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Genetic Mapping and DNA Sequencing: Principles, Analysis and Applications

2021-11-16 Science
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Release : 2021-11-16
Genre : Science
Kind : eBook
Book Rating : 464/5 ( reviews)

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Book Synopsis Genetic Mapping and DNA Sequencing: Principles, Analysis and Applications by : Ashton Ward

Download or read book Genetic Mapping and DNA Sequencing: Principles, Analysis and Applications written by Ashton Ward. This book was released on 2021-11-16. Available in PDF, EPUB and Kindle. Book excerpt: Proximate DNA sequences on a chromosome are inherited together during sexual reproduction. This tendency of DNA sequences is called genetic linkage. On a chromosome, the closer two genes are, the higher are their chances of being inherited together and lower are the chances of recombination between them. Gene mapping refers to the set of methods that allow the identification of the locus of a gene as well as the distances between genes. It offers evidences regarding the genes that are responsible for the inheritance of disease from parent to child, and also provides clues regarding the location of the genes and the chromosome where they are located. DNA sequencing is the process that determines the nucleic acid sequence or the order of nucleotides in the DNA. It encompasses all methods that can determine the order of the four bases- thymine, guanine, adenine and cytosine. The development of genetic maps and the successful sequencing of the human genome have advanced the frontiers of genetics and medical science. This book aims to shed light on some of the unexplored aspects of genetic mapping and DNA sequencing and the recent researches in these domains. It includes some of the vital pieces of work being conducted across the world, on various topics related to these fields. This book will prove immensely beneficial to geneticists, genetic engineers, students and researchers associated with these areas of study.

Mapping and Sequencing the Human Genome

1988-01-01 Science
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Release : 1988-01-01
Genre : Science
Kind : eBook
Book Rating : 405/5 ( reviews)

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Book Synopsis Mapping and Sequencing the Human Genome by : National Research Council

Download or read book Mapping and Sequencing the Human Genome written by National Research Council. This book was released on 1988-01-01. Available in PDF, EPUB and Kindle. Book excerpt: There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

DNA Sequencing

2012-04-20 Medical
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Release : 2012-04-20
Genre : Medical
Kind : eBook
Book Rating : 647/5 ( reviews)

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Book Synopsis DNA Sequencing by : Anjana Munshi

Download or read book DNA Sequencing written by Anjana Munshi. This book was released on 2012-04-20. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates methods of DNA sequencing and its application in plant, animal and medical sciences. It has two distinct sections. The one includes 2 chapters devoted to the DNA sequencing methods and the second includes 6 chapters focusing on various applications of this technology. The content of the articles presented in the book is guided by the knowledge and experience of the contributing authors. This book is intended to serve as an important resource and review to the researchers in the field of DNA sequencing.

Principles of Genome Analysis

1998-03-30 Science
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Release : 1998-03-30
Genre : Science
Kind : eBook
Book Rating : 837/5 ( reviews)

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Book Synopsis Principles of Genome Analysis by : Sandy B. Primrose

Download or read book Principles of Genome Analysis written by Sandy B. Primrose. This book was released on 1998-03-30. Available in PDF, EPUB and Kindle. Book excerpt: Genome analysis and genomics are at the forefront of current research in the life sciences. Since the first edition of Principles of Genome Analysis was published, the sequencing of genomes has continued apace, with the major landmark of the human genome sequence being achieved in 2001. Now the emphasis of biological research is on genomics: the understanding of gene function and the interaction of gene products at the whole genome level. As before, this book provides a step-by-step outline of the techniques involved in genome mapping and sequencing. Additionally, the text has been greatly expanded to cover sub-disciplines of genomics, revisions of sections on genome sequencing and bioinformatics, and new chapters on comparative genomics, functional genomics and proteomics. The book concludes with an exciting new chapter describing a variety of ways to utilize genome analysis and sequencing in biology, medicine and agriculture. Aimed at advanced undergraduates, this text will follow the same format as the highly successful Principles of Gene Manipulation by Primrose, Twyman and Old, now in its sixth edition.

Gene Mapping, Discovery, and Expression

2008-02-04 Science
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Release : 2008-02-04
Genre : Science
Kind : eBook
Book Rating : 979/5 ( reviews)

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Book Synopsis Gene Mapping, Discovery, and Expression by : Minou Bina

Download or read book Gene Mapping, Discovery, and Expression written by Minou Bina. This book was released on 2008-02-04. Available in PDF, EPUB and Kindle. Book excerpt: Completion of the sequence of the human genome represents an unpar- leled achievement in the history of biology. The project has produced nearly complete, highly accurate, and comprehensive sequences of genomes of s- eral organisms including human, mouse, drosophila, and yeast. Furthermore, the development of high-throughput technologies has led to an explosion of projects to sequence the genomes of additional organisms including rat, chimp, dog, bee, chicken, and the list is expanding. The nearly completed draft of genomic sequences from numerous species has opened a new era of research in biology and in biomedical sciences. In keeping with the interdisciplinary nature of the new scientific era, the chapters in Gene Mapping, Discovery, and Expression: Methods and Protocols recapitulate the necessity of integration of experimental and computational tools for solving - portant research problems. The general underlying theme of this volume is DNA sequence-based technologies. At one level, the book highlights the importance of databases, genome-browsers, and web-based tools for data access and ana- sis. More specifically, sequencing projects routinely deposit their data in p- licly available databases including GenBank, at the National Center of Biotechnology (NCBI) in the United States; EMBL, maintained by the European Bioinformatics Institute; and DDBJ, the DNA Data Bank of Japan. Currently, several browsers offer facile access to numerous genomic DNA sequences for gene mapping and data retrieval.

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