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Signal Transduction in Cancer

2002-12-31 Medical
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Release : 2002-12-31
Genre : Medical
Kind : eBook
Book Rating : 402/5 ( reviews)

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Book Synopsis Signal Transduction in Cancer by : David A. Frank

Download or read book Signal Transduction in Cancer written by David A. Frank. This book was released on 2002-12-31. Available in PDF, EPUB and Kindle. Book excerpt: One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."

Signal Transduction in Cancer

2006-04-18 Medical
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Release : 2006-04-18
Genre : Medical
Kind : eBook
Book Rating : 588/5 ( reviews)

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Book Synopsis Signal Transduction in Cancer by : David A. Frank

Download or read book Signal Transduction in Cancer written by David A. Frank. This book was released on 2006-04-18. Available in PDF, EPUB and Kindle. Book excerpt: One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."

Signal Transduction in Cancer Metastasis

2010-10-04 Medical
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Release : 2010-10-04
Genre : Medical
Kind : eBook
Book Rating : 225/5 ( reviews)

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Book Synopsis Signal Transduction in Cancer Metastasis by : Wen-Sheng Wu

Download or read book Signal Transduction in Cancer Metastasis written by Wen-Sheng Wu. This book was released on 2010-10-04. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the signal mechanisms responsible for triggering a series of phenotypical changes of primary tumor which may lead to final colonization of the tumor in a second home. It highlights the initial stage of tumor metastasis.

Cancer Cell Signaling

2014-06-20 Medical
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Release : 2014-06-20
Genre : Medical
Kind : eBook
Book Rating : 453/5 ( reviews)

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Book Synopsis Cancer Cell Signaling by : Kasirajan Ayyanathan

Download or read book Cancer Cell Signaling written by Kasirajan Ayyanathan. This book was released on 2014-06-20. Available in PDF, EPUB and Kindle. Book excerpt: This title includes a number of Open Access chapters.Cell signaling is a field that studies how cells communicate to control basic activities and respond to their environment. When looking specifically at cancer cells, researchers can gain a better understanding of cancer on a cellular level, an understanding that may have implications for developi

Advances in Cancer Signal Transduction and Therapy

2020-10-05 Medical
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Release : 2020-10-05
Genre : Medical
Kind : eBook
Book Rating : 09X/5 ( reviews)

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Book Synopsis Advances in Cancer Signal Transduction and Therapy by : Manoj K. Pandey

Download or read book Advances in Cancer Signal Transduction and Therapy written by Manoj K. Pandey. This book was released on 2020-10-05. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is driven by numerous genetic and epigenetic changes occurring at the cellular level. These changes drive normal cells to proliferate and escape processes that usually regulate their survival and migration. Many of these alterations are often associated with signaling pathways which regulate cell growth and division, cell death, survival, invasion and metastasis, and angiogenesis. Almost all cancer cells show high expression of signaling components including growth factor receptor tyrosine kinases (RTKs), small GTPases, serine/threonine kinases, cytoplasmic tyrosine kinases, lipid kinases, estrogen receptor, activation of transcription factors Myc and NF-κB, etc. Updated knowledge about these signaling components is highly desirable for researchers involved in developing therapies against cancer. Signal Transduction Research for Cancer Therapy covers advancements in research on the signaling pathways in the human body, especially in some types of cancers, such as breast cancer, pancreatic cancer and colon cancer. Key features of this volume include 8 focused topical reviews on signaling pathways in a specific cancer type, coverage of multiple cancer types (breast cancer, colon cancer, hepatocellular cancer, multiple myeloma, acute myeloid leukemia, and pancreatic cancer), and coverage of a wide array of signaling pathways (both receptor mediated and non receptor mediated pathways). This volume is essential reading for researchers in pharmaceutical R&D and postgraduate research programs in pharmacology and allied disciplines. Clinicians involved in oncology will also benefit from the information provided in the chapters. [Series Intro] This series provides scientists and clinicians with updated clinical information about signal transduction that will be valuable in their pursuit to investigate, develop, and apply novel agents to prevent or treat life-threatening diseases such as cancer. Contributions to the series will focus on methods that also enhance the quality of life for patients.

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