Stem Cells and Aging

2021-03-17 Science

Author : Surajit Pathak
Release : 2021-03-17
Genre : Science
Kind : eBook
Book Rating : 133/5 ( reviews)

GET EBOOK

Book Synopsis Stem Cells and Aging by : Surajit Pathak

Download or read book Stem Cells and Aging written by Surajit Pathak. This book was released on 2021-03-17. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cells and Aging covers what is known about the effect of time and age on the basic units of life, which are the corresponding tissue-specific or adult stem cells. Even though the concept of stem cells was introduced nearly a century ago by Alexander Maximow, modern stem-cell research began in 1963 when James Till, Ernest McCullough and Lou Siminovitch established assays to detect hematopoietic stem cells. In fact, given the importance of the aging-associated diseases, scientists have developed a keen interest in understanding the aging process as they attempt to define the role of dysfunctional stem cells in the aging process. With an aging population worldwide, understanding these age-related stem cell changes at a basic biology level and at the level of their influences for regenerative medicine is of interest and importance. There is increasing evidence that the aging process can have much adverse effects on stem cells. In the modern era, one of the emerging fields in treating human diseases is stem cell research, as stem cells have the remarkable potential to treat a wide range of diseases. Nevertheless, understanding the molecular mechanism involved in aging and deterioration of stem cell function is crucial in developing effective new therapies for aging. Serves as an ideal reference to guide investigators toward valuable answers to the problems of our aging population Addresses the effect of time and age on human stem cells Includes chapters from contributors exploring the biology of stem cell aging around the globe

Stem Cell Aging: Mechanisms, Consequences, Rejuvenation

2015-07-06 Science

Author : Hartmut Geiger
Release : 2015-07-06
Genre : Science
Kind : eBook
Book Rating : 32X/5 ( reviews)

GET EBOOK

Book Synopsis Stem Cell Aging: Mechanisms, Consequences, Rejuvenation by : Hartmut Geiger

Download or read book Stem Cell Aging: Mechanisms, Consequences, Rejuvenation written by Hartmut Geiger. This book was released on 2015-07-06. Available in PDF, EPUB and Kindle. Book excerpt: Aging of somatic stem cells reduces cell function and results in dysfunctional organs and tissues, making it an underlying cause of diseases associated with aging. It might even be the primary cause for age-associated attrition of tissue function in organs that heavily rely on stem cells for maintaining homeostasis, like the skin, blood and intestines. Understanding the molecular and cellular mechanisms involved is critical for developing approaches to attenuate stem cell aging and could pave the way for improved quality of life among the elderly. Written by highly prominent experts in the field, this book presents the current state of knowledge on these mechanisms. It offers insights into stem cell function, explains in detail the mechanisms of stem cell aging in model organisms as well as mammalian systems and describes related diseases and approaches to attenuating stem cell aging or achieving rejuvenation. The book is intended for all scientists and clinicians working with stem cells, aging mechanisms or age-related diseases.

Adult Stem Cells in Aging, Diseases and Cancer

2014-12-22 Medical

Author : K.L. Rudolph
Release : 2014-12-22
Genre : Medical
Kind : eBook
Book Rating : 324/5 ( reviews)

GET EBOOK

Book Synopsis Adult Stem Cells in Aging, Diseases and Cancer by : K.L. Rudolph

Download or read book Adult Stem Cells in Aging, Diseases and Cancer written by K.L. Rudolph. This book was released on 2014-12-22. Available in PDF, EPUB and Kindle. Book excerpt: The functionality of adult tissue stem cells from various organ systems declines during aging. This publication summarizes novel molecular mechanisms responsible for the development of aging-associated deficiencies as discussed by leading experts during the 5th Else Kröner-Fresenius Symposium. It is the first book that explicitly focuses on molecular mechanisms of stem cell aging and its consequences for disease and cancer development including both cell-intrinsic mechanisms as well as aging-induced alterations in the stem cell niche and the systemic environment. Cutting-edge information on stem cells, aging, cancer, and disease make this publication of special interest to basic researchers in the respective fields. Further, it is also intended for medical doctors in the fields of geriatrics, internal medicine, and cancer as it provides a novel understanding of the evolution of tissue dysfunction, diseases and cancer as a consequence of aging.

Advances in Stem Cell Aging

2012 Medical

Author : K. Lenhard Rudolph
Release : 2012
Genre : Medical
Kind : eBook
Book Rating : 709/5 ( reviews)

GET EBOOK

Book Synopsis Advances in Stem Cell Aging by : K. Lenhard Rudolph

Download or read book Advances in Stem Cell Aging written by K. Lenhard Rudolph. This book was released on 2012. Available in PDF, EPUB and Kindle. Book excerpt: Up-to-date meeting report of the Else Kr ner-Fresenius Symposium on Adult Stem Cell Aging Adult stem cells are present in most postnatal tissues of mammals. Tissues with high rates of cell turnover depend on the functional capacity of stem cells for lifelong maintenance of tissue homeostasis. Adult stem cells are also required for the regeneration of tissues in response to injury as in, for example, the regeneration of skeletal muscle. In addition to its function in tissue homeostasis and regeneration, adult stem cells can represent the cell type of origin of various types of cancers including leukemia and colorectal cancer. Stem cells are the most long-lived cells in the proliferative compartment of mammalian tissues. Therefore, stem cells have an increased risk of acquiring mutations that could ultimately lead to the transformation of tissue stem cells. This publication presents the current knowledge in the field of stem cell aging, which was discussed at the Else Kr ner-Fresenius Symposium on Advances in Stem Cell Aging in 2011. It will be of special interest to scientists working on stem cell research, aging, regeneration, and cancer as well as physicians and scientists specializing in geriatric medicine, internal medicine, and surgery.

The Stem Cell Niche during Ageing

2020-08-22 Science

Author : Susie Nilsson
Release : 2020-08-22
Genre : Science
Kind : eBook
Book Rating : 201/5 ( reviews)

GET EBOOK

Book Synopsis The Stem Cell Niche during Ageing by : Susie Nilsson

Download or read book The Stem Cell Niche during Ageing written by Susie Nilsson. This book was released on 2020-08-22. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Stem Cells and Their Niches addresses stem cells during development, homeostasis, and disease/injury of the respective organs, presenting new developments in the field, including new data on disease and clinical applications. Video content illustrates such areas as protocols, transplantation techniques, and work with mice. Explores not only reviews of research, but also shares methods, protocols, and transplantation techniques Contains video content to illustrate such areas as protocols, transplantation techniques, and work with mice Each volume concentrates on one organ, making this a unique publication

Popular eBooks

Stem Cells and Aging

Stem Cell Aging: Mechanisms, Consequences, Rejuvenation

Adult Stem Cells in Aging, Diseases and Cancer

Advances in Stem Cell Aging

The Stem Cell Niche during Ageing

You may also like...