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Signaling Pathways in Cancer Pathogenesis and Therapy

2011-11-12 Medical
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Release : 2011-11-12
Genre : Medical
Kind : eBook
Book Rating : 161/5 ( reviews)

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Book Synopsis Signaling Pathways in Cancer Pathogenesis and Therapy by : David A. Frank

Download or read book Signaling Pathways in Cancer Pathogenesis and Therapy written by David A. Frank. This book was released on 2011-11-12. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, increasing evidence has suggested that abnormal activation of signaling pathways is a critical event in cancer pathogenesis. In particular, activation of these pathways can lead to inappropriate cellular survival, proliferation, pluripotency, invasion, metastasis, and angiogenesis. Thus, understanding the mechanisms by which signaling pathways become subverted in a cancer cell can provide insight into critical events in cancer pathogenesis. Furthermore, as our ability to target specific molecular interactions advances, we now have the ability to design small molecules, protein therapeutics, and other forms of targeted therapies. By focusing on the specific molecular abnormalities in a cancer cell, these agents hold the potential to be much more effective and much less toxic than current cytotoxic therapies.

Signaling Pathways in Cancer Pathogenesis and Therapy

2011-11-13
Download Signaling Pathways in Cancer Pathogenesis and Therapy PDF Online Free

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Release : 2011-11-13
Genre :
Kind : eBook
Book Rating : 175/5 ( reviews)

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Book Synopsis Signaling Pathways in Cancer Pathogenesis and Therapy by :

Download or read book Signaling Pathways in Cancer Pathogenesis and Therapy written by . This book was released on 2011-11-13. Available in PDF, EPUB and Kindle. Book excerpt:

Nitric Oxide and Cancer: Pathogenesis and Therapy

2015-05-12 Medical
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Release : 2015-05-12
Genre : Medical
Kind : eBook
Book Rating : 119/5 ( reviews)

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Book Synopsis Nitric Oxide and Cancer: Pathogenesis and Therapy by : Benjamin Bonavida

Download or read book Nitric Oxide and Cancer: Pathogenesis and Therapy written by Benjamin Bonavida. This book was released on 2015-05-12. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Nitric Oxide and Cancer is a volume that serves to give the latest research on nitric oxide (NO) and cancer. More specifically, the volume reviews significant advances in the application of NO-mediated drugs. The volume explores nitric oxide and its relationship to cancer spanning from its roles in the pathogenesis, prognosis, gene and protein modifications, regulation of resistance to cytotoxics, and therapeutic applications. With chapters written by leading experts, the volume addresses the burgeoning interest in a rapidly advancing field and provides a valuable resource to scientists who have initiated research as well as clinical investigations in their laboratories on the various roles of NO and cancer.

Caveolins in Cancer Pathogenesis, Prevention and Therapy

2011-11-03 Medical
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Release : 2011-11-03
Genre : Medical
Kind : eBook
Book Rating : 010/5 ( reviews)

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Book Synopsis Caveolins in Cancer Pathogenesis, Prevention and Therapy by : Isabelle Mercier

Download or read book Caveolins in Cancer Pathogenesis, Prevention and Therapy written by Isabelle Mercier. This book was released on 2011-11-03. Available in PDF, EPUB and Kindle. Book excerpt: Caveolins are important structural proteins of Caveolae, small invaginations of the membrane. They have been shown to play an important role in the pathogenesis of multiple cancers. In this volume, we will mainly focus on the importance of Caveolin-1 in breast, prostate, lung, skin, colon, pancreatic and brain cancers with also a mention of the novel role of Caveolin-3 in breast cancer.

Signal Transduction in Cancer

2002-12-31 Medical
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Release : 2002-12-31
Genre : Medical
Kind : eBook
Book Rating : 402/5 ( reviews)

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Book Synopsis Signal Transduction in Cancer by : David A. Frank

Download or read book Signal Transduction in Cancer written by David A. Frank. This book was released on 2002-12-31. Available in PDF, EPUB and Kindle. Book excerpt: One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."

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