Therapeutic Applications of Adenoviruses

2016-12-12 Medical

Author : Philip Ng
Release : 2016-12-12
Genre : Medical
Kind : eBook
Book Rating : 803/5 ( reviews)

Book Synopsis Therapeutic Applications of Adenoviruses by : Philip Ng

Download or read book Therapeutic Applications of Adenoviruses written by Philip Ng. This book was released on 2016-12-12. Available in PDF, EPUB and Kindle. Book excerpt: Adenoviruses are double stranded DNA viruses that have been used to study the process of DNA replication. Studies of the mode of action of adenovirally produced tumors in rodents led to the discovery of tumour supressor genes. The adenoviral vector is now the most used vector in clinical gene therapy especially for some kinds of cancers. The chapters in this book focus on the most up-to-date developments in the therapeutic applications of adenoviruses. The intended audience is individuals in the Life Sciences interested in therapeutic applications of adenoviruses. This book reviews the life history and immune responses to adenoviruses and summarizes various therapies implemented with the use of adenoviruses.

Adenoviral Vectors for Gene Therapy

2016-03-10 Science

Author : David T. Curiel
Release : 2016-03-10
Genre : Science
Kind : eBook
Book Rating : 106/5 ( reviews)

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Book Synopsis Adenoviral Vectors for Gene Therapy by : David T. Curiel

Download or read book Adenoviral Vectors for Gene Therapy written by David T. Curiel. This book was released on 2016-03-10. Available in PDF, EPUB and Kindle. Book excerpt: Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models, with final consideration of the regulatory issues surrounding human clinical gene therapy trials. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors. Provides complete coverage of the basic biology of adenoviruses, as well as their construction, propagation, and purification of adenoviral vectors Introduces common strategies for the development of adenoviral vectors, along with cutting-edge methods for their improvement Demonstrates noninvasive imaging of adenovirus-mediated gene transfer Discusses utility of adenoviral vectors in animal disease models Considers Federal Drug Administration regulations for human clinical trials

Immunopharmacology

2008-12-19 Medical

Author : Manzoor M. Khan
Release : 2008-12-19
Genre : Medical
Kind : eBook
Book Rating : 760/5 ( reviews)

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Book Synopsis Immunopharmacology by : Manzoor M. Khan

Download or read book Immunopharmacology written by Manzoor M. Khan. This book was released on 2008-12-19. Available in PDF, EPUB and Kindle. Book excerpt: During the past decades, with the introduction of the recombinant DNA, hybridoma and transgenic technologies there has been an exponential evolution in understanding the pathogenesis, diagnosis and treatment of a large number of human diseases. The technologies are evident with the development of cytokines and monoclonal antibodies as therapeutic agents and the techniques used in gene therapy. Immunopharmacology is that area of biomedical sciences where immunology, pharmacology and pathology overlap. It concerns the pharmacological approach to the immune response in physiological as well as pathological events. This goals and objectives of this textbook are to emphasize the developments in immunology and pharmacology as they relate to the modulation of immune response. The information includes the pharmacology of cytokines, monoclonal antibodies, mechanism of action of immune-suppressive agents and their relevance in tissue transplantation, therapeutic strategies for the treatment of AIDS and the techniques employed in gene therapy. The book is intended for health care professional students and graduate students in pharmacology and immunology.

Novel Technologies for Vaccine Development

2014-11-13 Medical

Author : Igor S Lukashevich
Release : 2014-11-13
Genre : Medical
Kind : eBook
Book Rating : 182/5 ( reviews)

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Book Synopsis Novel Technologies for Vaccine Development by : Igor S Lukashevich

Download or read book Novel Technologies for Vaccine Development written by Igor S Lukashevich. This book was released on 2014-11-13. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a detailed overview of the development of new viral vector-based vaccines before discussing two major applications: preventive vaccines for infectious diseases and therapeutic cancer vaccines. Viral vector-based vaccines hold a great potential for development into successful pharmaceutical products and several examples at the advanced pre-clinical or clinical stage are presented. Nevertheless, the most efforts were focused on novel and very innovative technologies for new generation of vector-based vaccines. Furthermore, specific topics such as delivery and adjuvant and protection strategies for cell-mediated-based vaccines are presented. Given its scope, the book is a “must read” for all those involved in vaccine development, both in academia and industrial vaccine development.

Human Adenoviruses

2016 SCIENCE

Author : S. Jane Flint
Release : 2016
Genre : SCIENCE
Kind : eBook
Book Rating : 803/5 ( reviews)

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Book Synopsis Human Adenoviruses by : S. Jane Flint

Download or read book Human Adenoviruses written by S. Jane Flint. This book was released on 2016. Available in PDF, EPUB and Kindle. Book excerpt:

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Therapeutic Applications of Adenoviruses

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Immunopharmacology

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