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MicroRNAs in Medicine

2013-10-30 Science
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Release : 2013-10-30
Genre : Science
Kind : eBook
Book Rating : 343/5 ( reviews)

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Book Synopsis MicroRNAs in Medicine by : Charles H. Lawrie

Download or read book MicroRNAs in Medicine written by Charles H. Lawrie. This book was released on 2013-10-30. Available in PDF, EPUB and Kindle. Book excerpt: MicroRNAs in Medicine provides an access point into the current literature on microRNA for both scientists and clinicians, with an up-to-date look at what is happening in the emerging field of microRNAs and their relevance to medicine. Each chapter is a comprehensive review, with descriptions of the latest microRNA research written by international leaders in their field. Opening with an introduction to what microRNAs are and how they function, the book goes on to explore the role of microRNAs in normal physiological functions, infectious diseases, non-infectious diseases, cancer, circulating microRNAs as non-invasive biomarkers, and finally their potential as novel therapeutics. Including background information on the field as well as reviews of the latest research breakthroughs, MicroRNAs in Medicine is a one-stop source of information to satisfy the specialists and non-specialists alike, appealing to students, researchers, and clinicians interested in understanding the potential of microRNAs in medicine and research.

MicroRNAs in Diseases and Disorders

2019-05-07 Science
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Release : 2019-05-07
Genre : Science
Kind : eBook
Book Rating : 811/5 ( reviews)

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Book Synopsis MicroRNAs in Diseases and Disorders by : Philip V Peplow

Download or read book MicroRNAs in Diseases and Disorders written by Philip V Peplow. This book was released on 2019-05-07. Available in PDF, EPUB and Kindle. Book excerpt: From pathology to treatment, MicroRNAs in Diseases and Disorders highlights the role of microRNAs (miRNAs) in the development and progression of a variety of diseases, including cancer, neurological disease, endocrine disease and autoimmune disease, and underscores the utilization of miRNA targets in the treatment of these conditions. Providing a comprehensive account, this book also includes the identification of miRNAs as diagnostic and prognostic biomarkers for disease, as well as evaluates translational value from clinical trials using synthesized and functionalized miRNA mimics and inhibitors. With a global contribution list and chapters from leading experts across the field, MicroRNAs in Diseases and Disorders is an invaluable reference to miRNA researchers and health professionals in a variety of disease areas in government, academia and industry. The book will also appeal to pharmaceutical and medicinal chemists with an interest in miRNA targeting therapeutics, as well as to advanced students in chemical biology and drug discovery.

Circulating MicroRNAs

2013-05-30 Medical
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Release : 2013-05-30
Genre : Medical
Kind : eBook
Book Rating : 524/5 ( reviews)

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Book Synopsis Circulating MicroRNAs by : Takahiro Ochiya

Download or read book Circulating MicroRNAs written by Takahiro Ochiya. This book was released on 2013-05-30. Available in PDF, EPUB and Kindle. Book excerpt: microRNAs (miRNAs) are small non-coding RNAs that regulate various biological phenomena, such as development and homeostasis. The dysregulation of miRNA leads to disease progression, particularly of cancer. In Circulating MicroRNAs: Methods and Protocols, expert researchers in the field detail recent advances in the isolation, purification and analysis of circulating miRNAs from a variety of sources for research. The book is divided into three main topics. The first section involves the study of secretory miRNAs in cell-cell communication, and the second, the study of circulating miRNAs in body fluids. The last describes the novel techniques used to study circulating miRNAs. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Circulating MicroRNAs: Methods and Protocols seeks to aid scientists in dealing with the recent advances of RNAi technology from the bench to the bedside.

Circulating microRNAs in Disease Diagnostics and their Potential Biological Relevance

2015-11-25 Medical
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Release : 2015-11-25
Genre : Medical
Kind : eBook
Book Rating : 557/5 ( reviews)

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Book Synopsis Circulating microRNAs in Disease Diagnostics and their Potential Biological Relevance by : Peter Igaz

Download or read book Circulating microRNAs in Disease Diagnostics and their Potential Biological Relevance written by Peter Igaz. This book was released on 2015-11-25. Available in PDF, EPUB and Kindle. Book excerpt: MicroRNAs as the endogenous mediators of RNA interference have experienced an unprecedented career in recent years, highlighting their pathogenic, diagnostic and potential therapeutic relevance. Beside tissue microRNAs, they are also found in body fluids, most notably in blood. Significant differences of circulating microRNA levels have been found in various diseases, making them candidates for minimally invasive markers of disease, for example tumor malignancy. The book focuses on the potential diagnostic applicability of circulating microRNAs in various diseases and their potential biological significance.

microRNA: Medical Evidence

2015-12-11 Science
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Release : 2015-12-11
Genre : Science
Kind : eBook
Book Rating : 711/5 ( reviews)

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Book Synopsis microRNA: Medical Evidence by : Gaetano Santulli

Download or read book microRNA: Medical Evidence written by Gaetano Santulli. This book was released on 2015-12-11. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores microRNA function in a wide array of human disorders, providing a clinical basis for precision medicine and personalized therapies using these molecules. The twenty-one chapters, all authored by internationally-renowned experts, open with an introduction contextualizing microRNA manipulation within today’s initiatives towards precision medicine. The following chapters explore the clinical role of microRNAs in the diagnosis and treatment of metabolic and cardiovascular disorders, focusing on mitochondrial fitness, arterial hypertension, cardiovascular remodeling, cerebrovascular disease, pulmonary hypertension, diabetic kidney disease, and kidney transplantation. The subsequent chapters discuss the importance of microRNAs in the wound healing process and in skin disease, in the pathogenesis of allergy, in human ovulation, and in infection. The book concludes with chapters which outline the emerging role of microRNAS in doping and detail microRNA profiling. microRNA: Medical Evidence is an ideal companion to both microRNA: Basic Scienceand microRNA: Cancer. Taken together, these three books provide a state-of-the-art overview of this rapidly-expanding and fascinating field, from the molecular level to clinical practice. It will be invaluable to medical students, physicians, and researchers, as a complete and unique guide in the exploration of microRNA in basic science, cancer and clinical practice.

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