. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey of recent advances made in characterizing neurotransmitter transporters-including their imaging in the living brain-and in elucidating the processes underlying biological transport. The expert contributors present up-to-date findings on the molecular cloning of transporters and on neurotransmitter families both in plasma membranes and in storage vesicles. They also provide essential information on the structure-activity relationships for a multitude of recently synthesized dopamine uptake blockers, on transporter changes in the context of human drug abuse, and on the role of transporters in the action of uptake blockers in vivo. The book opens the new frontier of transporters research, authoritatively presenting new insights into their roles in such diseases as brain ischemia and ALS, and into their involvement as targets for antidepressants, antiepileptics, drugs of abuse, and neurotoxins.

GABA And Glutamate

2018-03-21 Medical
Download GABA And Glutamate PDF Online Free

Author :
Release : 2018-03-21
Genre : Medical
Kind : eBook
Book Rating : 219/5 ( reviews)

GET EBOOK


Book Synopsis GABA And Glutamate by : Janko Samardzic

Download or read book GABA And Glutamate written by Janko Samardzic. This book was released on 2018-03-21. Available in PDF, EPUB and Kindle. Book excerpt: This book collates the contributions of a selected number of neuroscientists that are interested in the molecular, preclinical, and clinical aspects of neurotransmission research. The seven chapters in this book address the latest research/review data related to GABA/glutamate system's organization and function, the structure of receptors, subtypes and their ligands, as well as the translational approach and clinical implications. The book offers readers a rich collection of data regarding current and future applications of GABA and glutamate neurotransmission, including promising research strategies and potential clinical benefits.

You may also like...