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The Adenoviruses

2013-03-08 Medical
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Release : 2013-03-08
Genre : Medical
Kind : eBook
Book Rating : 350/5 ( reviews)

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Book Synopsis The Adenoviruses by : Harold S. Ginsberg

Download or read book The Adenoviruses written by Harold S. Ginsberg. This book was released on 2013-03-08. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of adenoviruses naturally induced a new interest in viruses of the human upper respiratory tract since previously unknown viruses infecting this portion of the human body had not been identified in 20 years, and their unique characteristics stimulated investigations into the biochemical events essential for replication of animal viruses. Indeed, the field of molecular virology has evolved during the period since their dis covery, and adenoviruses have played a major role in this development. The exciting discoveries made with adenoviruses have had such a pro found effect on knowledge in basic virology, molecular biology, viral ge netics, human and animal infections, and cell transformation that this seemed a propitious time to have some of the major contributors review this field. This volume pays tribute to the late Wallace Rowe, Robert Huebner, and Maurice Hilleman whose initial discoveries of adenoviruses have tremendously enriched virology. Harold S. Ginsberg vii Contents Chapter 1 An Overview 1 Harold S. Ginsberg Chapter 2 The Architecture of Adenoviruses M. V. Nermut I. Introduction ................................... . 5 II. Chemical and Physical Properties ................... . 6 III. Virus Capsid: Composition and Organization .......... . 7 A. Hexon ..................................... . 10 B. Penton .................................... . 12 C. Other Virus Polypeptides Associated with the Capsid 13 D. Organization of the Capsid ..................... . 14 IV. Virus Core .................................... . 15 A. Evidence for the Core Shell ..................... . 17 B. Organization of the DNA-Protein Complex (Nucleoc- sid) ....................................... . 18 C. Tentative Model of the Adenovirus Nucleocapsid ... . 22 V. Model of the Adenovirion ......................... . 29 32 References .......................................... .

Human Adenoviruses: From Villains To Vectors

2016-12-21 Science
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Release : 2016-12-21
Genre : Science
Kind : eBook
Book Rating : 815/5 ( reviews)

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Book Synopsis Human Adenoviruses: From Villains To Vectors by : S Jane Flint

Download or read book Human Adenoviruses: From Villains To Vectors written by S Jane Flint. This book was released on 2016-12-21. Available in PDF, EPUB and Kindle. Book excerpt: Human adenoviruses play a central role in human diseases and as vectors for vaccines and gene delivery. This monograph describes the underlying principles of adenovirus molecular and structural biology, pathogenesis, antiviral measures and vector development. Much of the history of this virus and the many contributions made by its study are embedded in these discussions. Topics and questions that require further investigation are also considered.Although current virology textbooks cover topics related to adenoviruses, this book provides a comprehensive description of the virus and its interactions with the host. Students and researchers with a particular interest in adenoviruses, gene therapists, and virologists interested in viral pathogenesis will benefit from this book, which presents a unique integration of the basics with applied research in the field.

Adenoviral Vectors for Gene Therapy

2016-03-10 Science
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Release : 2016-03-10
Genre : Science
Kind : eBook
Book Rating : 106/5 ( reviews)

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Book Synopsis Adenoviral Vectors for Gene Therapy by : David T. Curiel

Download or read book Adenoviral Vectors for Gene Therapy written by David T. Curiel. This book was released on 2016-03-10. Available in PDF, EPUB and Kindle. Book excerpt: Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models, with final consideration of the regulatory issues surrounding human clinical gene therapy trials. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors. Provides complete coverage of the basic biology of adenoviruses, as well as their construction, propagation, and purification of adenoviral vectors Introduces common strategies for the development of adenoviral vectors, along with cutting-edge methods for their improvement Demonstrates noninvasive imaging of adenovirus-mediated gene transfer Discusses utility of adenoviral vectors in animal disease models Considers Federal Drug Administration regulations for human clinical trials

Adenoviruses

2019-03-13 Science
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Release : 2019-03-13
Genre : Science
Kind : eBook
Book Rating : 90X/5 ( reviews)

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Book Synopsis Adenoviruses by : Yulia Desheva

Download or read book Adenoviruses written by Yulia Desheva. This book was released on 2019-03-13. Available in PDF, EPUB and Kindle. Book excerpt: Adenoviruses are among the most studied and at the same time most mysterious of viruses. In this book, the authors highlight the achievements in the study of animal and human adenoviruses, chemotherapy of adenovirus infections, and the development in adenoviral vector-based vaccines and gene therapy. I believe that this book will be useful not only for researchers but also in solving specific medical problems.

Human Adenoviruses: New Insights for the Healthcare Professional: 2011 Edition

2012-01-09 Medical
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Release : 2012-01-09
Genre : Medical
Kind : eBook
Book Rating : 629/5 ( reviews)

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Book Synopsis Human Adenoviruses: New Insights for the Healthcare Professional: 2011 Edition by :

Download or read book Human Adenoviruses: New Insights for the Healthcare Professional: 2011 Edition written by . This book was released on 2012-01-09. Available in PDF, EPUB and Kindle. Book excerpt: Human Adenoviruses: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Human Adenoviruses in a compact format. The editors have built Human Adenoviruses: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Human Adenoviruses in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Human Adenoviruses: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

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