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Neurotransmitter Transporters

1996-10-01 Medical
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Release : 1996-10-01
Genre : Medical
Kind : eBook
Book Rating : 700/5 ( reviews)

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Book Synopsis Neurotransmitter Transporters by : Maarten E. A. Reith

Download or read book Neurotransmitter Transporters written by Maarten E. A. Reith. This book was released on 1996-10-01. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey of recent advances made in characterizing neurotransmitter transporters-including their imaging in the living brain-and in elucidating the processes underlying biological transport. The expert contributors present up-to-date findings on the molecular cloning of transporters and on neurotransmitter families both in plasma membranes and in storage vesicles. They also provide essential information on the structure-activity relationships for a multitude of recently synthesized dopamine uptake blockers, on transporter changes in the context of human drug abuse, and on the role of transporters in the action of uptake blockers in vivo. The book opens the new frontier of transporters research, authoritatively presenting new insights into their roles in such diseases as brain ischemia and ALS, and into their involvement as targets for antidepressants, antiepileptics, drugs of abuse, and neurotoxins.

Neurotransmitter Release

1999 Medical
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Release : 1999
Genre : Medical
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Neurotransmitter Release by : Hugo J. Bellen

Download or read book Neurotransmitter Release written by Hugo J. Bellen. This book was released on 1999. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with background information on neurotransmitter release. Emphasis is placed on the rationale by which proteins are assigned specific functions rather than just providing facts about function.

Neurotransmitter Transporters

2002 Medical
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Release : 2002
Genre : Medical
Kind : eBook
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Book Synopsis Neurotransmitter Transporters by : Maarten E. A. Reith

Download or read book Neurotransmitter Transporters written by Maarten E. A. Reith. This book was released on 2002. Available in PDF, EPUB and Kindle. Book excerpt: Neurotransmission is a multicomponent process. Transmitters, released by neuronal activity, act on pre- and postsynaptic receptors, and many books detail advances in the receptor field. In addition, after their release from nerve endings, transmitters are removed from the neuronal vicinity by uptake into neuronal or glial cells by specific tra- porter proteins that have been studied intensely over the last 30 years; this information is scattered throughout numerous publishing vehicles. Therefore, the primary aim of this second edition of N- rotransmitter Transporters: Structure, Function, and Regulation is to offer a comprehensive picture of the characterization of neurotransmitter transporters and their biological roles. The transporter field has moved forward in stages. In the first phase, progress came from the use of substrate or blocker ligands selectively targeting transporters, the application of model systems allowing the study of transmitter tra- port shielded from storage, and the development of mathematical models for describing transport phenomena. In the second phase, roughly covering the last decade, advances in DNA techniques allowed the cloning of numerous genes coding for different transporter proteins. In the current, third stage, a wealth of information is being accumulated in studies relating transporter structure with function, experiments addressing regulation by posttranslational transfor- tion, investigations into transport modulation by trafficking processes and genomic influences, characterization of channel properties of tra- porters by electrophysiological approaches, and the creation of transgenic animals under- or overexpressing a given transporter protein.

Neurotransmitter Transporters

1998-09-15 Medical
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Release : 1998-09-15
Genre : Medical
Kind : eBook
Book Rating : 975/5 ( reviews)

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Book Synopsis Neurotransmitter Transporters by : Susan G. Amara

Download or read book Neurotransmitter Transporters written by Susan G. Amara. This book was released on 1998-09-15. Available in PDF, EPUB and Kindle. Book excerpt: General Description of the Series: Neurotransmitter Transporters focuses on biochemical, electrophysiological, pharmacological, molecular, and cell biological approaches used to study neurotransmitter transport systems. The articles provide detailed descriptions of procedures that should enable the reader to understand how they are accomplished and to repeat or adapt them for their own experimental needs. This book is the first to focus on methods that have been the basis for the rapid development of this area. General Description of the Series: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences. Key Features * The transport of CNS neurotransmitter transporters * Electrophysiological, biochemical, molecular, cellular biological, pharmacological, neurochemical, and structural approaches * Both plasma and vesicular carriers

Neurotransmitter Transporters

2006-08-02 Medical
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Release : 2006-08-02
Genre : Medical
Kind : eBook
Book Rating : 847/5 ( reviews)

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Book Synopsis Neurotransmitter Transporters by : Harald Sitte

Download or read book Neurotransmitter Transporters written by Harald Sitte. This book was released on 2006-08-02. Available in PDF, EPUB and Kindle. Book excerpt: This book is a representative survey of the current status of the structure, function, regulation and molecular pharmacology of Neurotransmitter Transporters. It provides an overview of insights generated in the past five years. The volume serves as a useful compendium of current concepts and an inspiring starting point. It is a source for students interested in this emerging field as well as for experienced scientists looking for an update.

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