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Cellular Mechanotransduction

2014-07-31 Technology & Engineering
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Release : 2014-07-31
Genre : Technology & Engineering
Kind : eBook
Book Rating : 467/5 ( reviews)

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Book Synopsis Cellular Mechanotransduction by : Mohammad R. K. Mofrad

Download or read book Cellular Mechanotransduction written by Mohammad R. K. Mofrad. This book was released on 2014-07-31. Available in PDF, EPUB and Kindle. Book excerpt: "Mechanotransduction" is the term for the ability, first described by 19th-century anatomist Julius Wolff, of living tissues to sense mechanical stress and respond by tissue remodeling. More recently, the scope of mechanotransduction has been expanded to include the sensation of stress, its translation into a biochemical signal, and the sequence of biological responses it produces. This book looks at mechanotransduction in a more restricted sense, focusing on the process of stress sensing and transducing a mechanical force into a cascade of biochemical signals. This stress has become increasingly recognized as one of the primary and essential factors controlling biological functions, ultimately affecting the function of the cells, tissues, and organs. A primary goal of this broad book is also to help define the new field of mechanomics, which attempts to describe the complete mechanical state of a biological system.

Mechanotransduction

2020-11-18 Technology & Engineering
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Release : 2020-11-18
Genre : Technology & Engineering
Kind : eBook
Book Rating : 833/5 ( reviews)

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Book Synopsis Mechanotransduction by : Paul A. Sundaram

Download or read book Mechanotransduction written by Paul A. Sundaram. This book was released on 2020-11-18. Available in PDF, EPUB and Kindle. Book excerpt: Mechanotransduction: Cell Signaling to Cell Response covers the cell machinery responsible for the process of mechanotransduction and the manner in which cells respond to an external mechanical stimulus. The effect of mechanical stimulus on individual cells and entire tissues is discussed, with an emphasis on the practical results of this physiological process. Mechanotransduction of stem cells and cancerous cells are also covered, along with future directions in this yet nascent field. This book gives insights on basic processes that occur (or may occur) in the human body as a result of the application of mechanical stimulus. It is ideal for both biomedical engineers and biologists, and is an ideal resource for teaching. It provides a current state of conceptual and practical aspects of the field and will enable students and professionals to venture further into this incipient area which is of fundamental importance to biomedical engineering and biology fields. Covers fundamental concepts of signaling in cells as a result of mechanical stimulus Includes the physiological results of mechanical stimulus on the human body Explores the advantages of mechanical loads on the human body

Cellular Mechanotransduction

2014-07-31 Technology & Engineering
Download Cellular Mechanotransduction PDF Online Free

Author :
Release : 2014-07-31
Genre : Technology & Engineering
Kind : eBook
Book Rating : 476/5 ( reviews)

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Book Synopsis Cellular Mechanotransduction by : Mohammad R. K. Mofrad

Download or read book Cellular Mechanotransduction written by Mohammad R. K. Mofrad. This book was released on 2014-07-31. Available in PDF, EPUB and Kindle. Book excerpt: 'Mechanotransduction' is the term for the ability, first described by 19th-century anatomist Julius Wolff, of living tissues to sense mechanical stress and respond by tissue remodeling. More recently, the scope of mechanotransduction has been expanded to include the sensation of stress, its translation into a biochemical signal, and the sequence of biological responses it produces. This book looks at mechanotransduction in a more restricted sense, focusing on the process of stress sensing and transducing a mechanical force into a cascade of biochemical signals. This stress has become increasingly recognized as one of the primary and essential factors controlling biological functions, ultimately affecting the function of the cells, tissues, and organs. A primary goal of this broad book is also to help define the new field of mechanomics, which attempts to describe the complete mechanical state of a biological system.

Cellular Mechanotransduction Mechanisms in Cardiovascular and Fibrotic Diseases

2021-10-22 Science
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Release : 2021-10-22
Genre : Science
Kind : eBook
Book Rating : 240/5 ( reviews)

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Book Synopsis Cellular Mechanotransduction Mechanisms in Cardiovascular and Fibrotic Diseases by :

Download or read book Cellular Mechanotransduction Mechanisms in Cardiovascular and Fibrotic Diseases written by . This book was released on 2021-10-22. Available in PDF, EPUB and Kindle. Book excerpt: Endothelial Signaling, Mechanotransduction, Vascular Biology and Atherosclerosis, Volume 87, the latest release in the Current Topics in Membranes series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in "Current Topics in Membranes" series Updated release includes the latest information on Endothelial Signaling, Mechanotransduction, Vascular Biology and Atherosclerosis

Mechanosensitivity and Mechanotransduction

2010-11-18 Science
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Release : 2010-11-18
Genre : Science
Kind : eBook
Book Rating : 81X/5 ( reviews)

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Book Synopsis Mechanosensitivity and Mechanotransduction by : Irina Kiseleva

Download or read book Mechanosensitivity and Mechanotransduction written by Irina Kiseleva. This book was released on 2010-11-18. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest findings in the field of research of mechanosensitivity and mechanotransduction in different cells and tissues. Mechanosensitivity and mechanotransduction of the heart and vascular cells, in the lung, in bone and joint tissues, in sensor systems and in blood cells are described in detail. This Volume focuses on molecular mechanisms of mechanosensitivity and mechanotransduction via cytoskeleton. Integrin-mediated mechanotransduction, the role of actin cytoskeleton and the role of other cytoskeletal elements are discussed. It contains a detailed description of several stretch-induced signaling cascades with multiple levels of crosstalk between different pathways. It contains a description of the role of nitric oxide in regulation of cardiac activity and in regulation of mechanically gated channels in the heart. In the heart mechanical signals are propagated into the intracellular space primarily via integrin-linked complexes, and are subsequently transmitted from cell to cell via paracrine signaling. Biochemical signals derived from mechanical stimuli activate both acute phosphorylation of signaling cascades, such as in the PI3K, FAK, and ILK pathways, and long-term morphological modii cations via intracellular cytoskeletal reorganization and extracellular matrix remodelling. Cellular and molecular effects of mechanical stretch on vascular cells are also discussed. This Volume highlights the role of mechanotransduction in the lung, in bone and joint tissues. For the first time mechanosensitivity and mechanotransduction in blood cells are discussed. It contains new insights into mechanosensitive K+ channels functioning in mouse B lymphocytes. This book is a unique collection of reviews outlining current knowledge and future developments in this rapidly growing field. Currently, investigations of the molecular mechanisms of mechanosensitivity and mechanotransduction are focused on several issues. The majority of studies investigate intracellular signaling pathways. Knowledge of the mechanisms which underlie these processes is necessary for understanding of the normal functioning of different organs and tissues and allows to predict changes, which arise due to alterations of their environment. Possibly such knowledge will allow the development of new methods of artificial intervention and therapies. This book brings up the problem closer to the experts in related medical and biological sciences as well as practicing doctors besides just presenting the latest achievements in the field.

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