Share

The Adenoviruses

2013-03-08 Medical
Download The Adenoviruses PDF Online Free

Author :
Release : 2013-03-08
Genre : Medical
Kind : eBook
Book Rating : 350/5 ( reviews)

GET EBOOK


Book Synopsis The Adenoviruses by : Harold S. Ginsberg

Download or read book The Adenoviruses written by Harold S. Ginsberg. This book was released on 2013-03-08. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of adenoviruses naturally induced a new interest in viruses of the human upper respiratory tract since previously unknown viruses infecting this portion of the human body had not been identified in 20 years, and their unique characteristics stimulated investigations into the biochemical events essential for replication of animal viruses. Indeed, the field of molecular virology has evolved during the period since their dis covery, and adenoviruses have played a major role in this development. The exciting discoveries made with adenoviruses have had such a pro found effect on knowledge in basic virology, molecular biology, viral ge netics, human and animal infections, and cell transformation that this seemed a propitious time to have some of the major contributors review this field. This volume pays tribute to the late Wallace Rowe, Robert Huebner, and Maurice Hilleman whose initial discoveries of adenoviruses have tremendously enriched virology. Harold S. Ginsberg vii Contents Chapter 1 An Overview 1 Harold S. Ginsberg Chapter 2 The Architecture of Adenoviruses M. V. Nermut I. Introduction ................................... . 5 II. Chemical and Physical Properties ................... . 6 III. Virus Capsid: Composition and Organization .......... . 7 A. Hexon ..................................... . 10 B. Penton .................................... . 12 C. Other Virus Polypeptides Associated with the Capsid 13 D. Organization of the Capsid ..................... . 14 IV. Virus Core .................................... . 15 A. Evidence for the Core Shell ..................... . 17 B. Organization of the DNA-Protein Complex (Nucleoc- sid) ....................................... . 18 C. Tentative Model of the Adenovirus Nucleocapsid ... . 22 V. Model of the Adenovirion ......................... . 29 32 References .......................................... .

Therapeutic Applications of Adenoviruses

2016-12-12 Medical
Download Therapeutic Applications of Adenoviruses PDF Online Free

Author :
Release : 2016-12-12
Genre : Medical
Kind : eBook
Book Rating : 803/5 ( reviews)

GET EBOOK


Book Synopsis Therapeutic Applications of Adenoviruses by : Philip Ng

Download or read book Therapeutic Applications of Adenoviruses written by Philip Ng. This book was released on 2016-12-12. Available in PDF, EPUB and Kindle. Book excerpt: Adenoviruses are double stranded DNA viruses that have been used to study the process of DNA replication. Studies of the mode of action of adenovirally produced tumors in rodents led to the discovery of tumour supressor genes. The adenoviral vector is now the most used vector in clinical gene therapy especially for some kinds of cancers. The chapters in this book focus on the most up-to-date developments in the therapeutic applications of adenoviruses. The intended audience is individuals in the Life Sciences interested in therapeutic applications of adenoviruses. This book reviews the life history and immune responses to adenoviruses and summarizes various therapies implemented with the use of adenoviruses.

Adenoviral Vectors for Gene Therapy

2016-03-10 Science
Download Adenoviral Vectors for Gene Therapy PDF Online Free

Author :
Release : 2016-03-10
Genre : Science
Kind : eBook
Book Rating : 106/5 ( reviews)

GET EBOOK


Book Synopsis Adenoviral Vectors for Gene Therapy by : David T. Curiel

Download or read book Adenoviral Vectors for Gene Therapy written by David T. Curiel. This book was released on 2016-03-10. Available in PDF, EPUB and Kindle. Book excerpt: Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models, with final consideration of the regulatory issues surrounding human clinical gene therapy trials. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors. Provides complete coverage of the basic biology of adenoviruses, as well as their construction, propagation, and purification of adenoviral vectors Introduces common strategies for the development of adenoviral vectors, along with cutting-edge methods for their improvement Demonstrates noninvasive imaging of adenovirus-mediated gene transfer Discusses utility of adenoviral vectors in animal disease models Considers Federal Drug Administration regulations for human clinical trials

Viral Infections of Humans

2013-11-11 Medical
Download Viral Infections of Humans PDF Online Free

Author :
Release : 2013-11-11
Genre : Medical
Kind : eBook
Book Rating : 270/5 ( reviews)

GET EBOOK


Book Synopsis Viral Infections of Humans by : Alfred S. Evans

Download or read book Viral Infections of Humans written by Alfred S. Evans. This book was released on 2013-11-11. Available in PDF, EPUB and Kindle. Book excerpt: also occurs. New outbreaks of yellow fever have occurred in Colombia and Trinidad and new outbreaks of rift valley fever have occurred in Egypt. Chapter 6, Arenaviruses: The biochemical and physical properties have now been clar ified, and they show a remarkable uniformity in the various viruses constituting the group. The possibility that prenatal infection with LCM may result in hydrocephalus and chorioretinitis has been raised. Serologic surveys have suggested the existence of Lassa virus infection in Guinea, Central African Empire, Mali, Senegal, Cameroon, and Benin, in addition to earlier identification in Nigeria, Liberia, and Sierra Leone. Chapter 7, Coronaviruses: New studies have confirmed the important role of these viruses in common respiratory illnesses of children and adults. The viruses are now known to contain a single positive strand of RNA. About 50% of corona virus infections result in clinical illness. About 5% of common colds are caused by strain DC 43 in winter. Chapter 8, Cytomegalovirus: Sections on pathogenesis of CMV in relation to organ transplantation and mononucleosis, as well as sections on the risk and features of con genital infection and disease, have been expanded. There are encouraging preliminary results with a live CMV vaccine, but the questions of viral persistence and oncogenicity require further evaluation.

Adenovirus Methods and Protocols

2008-02-01 Medical
Download Adenovirus Methods and Protocols PDF Online Free

Author :
Release : 2008-02-01
Genre : Medical
Kind : eBook
Book Rating : 777/5 ( reviews)

GET EBOOK


Book Synopsis Adenovirus Methods and Protocols by : William S. M. Wold

Download or read book Adenovirus Methods and Protocols written by William S. M. Wold. This book was released on 2008-02-01. Available in PDF, EPUB and Kindle. Book excerpt: Adenovirus Methods and Protocols, Second Edition, now in two volumes, is an essential resource for adenovirus (Ad) researchers beginning in the field, and an inspirational starting point for researchers looking to branch into new areas of Ad study. In addition to updating and expanding important chapters from the first edition, the authors have added new chapters that address innovative, exciting areas of emphasis in Ad research, including Ad vector construction and use, real-time PCR, use of new animal models, and methods for quantification of Ad virus or virus expression/interactions. The protocols presented are written by trendsetting researchers.

You may also like...