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MicroRNAs in Diseases and Disorders

2019-05-07 Science
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Release : 2019-05-07
Genre : Science
Kind : eBook
Book Rating : 811/5 ( reviews)

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Book Synopsis MicroRNAs in Diseases and Disorders by : Philip V Peplow

Download or read book MicroRNAs in Diseases and Disorders written by Philip V Peplow. This book was released on 2019-05-07. Available in PDF, EPUB and Kindle. Book excerpt: From pathology to treatment, MicroRNAs in Diseases and Disorders highlights the role of microRNAs (miRNAs) in the development and progression of a variety of diseases, including cancer, neurological disease, endocrine disease and autoimmune disease, and underscores the utilization of miRNA targets in the treatment of these conditions. Providing a comprehensive account, this book also includes the identification of miRNAs as diagnostic and prognostic biomarkers for disease, as well as evaluates translational value from clinical trials using synthesized and functionalized miRNA mimics and inhibitors. With a global contribution list and chapters from leading experts across the field, MicroRNAs in Diseases and Disorders is an invaluable reference to miRNA researchers and health professionals in a variety of disease areas in government, academia and industry. The book will also appeal to pharmaceutical and medicinal chemists with an interest in miRNA targeting therapeutics, as well as to advanced students in chemical biology and drug discovery.

MicroRNAs in Diseases and Disorders: Emerging Therapeutic Targets

2019-05-21 Medical
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Release : 2019-05-21
Genre : Medical
Kind : eBook
Book Rating : 948/5 ( reviews)

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Book Synopsis MicroRNAs in Diseases and Disorders: Emerging Therapeutic Targets by : Philip V Peplow

Download or read book MicroRNAs in Diseases and Disorders: Emerging Therapeutic Targets written by Philip V Peplow. This book was released on 2019-05-21. Available in PDF, EPUB and Kindle. Book excerpt: From pathology to treatment, MicroRNAs in Diseases and Disorders highlights the role of microRNAs (miRNAs) in the development and progression of a variety of diseases, including cancer, neurological disease, endocrine disease and autoimmune disease, and underscores the utilization of miRNA targets in the treatment of these conditions. Providing a comprehensive account, this book also includes the identification of miRNAs as diagnostic and prognostic biomarkers for disease, as well as evaluates translational value from clinical trials using synthesized and functionalized miRNA mimics and inhibitors. With a global contribution list and chapters from leading experts across the field, MicroRNAs in Diseases and Disorders is an invaluable reference to miRNA researchers and health professionals in a variety of disease areas in government, academia and industry. The book will also appeal to pharmaceutical and medicinal chemists with an interest in miRNA targeting therapeutics, as well as to advanced students in chemical biology and drug discovery.

Hormones, Metabolism and the Benefits of Exercise

2018-03-07 Science
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Release : 2018-03-07
Genre : Science
Kind : eBook
Book Rating : 907/5 ( reviews)

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Book Synopsis Hormones, Metabolism and the Benefits of Exercise by : Bruce Spiegelman

Download or read book Hormones, Metabolism and the Benefits of Exercise written by Bruce Spiegelman. This book was released on 2018-03-07. Available in PDF, EPUB and Kindle. Book excerpt: The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.

Current Perspectives in microRNAs (miRNA)

2008-09-12 Medical
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Release : 2008-09-12
Genre : Medical
Kind : eBook
Book Rating : 338/5 ( reviews)

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Book Synopsis Current Perspectives in microRNAs (miRNA) by : Shao-Yao Ying

Download or read book Current Perspectives in microRNAs (miRNA) written by Shao-Yao Ying. This book was released on 2008-09-12. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 97% of the human genome is the non-coding DNA, which varies from one species to another, and changes in these sequences are frequently noticed to manifest clinical and circumstantial malfunction. Numerous non-protein-coding genes are recently found to encode microRNAs, which are responsible for RNA-mediated gene silencing through RNA interference (RNAi)-like pathways. MicroRNAs (miRNAs), small single-stranded 17–25 nucleotide RNAs capable of interfering with intracellular messenger RNAs (mRNAs) that contain either complete or partial complementarity, are useful for the design of new therapies against cancer polymorphism and viral mutation. Currently over 1000 native miRNA species found in vertebrates and many more new miRNA homologs continue to be identified; however, most of their functions remain to be determined. In this book, many new perspectives of the miRNA research are reviewed and discussed, including their roles in stem cell maintenance, embryonic development, tissue differentiation, adult physiology, disease pathology, cancer research, viral infection, genetic engineering in plants, and utility in cosmetic applications. These new findings may not only provide significant insight into the various mechanisms of miRNAs but also offer a great opportunity in developing new therapeutic interventions.

MicroRNAs in Medicine

2013-10-30 Science
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Release : 2013-10-30
Genre : Science
Kind : eBook
Book Rating : 343/5 ( reviews)

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Book Synopsis MicroRNAs in Medicine by : Charles H. Lawrie

Download or read book MicroRNAs in Medicine written by Charles H. Lawrie. This book was released on 2013-10-30. Available in PDF, EPUB and Kindle. Book excerpt: MicroRNAs in Medicine provides an access point into the current literature on microRNA for both scientists and clinicians, with an up-to-date look at what is happening in the emerging field of microRNAs and their relevance to medicine. Each chapter is a comprehensive review, with descriptions of the latest microRNA research written by international leaders in their field. Opening with an introduction to what microRNAs are and how they function, the book goes on to explore the role of microRNAs in normal physiological functions, infectious diseases, non-infectious diseases, cancer, circulating microRNAs as non-invasive biomarkers, and finally their potential as novel therapeutics. Including background information on the field as well as reviews of the latest research breakthroughs, MicroRNAs in Medicine is a one-stop source of information to satisfy the specialists and non-specialists alike, appealing to students, researchers, and clinicians interested in understanding the potential of microRNAs in medicine and research.

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