New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications

2021-05-26 Medical

Author : Marc J.M. Abadie
Release : 2021-05-26
Genre : Medical
Kind : eBook
Book Rating : 563/5 ( reviews)

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Book Synopsis New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications by : Marc J.M. Abadie

Download or read book New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications written by Marc J.M. Abadie. This book was released on 2021-05-26. Available in PDF, EPUB and Kindle. Book excerpt: This contributed volume applies the insights of supramolecular chemistry to biomedical applications such as ions/water transport through nano-scale channels, gene therapy, tissue engineering and drug delivery, to cite some of the major investigations.The challenge is to understand the mechanisms of transport through tissues particularly in the therapeutic treatment of a disease where the active drug must be delivered directly to diseased cells without affecting healthy cells. As a result, smaller quantities of active substances can be used to treat the disease. Another interest concerns new ways to administer gene therapy. If genes are often delivered to their target cells by adapted viruses, the supramolecular non-viral ‘vectors’ using dynamic nano-frameworks and nano-structures are presented. In addition, it is important to reconstruct damaged tissues by mimicking natural processes in cells and polymers, such as tissue engineering and self-healing. Different options are here discussed: e.g. hydrogels based on chitosan, a carbohydrate polymer, are proving especially promising for tissue engineering and drug delivery. For controlled delivery of drugs or other biologically active compounds, hydrogels sensitive to the most important stimuli in the human body, such as temperature, pH, ionic strength, glucose and biomolecules released by the organism in pathological conditions have been developed. Finally, to assist and validate the experimental studies, computer modelling and simulations of large-sized molecular structures and systems using different molecular dynamics and quantum mechanical techniques are developed based on the experimental and chemistry synthesis. This book is of great interest for graduate students, researchers and health professionals interested in acquiring a better understanding of the mechanisms of medical treatments. In addition, it provides numerous tools to develop better therapies for human diseases.

Supramolecular Design for Biological Applications

2002-03-11 Medical

Author : Nobuhiko Yui
Release : 2002-03-11
Genre : Medical
Kind : eBook
Book Rating : 656/5 ( reviews)

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Book Synopsis Supramolecular Design for Biological Applications by : Nobuhiko Yui

Download or read book Supramolecular Design for Biological Applications written by Nobuhiko Yui. This book was released on 2002-03-11. Available in PDF, EPUB and Kindle. Book excerpt: Supramolecular chemistry is the outburst topic of the next generation of science. While the majority of biomedical research efforts to date have centered on utilizing well-known polymeric materials, the recent progress in supramolecular chemistry has introduced a fascinating new field of macromolecular architecture. Supramolecular Design for Biological Applications focuses on modulating, altering, and mimicking biological functions with a new family of molecular assemblies. The authors provide innovative ideas and concepts for developing novel biomaterials that could be applied in diagnosis, drug carrier operations, and environmental protection. This reference is comprehensive, presenting principles, applications, recent advances, and future directions. Each chapter includes clear and informative illustrations of molecular architectures. The writing is scientific but allows for easy comprehension of the differences in molecular interactions, dimensions, and supramolecular architecture. Supramolecular Design for Biological Applications will advance the understanding of supramolecular-structured biomaterials and associated issues regarding biological functions. By explaining recent trends and molecular interactions, this book will enable you to initiate new research for nano-scale science and technology in the 21st century.

Supramolecular Chemistry

2013-05-21 Science

Author : Jonathan W. Steed
Release : 2013-05-21
Genre : Science
Kind : eBook
Book Rating : 509/5 ( reviews)

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Book Synopsis Supramolecular Chemistry by : Jonathan W. Steed

Download or read book Supramolecular Chemistry written by Jonathan W. Steed. This book was released on 2013-05-21. Available in PDF, EPUB and Kindle. Book excerpt: Supramolecular chemistry is ‘chemistry beyond the molecule’ - the chemistry of molecular assemblies and intermolecular bonds. It is one of today’s fastest growing disciplines, crossing a range of subjects from biological chemistry to materials science; and from synthesis to spectroscopy. Supramolecular Chemistry is an up-to-date, integrated textbook that tells the newcomer to the field everything they need to know to get started. Assuming little in the way of prior knowledge, the book covers the concepts behind the subject, its breadth, applications and the latest contemporary thinking in the area. It also includes coverage of the more important experimental and instrumental techniques needed by supramolecular chemists. The book has been thoroughly updated for this second edition. In addition to the strengths of the very popular first edition, this comprehensive new version expands coverage into a broad range of emerging areas. Clear explanations of both fundamental and nascent concepts are supplemented by up-to-date coverage of exciting emerging trends in the literature. Numerous examples and problems are included throughout the book. A system of “key references” allows rapid access to the secondary literature, and of course comprehensive primary literature citations are provided. A selection of the topics covered is listed below. Cation, anion, ion-pair and molecular host-guest chemistry Crystal engineering Topological entanglement Clathrates Self-assembly Molecular devices Dendrimers Supramolecular polymers Microfabrication Nanoparticles Chemical emergence Metal-organic frameworks Gels Ionic liquids Supramolecular catalysis Molecular electronics Polymorphism Gas sorption Anion-pinteractions Nanochemistry Supramolecular Chemistry is a must for both students new to the field and for experienced researchers wanting to explore the origins and wider context of their work. Review: "At just under 1000 pages, the second edition of Steed and Atwood's Supramolecular Chemistry is the most comprehensive overview of the area available in textbook form...highly recommended." —Chemistry World, August 2009

Supramolecular Chemistry

2010-08-26 Science

Author : Peter J. Cragg
Release : 2010-08-26
Genre : Science
Kind : eBook
Book Rating : 820/5 ( reviews)

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Book Synopsis Supramolecular Chemistry by : Peter J. Cragg

Download or read book Supramolecular Chemistry written by Peter J. Cragg. This book was released on 2010-08-26. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to return to the biomimicry and medicinal potential that inspired many of the early supramolecular chemists and to set it in the context of current advances in the field. Following an overview of supramolecular chemistry, the first section considers the efforts made to synthesize artificial systems that mimic biological entities. The second section addresses the application of supramolecular principles to molecular diagnostics with a particular emphasis on the ‘receptor-relayreporter’ motif. Many of the examples chosen have clinical importance. The third section takes the clinical diagnostic theme further and demonstrates the therapeutic applications of supramolecular chemistry through photodynamic therapy, drug delivery, and the potential for synthetic peptides to form antibiotic tubes. The short epilogue considers the potential for supramolecular solutions to be found for further challenges in biomimetic and therapeutic chemistry.

Supramolecular Materials and Technologies

2008-04-30 Technology & Engineering

Author : David N. Reinhoudt
Release : 2008-04-30
Genre : Technology & Engineering
Kind : eBook
Book Rating : 486/5 ( reviews)

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Book Synopsis Supramolecular Materials and Technologies by : David N. Reinhoudt

Download or read book Supramolecular Materials and Technologies written by David N. Reinhoudt. This book was released on 2008-04-30. Available in PDF, EPUB and Kindle. Book excerpt: Perspectives in Supramolecular Chemistry relates recent developments and new exciting approaches in supramolecular chemistry. The series covers all areas from theoretical and modelling aspects through organic and inorganic chemistry and biochemistry to materials, solid-state and polymer sciences reflecting the many and varied applications of supramolecular structures in modern chemistry. From the early days of supramolecular chemistry the field has been associated with possible applications. This is not surprising as the design of new molecules, and later of assemblies of molecules, is often function-driven. Now, after three decades of supramolecular chemistry, David Reinhoudt has brought together a collection of reviews to reflect on the applications that have actually been achieved. The first applications in molecular recognition are now established technologies in analytical chemistry, separation science and medicine. More recently, developments have taken place in material design and these concepts are also discussed here. Contents * Self-Assembling Systems on Scales from Nanometers to Millimeters: Design and Discovery * Dendritic Architectures * Supramolecular Structures with Macromolecules * Chemosensors: Synthetic Receptors in Analytical Sensing Applications * Selective Ion Recognition with Durable Sensors * Ion Separations in Membrane and Solid Phase Extraction Systems * Porphyrin- and Expanded Pophyrin-Based Diagnostic and Therapeutic Agents Supramolecular Materials and Technologies illustrates the achievements and advances that supramolecular chemistry has made in many fields from organic chemistry to materials science and from analytical chemistry to molecular biology.

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