1# Library to Find Best eBook for Read
Author : Bernard Louis Strehler
Release : 1962
Genre : Aging
Kind : eBook
Book Rating : /5 ( reviews)
Book Synopsis Time, Cells, and Aging by : Bernard Louis Strehler
Download or read book Time, Cells, and Aging written by Bernard Louis Strehler. This book was released on 1962. Available in PDF, EPUB and Kindle. Book excerpt: Zelle / Alter.
Author : Bernard Strihler
Release : 2012-12-02
Genre : Science
Kind : eBook
Book Rating : 693/5 ( reviews)
Book Synopsis Times, Cells, and Aging by : Bernard Strihler
Download or read book Times, Cells, and Aging written by Bernard Strihler. This book was released on 2012-12-02. Available in PDF, EPUB and Kindle. Book excerpt: Time, Cells, and Aging, 2nd Edition presents the mechanics of cell function and the relevant implications of the molecular-genetic view to the aging phenomena. This book explores the biology of the aging process. Comprised of 11 chapters, this edition starts with an overview of the causes and mechanisms underlying the gradual deterioration of structure and function characteristics of aging. This text then examines the two aspects of the behavior of man, including the reasoned conscious behavior and the greater dependence on reaction patterns predicted on the successful responses of the past. Other chapters explore the relationship between aging and mortality rate in animals, which is a result of an organism’s deceasing ability to function optimally in carrying out his vital functions. The final chapter deals with the implementation of a research plan relevant to understanding the primary mechanisms of the aging process. This book is a valuable resource for gerontologists, biologists, and molecular biologists.
Author : Surajit Pathak
Release : 2021-03-17
Genre : Science
Kind : eBook
Book Rating : 133/5 ( reviews)
Book Synopsis Stem Cells and Aging by : Surajit Pathak
Download or read book Stem Cells and Aging written by Surajit Pathak. This book was released on 2021-03-17. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cells and Aging covers what is known about the effect of time and age on the basic units of life, which are the corresponding tissue-specific or adult stem cells. Even though the concept of stem cells was introduced nearly a century ago by Alexander Maximow, modern stem-cell research began in 1963 when James Till, Ernest McCullough and Lou Siminovitch established assays to detect hematopoietic stem cells. In fact, given the importance of the aging-associated diseases, scientists have developed a keen interest in understanding the aging process as they attempt to define the role of dysfunctional stem cells in the aging process. With an aging population worldwide, understanding these age-related stem cell changes at a basic biology level and at the level of their influences for regenerative medicine is of interest and importance. There is increasing evidence that the aging process can have much adverse effects on stem cells. In the modern era, one of the emerging fields in treating human diseases is stem cell research, as stem cells have the remarkable potential to treat a wide range of diseases. Nevertheless, understanding the molecular mechanism involved in aging and deterioration of stem cell function is crucial in developing effective new therapies for aging. Serves as an ideal reference to guide investigators toward valuable answers to the problems of our aging population Addresses the effect of time and age on human stem cells Includes chapters from contributors exploring the biology of stem cell aging around the globe
Author : Trygve O. Tollefsbol
Release : 2009-11-11
Genre : Medical
Kind : eBook
Book Rating : 398/5 ( reviews)
Book Synopsis Epigenetics of Aging by : Trygve O. Tollefsbol
Download or read book Epigenetics of Aging written by Trygve O. Tollefsbol. This book was released on 2009-11-11. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.
Author : David A. Sinclair
Release : 2019-09-10
Genre : Science
Kind : eBook
Book Rating : 977/5 ( reviews)
Book Synopsis Lifespan by : David A. Sinclair
Download or read book Lifespan written by David A. Sinclair. This book was released on 2019-09-10. Available in PDF, EPUB and Kindle. Book excerpt: A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.” —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people. It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.” This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger. Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.
