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Pharmacology of Cytokines

2000 Medical
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Release : 2000
Genre : Medical
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Pharmacology of Cytokines by : Alberto Mantovani

Download or read book Pharmacology of Cytokines written by Alberto Mantovani. This book was released on 2000. Available in PDF, EPUB and Kindle. Book excerpt: Cytokines are the "words" of immunity, serving as mediators within and outside the immune system. There is tremendous interest in their expliotation as therapeutic tools in diverse human diseases and considerable effort has been made to understand and utilize their pharmacology. This book examines this pharmacology, from developments and characterization of simple chemicals and their mechanism of action to the use of biotechnology-based approaches. The book puts cytokines and their pharmacology in context and examines their involvement in individual organ-disease systems.

Immunopharmacology

2008-12-19 Medical
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Release : 2008-12-19
Genre : Medical
Kind : eBook
Book Rating : 760/5 ( reviews)

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Book Synopsis Immunopharmacology by : Manzoor M. Khan

Download or read book Immunopharmacology written by Manzoor M. Khan. This book was released on 2008-12-19. Available in PDF, EPUB and Kindle. Book excerpt: During the past decades, with the introduction of the recombinant DNA, hybridoma and transgenic technologies there has been an exponential evolution in understanding the pathogenesis, diagnosis and treatment of a large number of human diseases. The technologies are evident with the development of cytokines and monoclonal antibodies as therapeutic agents and the techniques used in gene therapy. Immunopharmacology is that area of biomedical sciences where immunology, pharmacology and pathology overlap. It concerns the pharmacological approach to the immune response in physiological as well as pathological events. This goals and objectives of this textbook are to emphasize the developments in immunology and pharmacology as they relate to the modulation of immune response. The information includes the pharmacology of cytokines, monoclonal antibodies, mechanism of action of immune-suppressive agents and their relevance in tissue transplantation, therapeutic strategies for the treatment of AIDS and the techniques employed in gene therapy. The book is intended for health care professional students and graduate students in pharmacology and immunology.

New Cytokines as Potential Drugs

2012-11-19 Medical
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Release : 2012-11-19
Genre : Medical
Kind : eBook
Book Rating : 567/5 ( reviews)

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Book Synopsis New Cytokines as Potential Drugs by : Satwant K. Narula

Download or read book New Cytokines as Potential Drugs written by Satwant K. Narula. This book was released on 2012-11-19. Available in PDF, EPUB and Kindle. Book excerpt: Over the past ten years, a number of cytokines and growth factors have proven to be as effective therapeutics. While these products have certainly established recombinant biologics as a major pharmaceutical growth sector, the continued interest in this class of drugs arises from the fact that today we have a far better understanding of the human immune response, both at a cellular and molecular level. This has resulted in a more methodical characterisation of these factors which has given clinical researchers an opportunity to plan Phase 1 clinical trials that can provide substantial information on the activity of the cytokine in humans. Currently, a great deal of effort is also being channelled into identifying cytokines from the various DNA databases. Our major objective for this book is to profile cytokines that have been recently identified. The therapeutic potential of these cytokines based on their known properties will be discussed by the authors. The main aim of this book is to provide...

Cytokines

1998-04-15 Medical
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Release : 1998-04-15
Genre : Medical
Kind : eBook
Book Rating : 214/5 ( reviews)

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Book Synopsis Cytokines by : Anthony R. Mire-Sluis

Download or read book Cytokines written by Anthony R. Mire-Sluis. This book was released on 1998-04-15. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive coverage of the cytokines from a pharmacological approach. The chapters are presented in a consistent format allowing easy cross-reference, with sample diagrams and a summary table of essential facts for each chapter at the end of the book.Cytokines is unique in stressing cytokine biology and the application of research data to provide disease therapy. With 33 detailed and up-to-date chapters about individual cytokines, this comprehensive reference will provide both clinicians and researchers in immunology and pharmacology with invaluable information. - Genetic information and sequences - Protein structure - Cell sources and production - Biological activity - Cytokine receptor structure and signal transduction - Discussion of the role of cytokines in disease and the potential for therapy - Summary table of essential facts - Comprehensive bibliography

Novel Cytokine Inhibitors

2012-12-06 Medical
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Release : 2012-12-06
Genre : Medical
Kind : eBook
Book Rating : 508/5 ( reviews)

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Book Synopsis Novel Cytokine Inhibitors by : Gerry A. Higgs

Download or read book Novel Cytokine Inhibitors written by Gerry A. Higgs. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: Cytokines have become established as key mediators of the signs and symptoms of inflammatory diseases such as arthritis, dermatitis, asthma and multiple sclerosis. Furthermore, they are involved in the cascade of events leading to cardiovascular shock and are major regulators of the function of immune cells. This book reviews recent advances in the development of new anti-inflammatory drugs. It addresses different therapeutic intervention possibilities for new drugs, such as the cellular source of cytokines, specific receptors which induce cytokine synthesis, intracellular regulators of cytokine gene induction and expression, secretion and activation of cytokines, cytokine receptors and signalling pathways from these receptors. Accordingly, experts were drawn from different backgrounds including academic research institutes, the pharmaceutical industry and clinical pharmacology. In each area, the opportunities for drug development are highlighted and, where possible, clinical data is reviewed.

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