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Author : Konrad Beyreuther
Release : 2012-12-06
Genre : Medical
Kind : eBook
Book Rating : 240/5 ( reviews)
Book Synopsis Molecular Mechanisms of Aging by : Konrad Beyreuther
Download or read book Molecular Mechanisms of Aging written by Konrad Beyreuther. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Konrad Beyreuther
Release : 1990-07-23
Genre :
Kind : eBook
Book Rating : 252/5 ( reviews)
Book Synopsis Molecular Mechanisms of Aging by : Konrad Beyreuther
Download or read book Molecular Mechanisms of Aging written by Konrad Beyreuther. This book was released on 1990-07-23. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Konrad Beyreuther
Release : 1990
Genre : Family & Relationships
Kind : eBook
Book Rating : /5 ( reviews)
Book Synopsis Molecular Mechanisms of Aging by : Konrad Beyreuther
Download or read book Molecular Mechanisms of Aging written by Konrad Beyreuther. This book was released on 1990. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Christian Behl
Release : 2013-12-18
Genre : Science
Kind : eBook
Book Rating : 799/5 ( reviews)
Book Synopsis Cell Aging: Molecular Mechanisms and Implications for Disease by : Christian Behl
Download or read book Cell Aging: Molecular Mechanisms and Implications for Disease written by Christian Behl. This book was released on 2013-12-18. Available in PDF, EPUB and Kindle. Book excerpt: Aging represents a physiological and per se non-pathological and multifactorial process involving a set of key genes and mechanisms being triggered by different endogenous and exogenous factors. Since aging is a major risk factor in connection with a variety of human disorders, it is increasingly becoming a central topic in biochemical and medical research. The plethora of theories on aging – some of which have been discussed for decades – are neither isolated nor contradictory but instead can be connected in a network of pathways and processes at the cellular and molecular levels. This book summarizes the most prominent and important approaches, focusing on telomeres, DNA damage and oxidative stress as well as on the possible role of nutrition, the interplay between genes and environment (epigenetics) and intracellular protein homeostasis and introduces some genes that have actually extended life spans in animal models. Linking these different determinants of aging with disease, this volume aims to reveal their multiple interdependencies. We see that there is no single “perfect” theory of aging and that instead it is possible to define what the authors call the molecular aging matrix of the cell. A better knowledge of its key mechanisms and the mutual connections between its components will lead to a better understanding of age-associated disorders such as Alzheimer’s disease.
Author : Vladimir Titorenko
Release : 2019-08-19
Genre : Science
Kind : eBook
Book Rating : 555/5 ( reviews)
Book Synopsis Aging and Age-Related Disorders From Molecular Mechanisms to Therapies by : Vladimir Titorenko
Download or read book Aging and Age-Related Disorders From Molecular Mechanisms to Therapies written by Vladimir Titorenko. This book was released on 2019-08-19. Available in PDF, EPUB and Kindle. Book excerpt: Aging of unicellular and multicellular eukaryotic organisms is a convoluted biological phenomenon, which is manifested as an age-related functional decline caused by progressive dysregulation of certain cellular and organismal processes. Many chronic diseases are associated with human aging. These aging-associated diseases include cardiovascular diseases, chronic obstructive pulmonary disease, chronic kidney disease, diabetes, osteoarthritis, osteoporosis, sarcopenia, stroke, neurodegenerative diseases (including Parkinson’s, Alzheimer’s, and Huntington’s diseases), and many forms of cancer. Studies in yeast, roundworms, fruit flies, fishes, mice, primates, and humans have provided evidence that the major aspects and basic mechanisms of aging and aging-associated pathology are conserved across phyla. The focus of this International Journal of Molecular Sciences Special Issue is on molecular and cellular mechanisms, diagnostics, and therapies and diseases of aging. Fifteen original research and review articles in this Special Issue provide important insights into how various genetic, dietary, and pharmacological interventions can affect certain longevity-defining cellular and organismal processes to delay aging and postpone the onset of age-related pathologies in evolutionarily diverse organisms. These articles outline the most important unanswered questions and directions for future research in the vibrant and rapidly evolving fields of mechanisms of biological aging, aging-associated diseases, and aging-delaying therapies.
