Share

Mechanotransduction

2020-11-18 Technology & Engineering
Download Mechanotransduction PDF Online Free

Author :
Release : 2020-11-18
Genre : Technology & Engineering
Kind : eBook
Book Rating : 833/5 ( reviews)

GET EBOOK


Book Synopsis Mechanotransduction by : Paul A. Sundaram

Download or read book Mechanotransduction written by Paul A. Sundaram. This book was released on 2020-11-18. Available in PDF, EPUB and Kindle. Book excerpt: Mechanotransduction: Cell Signaling to Cell Response covers the cell machinery responsible for the process of mechanotransduction and the manner in which cells respond to an external mechanical stimulus. The effect of mechanical stimulus on individual cells and entire tissues is discussed, with an emphasis on the practical results of this physiological process. Mechanotransduction of stem cells and cancerous cells are also covered, along with future directions in this yet nascent field. This book gives insights on basic processes that occur (or may occur) in the human body as a result of the application of mechanical stimulus. It is ideal for both biomedical engineers and biologists, and is an ideal resource for teaching. It provides a current state of conceptual and practical aspects of the field and will enable students and professionals to venture further into this incipient area which is of fundamental importance to biomedical engineering and biology fields. Covers fundamental concepts of signaling in cells as a result of mechanical stimulus Includes the physiological results of mechanical stimulus on the human body Explores the advantages of mechanical loads on the human body

Mechanosensitivity and Mechanotransduction

2010-11-18 Science
Download Mechanosensitivity and Mechanotransduction PDF Online Free

Author :
Release : 2010-11-18
Genre : Science
Kind : eBook
Book Rating : 81X/5 ( reviews)

GET EBOOK


Book Synopsis Mechanosensitivity and Mechanotransduction by : Irina Kiseleva

Download or read book Mechanosensitivity and Mechanotransduction written by Irina Kiseleva. This book was released on 2010-11-18. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest findings in the field of research of mechanosensitivity and mechanotransduction in different cells and tissues. Mechanosensitivity and mechanotransduction of the heart and vascular cells, in the lung, in bone and joint tissues, in sensor systems and in blood cells are described in detail. This Volume focuses on molecular mechanisms of mechanosensitivity and mechanotransduction via cytoskeleton. Integrin-mediated mechanotransduction, the role of actin cytoskeleton and the role of other cytoskeletal elements are discussed. It contains a detailed description of several stretch-induced signaling cascades with multiple levels of crosstalk between different pathways. It contains a description of the role of nitric oxide in regulation of cardiac activity and in regulation of mechanically gated channels in the heart. In the heart mechanical signals are propagated into the intracellular space primarily via integrin-linked complexes, and are subsequently transmitted from cell to cell via paracrine signaling. Biochemical signals derived from mechanical stimuli activate both acute phosphorylation of signaling cascades, such as in the PI3K, FAK, and ILK pathways, and long-term morphological modii cations via intracellular cytoskeletal reorganization and extracellular matrix remodelling. Cellular and molecular effects of mechanical stretch on vascular cells are also discussed. This Volume highlights the role of mechanotransduction in the lung, in bone and joint tissues. For the first time mechanosensitivity and mechanotransduction in blood cells are discussed. It contains new insights into mechanosensitive K+ channels functioning in mouse B lymphocytes. This book is a unique collection of reviews outlining current knowledge and future developments in this rapidly growing field. Currently, investigations of the molecular mechanisms of mechanosensitivity and mechanotransduction are focused on several issues. The majority of studies investigate intracellular signaling pathways. Knowledge of the mechanisms which underlie these processes is necessary for understanding of the normal functioning of different organs and tissues and allows to predict changes, which arise due to alterations of their environment. Possibly such knowledge will allow the development of new methods of artificial intervention and therapies. This book brings up the problem closer to the experts in related medical and biological sciences as well as practicing doctors besides just presenting the latest achievements in the field.

Cellular Mechanotransduction

2014-07-31 Technology & Engineering
Download Cellular Mechanotransduction PDF Online Free

Author :
Release : 2014-07-31
Genre : Technology & Engineering
Kind : eBook
Book Rating : 467/5 ( reviews)

GET EBOOK


Book Synopsis Cellular Mechanotransduction by : Mohammad R. K. Mofrad

Download or read book Cellular Mechanotransduction written by Mohammad R. K. Mofrad. This book was released on 2014-07-31. Available in PDF, EPUB and Kindle. Book excerpt: "Mechanotransduction" is the term for the ability, first described by 19th-century anatomist Julius Wolff, of living tissues to sense mechanical stress and respond by tissue remodeling. More recently, the scope of mechanotransduction has been expanded to include the sensation of stress, its translation into a biochemical signal, and the sequence of biological responses it produces. This book looks at mechanotransduction in a more restricted sense, focusing on the process of stress sensing and transducing a mechanical force into a cascade of biochemical signals. This stress has become increasingly recognized as one of the primary and essential factors controlling biological functions, ultimately affecting the function of the cells, tissues, and organs. A primary goal of this broad book is also to help define the new field of mechanomics, which attempts to describe the complete mechanical state of a biological system.

Mechanosensitive Ion Channels

2007-10-06 Science
Download Mechanosensitive Ion Channels PDF Online Free

Author :
Release : 2007-10-06
Genre : Science
Kind : eBook
Book Rating : 268/5 ( reviews)

GET EBOOK


Book Synopsis Mechanosensitive Ion Channels by : Andre Kamkin

Download or read book Mechanosensitive Ion Channels written by Andre Kamkin. This book was released on 2007-10-06. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the latest data dealing with mechanosensitive channels research results. It was compiled by a group of internationally recognized scientists leading in the field of mechanosensitive ion channels or mechanically gated channels and signaling cascades research. Key problems of cell mechanobiology are also discussed. As a whole, the volume dwells on the major issues of mechanical stress influencing the ion channels and intracellular signaling pathways.

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades

2006-09-29 Medical
Download TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades PDF Online Free

Author :
Release : 2006-09-29
Genre : Medical
Kind : eBook
Book Rating : 847/5 ( reviews)

GET EBOOK


Book Synopsis TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades by : Wolfgang B. Liedtke, MD, PH.D.

Download or read book TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades written by Wolfgang B. Liedtke, MD, PH.D.. This book was released on 2006-09-29. Available in PDF, EPUB and Kindle. Book excerpt: Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st

You may also like...