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Supramolecular Chemistry in Biomedical Imaging

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Release : 2022-04-01
Genre : Technology & Engineering
Kind : eBook
Book Rating : 37X/5 ( reviews)

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Book Synopsis Supramolecular Chemistry in Biomedical Imaging by : Stephen Faulkner

Download or read book Supramolecular Chemistry in Biomedical Imaging written by Stephen Faulkner. This book was released on 2022-04-01. Available in PDF, EPUB and Kindle. Book excerpt: There have been many great advances in the field of biomedical imaging in recent years, with supramolecular chemistry playing a key role in the evolution of modern imaging techniques. Non-covalent supramolecular interactions are fundamental to countless biological processes, from host–guest binding to the stabilisation of complex structures. Supramolecular chemistry techniques can be employed to create probes that can be targeted to either exploit or disrupt these interactions, giving the potential for both diagnostic and therapeutic effects. Furthermore, in techniques such as contrast enhanced MRI, controlling the interactions between solvent molecules and the imaging agent is crucial to the development of the technique. With rapid growth in the synthesis and study of molecular imaging agents, the understanding of their associated techniques has sometimes lagged behind. Supramolecular Chemistry in Biomedical Imaging will fill this gap by clarifying the state of current understanding and the nature of the underlying problems inherent to addressing problems in biology. It will cover both the techniques used in imaging and the molecular and supramolecular systems used to exploit them. This publication targets academics coming to the field from mainstream supramolecular chemistry, research graduates and undergraduates interested in supramolecular chemistry, synthesis or imaging agents and imaging techniques for biomedical applications.

Supramolecular Chemistry in Biomedical Imaging

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Author :
Release : 2022-04-01
Genre : Science
Kind : eBook
Book Rating : 977/5 ( reviews)

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Book Synopsis Supramolecular Chemistry in Biomedical Imaging by : Stephen Faulkner

Download or read book Supramolecular Chemistry in Biomedical Imaging written by Stephen Faulkner. This book was released on 2022-04-01. Available in PDF, EPUB and Kindle. Book excerpt: There have been great advances in biomedical imaging techniques in recent years and they are becoming prominent in supramolecular chemistry. This book will clarify the current understanding of these techniques.

Supramolecular Systems in Biomedical Fields

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Release : 2013-09-06
Genre : Science
Kind : eBook
Book Rating : 827/5 ( reviews)

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Book Synopsis Supramolecular Systems in Biomedical Fields by : Hans-Jorg Schneider

Download or read book Supramolecular Systems in Biomedical Fields written by Hans-Jorg Schneider. This book was released on 2013-09-06. Available in PDF, EPUB and Kindle. Book excerpt: Non-covalent interactions, which are the heart of supramolecular chemistry are also the basis of most important functions of living systems. The ability to apply supramolecular chemistry principles to the life sciences, such as designing synthetic host compounds to selectively interact within biological targets, has gained wide appeal due the vast number of potential applications. Supramolecular Systems for Biomedical Fields provides in sixteen chapters a comprehensive overview of these applications. Each chapter covers a specific topic and is written by internationally renowned experts in that area. Sensing of bioactive inorganic ions and organic substrates is the focus of several contributions, as well as interactions with proteins and nucleic acids. Specific chapters are devoted to cyclodextrins, calixarenes and cucurbiturils as most frequently used receptors, including applications such as drug delivery and protection, gene transfer and others. Other chapters address the use of combinatorial libraries, molecular imprinting techniques, enzyme assays, supramolecular gels, bioimaging, drug activation, photodynamic therapy, and antitumour metal complexes. This timely publication will appeal to graduate students and researchers from chemical, pharmaceutical, biological, and medicinal fields interested in the supramolecular chemistry of biological systems and their practical potentials.

New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications

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Release : 2021-05-26
Genre : Medical
Kind : eBook
Book Rating : 563/5 ( reviews)

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Book Synopsis New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications by : Marc J.M. Abadie

Download or read book New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications written by Marc J.M. Abadie. This book was released on 2021-05-26. Available in PDF, EPUB and Kindle. Book excerpt: This contributed volume applies the insights of supramolecular chemistry to biomedical applications such as ions/water transport through nano-scale channels, gene therapy, tissue engineering and drug delivery, to cite some of the major investigations.The challenge is to understand the mechanisms of transport through tissues particularly in the therapeutic treatment of a disease where the active drug must be delivered directly to diseased cells without affecting healthy cells. As a result, smaller quantities of active substances can be used to treat the disease. Another interest concerns new ways to administer gene therapy. If genes are often delivered to their target cells by adapted viruses, the supramolecular non-viral ‘vectors’ using dynamic nano-frameworks and nano-structures are presented. In addition, it is important to reconstruct damaged tissues by mimicking natural processes in cells and polymers, such as tissue engineering and self-healing. Different options are here discussed: e.g. hydrogels based on chitosan, a carbohydrate polymer, are proving especially promising for tissue engineering and drug delivery. For controlled delivery of drugs or other biologically active compounds, hydrogels sensitive to the most important stimuli in the human body, such as temperature, pH, ionic strength, glucose and biomolecules released by the organism in pathological conditions have been developed. Finally, to assist and validate the experimental studies, computer modelling and simulations of large-sized molecular structures and systems using different molecular dynamics and quantum mechanical techniques are developed based on the experimental and chemistry synthesis. This book is of great interest for graduate students, researchers and health professionals interested in acquiring a better understanding of the mechanisms of medical treatments. In addition, it provides numerous tools to develop better therapies for human diseases.

Supramolecular Chemistry

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Release : 2010-08-26
Genre : Science
Kind : eBook
Book Rating : 820/5 ( reviews)

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Book Synopsis Supramolecular Chemistry by : Peter J. Cragg

Download or read book Supramolecular Chemistry written by Peter J. Cragg. This book was released on 2010-08-26. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to return to the biomimicry and medicinal potential that inspired many of the early supramolecular chemists and to set it in the context of current advances in the field. Following an overview of supramolecular chemistry, the first section considers the efforts made to synthesize artificial systems that mimic biological entities. The second section addresses the application of supramolecular principles to molecular diagnostics with a particular emphasis on the ‘receptor-relayreporter’ motif. Many of the examples chosen have clinical importance. The third section takes the clinical diagnostic theme further and demonstrates the therapeutic applications of supramolecular chemistry through photodynamic therapy, drug delivery, and the potential for synthetic peptides to form antibiotic tubes. The short epilogue considers the potential for supramolecular solutions to be found for further challenges in biomimetic and therapeutic chemistry.

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