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Using CNS Autopsy Tissue in Psychiatric Research: A Practical Guide

2019-02-13 Medical
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Release : 2019-02-13
Genre : Medical
Kind : eBook
Book Rating : 417/5 ( reviews)

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Book Synopsis Using CNS Autopsy Tissue in Psychiatric Research: A Practical Guide by : Brian Dean

Download or read book Using CNS Autopsy Tissue in Psychiatric Research: A Practical Guide written by Brian Dean. This book was released on 2019-02-13. Available in PDF, EPUB and Kindle. Book excerpt: Essential for the laboratory, this practical manual presents a wide variety of techniques associated with the use of human CNS tissue obtained at autopsy. The book contains detailed methodologies in discrete chapters written by an expert in the specific field. It also addresses the potential for extending molecular studies in brain tissue obtain

Using CNS Autopsy Tissue in Psychiatric Research

1999 Neuropsychiatry
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Release : 1999
Genre : Neuropsychiatry
Kind : eBook
Book Rating : 243/5 ( reviews)

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Book Synopsis Using CNS Autopsy Tissue in Psychiatric Research by : Brian Dean

Download or read book Using CNS Autopsy Tissue in Psychiatric Research written by Brian Dean. This book was released on 1999. Available in PDF, EPUB and Kindle. Book excerpt: Essential for the laboratory, this practical manual presents a wide variety of techniques associated with the use of human CNS tissue obtained at autopsy. The book contains detailed methodologies in discrete chapters written by an expert in the specific field. It also addresses the potential for extending molecular studies in brain tissue obtained at autopsy into studies in living brain by using neuroimaging techniques. In addition, the reader is directed to suppliers of equipment and reagents that have been shown to be useful when studying human brain tissue.

The Postmortem Brain in Psychiatric Research

2013-03-09 Psychology
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Release : 2013-03-09
Genre : Psychology
Kind : eBook
Book Rating : 312/5 ( reviews)

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Book Synopsis The Postmortem Brain in Psychiatric Research by : Galila Agam

Download or read book The Postmortem Brain in Psychiatric Research written by Galila Agam. This book was released on 2013-03-09. Available in PDF, EPUB and Kindle. Book excerpt: Because of the dearth of experimental animal models of psychiatric disorders, the study of the effect of the disease state is only possible in tissue derived from patients vs. controls, especially in the target tissue of disease-related changes in the brain. The human postmortem brain offers the most appropriate experimental paradigm towards understanding the etiology of psychiatric disorders. The availability of post-mortem human samples from psychiatric patients and comparison groups in recent years has contributed prominently to the accumulating body of information leading to a better understanding of these disorders. This is the first book to summarize this research approach and the meaningful data which has recently been acquired.

Brain Banking

2018-02-27 Medical
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Release : 2018-02-27
Genre : Medical
Kind : eBook
Book Rating : 420/5 ( reviews)

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Book Synopsis Brain Banking by :

Download or read book Brain Banking written by . This book was released on 2018-02-27. Available in PDF, EPUB and Kindle. Book excerpt: Brain Banking, Volume 150, serves as the only book on the market offering comprehensive coverage of the functional realities of brain banking. It focuses on brain donor recruitment strategies, brain bank networks, ethical issues, brain dissection/tissue processing/tissue dissemination, neuropathological diagnosis, brain donor data, and techniques in brain tissue analysis. In accordance with massive initiatives, such as BRAIN and the EU Human Brain Project, abnormalities and potential therapeutic targets of neurological and psychiatric disorders need to be validated in human brain tissue, thus requiring substantial numbers of well characterized human brains of high tissue quality with neurological and psychiatric diseases. - Offers comprehensive coverage of the functional realities of brain banking, with a focus on brain donor recruitment strategies, brain bank networks, ethical issues, and more - Serves as a valuable resource for staff in existing brain banks by highlighting best practices - Enhances the sharing of expertise between existing banks and highlights a range of techniques applicable to banked tissue for neuroscience researchers - Authored by leaders from brain banks around the globe – the broadest, most expert coverage available

Functional Genomics and Proteomics in the Clinical Neurosciences

2006-10-09 Science
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Release : 2006-10-09
Genre : Science
Kind : eBook
Book Rating : 633/5 ( reviews)

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Book Synopsis Functional Genomics and Proteomics in the Clinical Neurosciences by : Scott E. Hemby

Download or read book Functional Genomics and Proteomics in the Clinical Neurosciences written by Scott E. Hemby. This book was released on 2006-10-09. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this work is to familiarize neuroscientists with the available tools for proteome research and their relative abilities and limitations. To know the identities of the thousands of different proteins in a cell, and the modifications to these proteins, along with how the amounts of both of these change in different conditions would revolutionize biology and medicine. While important strides are being made towards achieving the goal of global mRNA analysis, mRNA is not the functional endpoint of gene expression and mRNA expression may not directly equate with protein expression. There are many potential applications for proteomics in neuroscience: determination of the neuro-proteome, comparative protein expression profiling, post-translational protein modification profiling and mapping protein-protein interactions, to name but a few. Functional Genomics and Proteomics in Clinical Neuroscience will comment on all of these applications, but with an emphasis on protein expression profiling. This book combines the basic methodology of genomics and proteomics with the current applications of such technologies in understanding psychiatric illnesses.* Introduction of basic methodologies in genomics and proteomics and their integration in psychiatry* Development of the text in sections related to methods, application and future directions of these rapidly advancing technologies* Use of actual data to illustrate many principles of functional genomics and proteomics. * Introduction to bioinformatics and database management techniques

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