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Signal Transduction: Pathways, Mechanisms and Diseases

2009-12-02 Science
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Release : 2009-12-02
Genre : Science
Kind : eBook
Book Rating : 123/5 ( reviews)

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Book Synopsis Signal Transduction: Pathways, Mechanisms and Diseases by : Ari Sitaramayya

Download or read book Signal Transduction: Pathways, Mechanisms and Diseases written by Ari Sitaramayya. This book was released on 2009-12-02. Available in PDF, EPUB and Kindle. Book excerpt: Providing an overview of recent developments in the field of signal transduction, this volume emphasizes direct clinical significance. As such, topics like nuclear receptors, apoptosis, growth factors, cell cycles and cancer are examined.

Signal Transduction and Human Disease

2003-07-18 Science
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Release : 2003-07-18
Genre : Science
Kind : eBook
Book Rating : 370/5 ( reviews)

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Book Synopsis Signal Transduction and Human Disease by : Toren Finkel

Download or read book Signal Transduction and Human Disease written by Toren Finkel. This book was released on 2003-07-18. Available in PDF, EPUB and Kindle. Book excerpt: This book uniquely relates the broad impact of signal transduction research on the understanding and treatment of human disease. There have been significant advances in the area of signaling in disease processes, yet no resource presently connects these advances with understanding of disease processes and applications for novel therapeutics. Given the emphasis on translational research and biological relevance in biotechnology, and, conversely, the importance of molecular approaches for clinical research, it is evident that a single resource bridging signaling research and human disease will be invaluable.

Trends in Signal Transduction Research

2007 Medical
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Release : 2007
Genre : Medical
Kind : eBook
Book Rating : 755/5 ( reviews)

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Book Synopsis Trends in Signal Transduction Research by : Jennifer N. Meyers

Download or read book Trends in Signal Transduction Research written by Jennifer N. Meyers. This book was released on 2007. Available in PDF, EPUB and Kindle. Book excerpt: Signal transduction is any process by which a cell converts one kind of signal or stimulus into another. Processes referred to as signal transduction often involve a sequence of biochemical reactions inside the cell, which are carried out by enzymes and linked through second messengers. In many transduction processes, an increasing number of enzymes and other molecules become engaged in the events that proceed from the initial stimulus. Responses of cells to environmental signals, toxins and stressors have profound implications for diverse aspects of human health and disease including development, cystic fibrosis, diabetes, asthma, heart, autoimmune diseases and cancer. The delineation of the signal transduction pathways affected in these and other complex human diseases are likely to present new avenues for therapeutic intervention and understanding of human disease mechanisms.

Regulation of Signal Transduction in Human Cell Research

2018-02-15 Medical
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Release : 2018-02-15
Genre : Medical
Kind : eBook
Book Rating : 965/5 ( reviews)

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Book Synopsis Regulation of Signal Transduction in Human Cell Research by : Nariyoshi Shinomiya

Download or read book Regulation of Signal Transduction in Human Cell Research written by Nariyoshi Shinomiya. This book was released on 2018-02-15. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the relationship between the regulation of signal transduction and disease mechanisms, and discusses how the dysregulation of intracellular signals cause diseases, cell death, carcinogenesis, and other disorders. Growth, survival, transformation, and metabolic activities at the cellular level are regulated by various intracellular signal transduction pathways. Sources that stimulate intracellular signals include intracellular stresses and signal regulators/modulators, as well as extracellular growth factors. Recent studies on signal transduction analysis using animal and human cell lines have revealed how the intracellular signals are regulated and why their dysregulation leads to pathological states such as tumorigenesis, metabolic diseases, cell death, and so on. This book highlights several important key molecules and intracellular signaling pathways such as microRNA, the TGF-beta signaling pathway, the Wnt signaling pathway and MET signaling pathway as topical and highly relevant issues in human cell research related to signal transduction. In addition to assessing the pathogenic role of these signaling pathways, it focuses on the molecular design of small molecule regulators/inhibitors of said pathways, one of the most important approaches in this area. This book offers a valuable guide, helping not only research scientists but also clinicians to understand how the dysregulation of intracellular signals leads to diseases.

Signal Transduction in Cancer

2002-12-31 Medical
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Release : 2002-12-31
Genre : Medical
Kind : eBook
Book Rating : 402/5 ( reviews)

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Book Synopsis Signal Transduction in Cancer by : David A. Frank

Download or read book Signal Transduction in Cancer written by David A. Frank. This book was released on 2002-12-31. Available in PDF, EPUB and Kindle. Book excerpt: One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."

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