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Quantifying and Controlling the Nano-Architecture of Neuronal Synapses

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Release : 2022-09-27
Genre : Science
Kind : eBook
Book Rating : 846/5 ( reviews)

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Book Synopsis Quantifying and Controlling the Nano-Architecture of Neuronal Synapses by : Xiaobing Chen

Download or read book Quantifying and Controlling the Nano-Architecture of Neuronal Synapses written by Xiaobing Chen. This book was released on 2022-09-27. Available in PDF, EPUB and Kindle. Book excerpt:

Recent Advances in Measuring and Controlling Synaptic Communication

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Release : 2023-11-10
Genre : Science
Kind : eBook
Book Rating : 379/5 ( reviews)

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Book Synopsis Recent Advances in Measuring and Controlling Synaptic Communication by : Jacopo Lamanna

Download or read book Recent Advances in Measuring and Controlling Synaptic Communication written by Jacopo Lamanna. This book was released on 2023-11-10. Available in PDF, EPUB and Kindle. Book excerpt: Synapses represent a unique neuronal compartment specialized in communication. The morpho-functional investigation of the synapse has always been hindered by its tiny size and high density of molecular elements, but specific technological and methodological advances helped us to reduce these limitations. As the matter of fact, in recent years, we have witnessed the continuous development of new methods allowing measuring and controlling synaptic activation both in vitro and in vivo. These include new genetically encoded sensors of synaptic exo-endocytosis, but also engineered synaptic proteins able to inhibit the release of neurotransmitters. Furthermore, new promising tools allow changing the functional properties of synapses in a plasticity-like manner. All these methodological advances are likely to generate unprecedented knowledge about the dynamics of synaptic transmission and plasticity at several levels of the nervous system. Nevertheless, in most cases, the implementation of these new methods remains technically demanding, likely due to the high complexity of their operating principle. Hence, it would be worth refining and potentiating these tools in order to extend the range of experimental settings for their application.

Spike-based learning application for neuromorphic engineering

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Release : 2024-08-22
Genre : Science
Kind : eBook
Book Rating : 184/5 ( reviews)

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Book Synopsis Spike-based learning application for neuromorphic engineering by : Anup Das

Download or read book Spike-based learning application for neuromorphic engineering written by Anup Das . This book was released on 2024-08-22. Available in PDF, EPUB and Kindle. Book excerpt: Spiking Neural Networks (SNN) closely imitate biological networks. Information processing occurs in both spatial and temporal manner, making SNN extremely interesting for the pertinent mimicking of the biological brain. Biological brains code and transmit the sensory information in the form of spikes that capture the spatial and temporal information of the environment with amazing precision. This information is processed in an asynchronous way by the neural layer performing recognition of complex spatio-temporal patterns with sub-milliseconds delay and at with a power budget in the order of 20W. The efficient spike coding mechanism and the asynchronous and sparse processing and communication of spikes seems to be key in the energy efficiency and high-speed computation capabilities of biological brains. SNN low-power and event-based computation make them more attractive when compared to other artificial neural networks (ANN).

Molecular Nanomachines of the Presynaptic Terminal

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Release : 2016-10-18
Genre : Neurosciences. Biological psychiatry. Neuropsychiatry
Kind : eBook
Book Rating : 983/5 ( reviews)

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Book Synopsis Molecular Nanomachines of the Presynaptic Terminal by : Silvio O. Rizzoli

Download or read book Molecular Nanomachines of the Presynaptic Terminal written by Silvio O. Rizzoli. This book was released on 2016-10-18. Available in PDF, EPUB and Kindle. Book excerpt: Synaptic transmission is the basis of neuronal communication and is thus the most important element in brain functions, ranging from sensory input to information processing. Changes in synaptic transmission can result in the formation or dissolution of memories, and can equally lead to neurological and psychiatric disorders. The proteins composing the synapse, and their respective functions, are getting increasingly known. One aspect that has become evident in the last years is that most synaptic functions are performed not by single proteins, but by highly organized multi-protein machineries, which interact dynamically to provide responses optimally suited to the needs of the neuronal network. To decipher synaptic and neuronal function, it is essential to understand the organisational, morphological and functional aspects of the molecular nanomachines that operate at the synapse. We discuss these aspects in 11 different chapters, focusing on the structure and function of the active zone, on the functional anatomy of the synaptic vesicle, and on some of the best known soluble protein complexes from the synapse, including those involved in endocytosis and vesicle recycling.

The Synapse

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Release : 2012
Genre : Neural transmission
Kind : eBook
Book Rating : 026/5 ( reviews)

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Book Synopsis The Synapse by : Morgan Sheng

Download or read book The Synapse written by Morgan Sheng. This book was released on 2012. Available in PDF, EPUB and Kindle. Book excerpt: "A subject collection from Cold Spring Harbor perspectives in biology"--T.p. verso.

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