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Ionic Actions on Vascular Smooth Muscle

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Release : 2012-12-06
Genre : Medical
Kind : eBook
Book Rating : 27X/5 ( reviews)

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Book Synopsis Ionic Actions on Vascular Smooth Muscle by : E. Betz

Download or read book Ionic Actions on Vascular Smooth Muscle written by E. Betz. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the contributions and discussions of the second symposium on vascular smooth muscles held in Ttibingen in February, 1976. It provides an up-to-date review of the role of ions in the trans mission of signals from the perivascular space to the contractile ele ments of the smooth muscle cells. The various aspects are mainly discussed from a functional point of view and only few contributions concern the morphologic variations of cells .during varying ion activity. Special emphasis was placed on the significance of ion variations in the cerebral tissue and their rela tion to metabolic and nervous control of the brain vessels. It could be seen in this symposium that new techniques enabled the in vestigators to make considerable progress in the understanding of the actions and the interactions of ions on the membranes and on the inter nal structures of the smooth muscle cells if one compares the findings with the results of the previous symposium held in Ttibingen in 1972. It became evident that the insight into ionic actions enables the de velopment of powerful tools to be utilized in future therapy of dis turbances of local blood flow regulation. The participants of the symposium render thanks to the Dr. Thiemann GmbH in Ltinen, which supported the symposium and this publication in a generous way. Finally it is a pleasure of the Editor to thank the members of the Physiological Institute of Ttibingen for their encouragement in the ar rangement of the meeting.

Ionic Actions on Vascular Smooth Muscles : with Special Regard to Brain Vessels (contributions and Discussions).

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Release : 1976
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Book Synopsis Ionic Actions on Vascular Smooth Muscles : with Special Regard to Brain Vessels (contributions and Discussions). by : Symposium on Vascular Smooth Muscles (2d : 1976 : Tubingen)

Download or read book Ionic Actions on Vascular Smooth Muscles : with Special Regard to Brain Vessels (contributions and Discussions). written by Symposium on Vascular Smooth Muscles (2d : 1976 : Tubingen). This book was released on 1976. Available in PDF, EPUB and Kindle. Book excerpt:

Ionic Actions on Vascular Smooth Muscle with Special Regard to Brain Vessels

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Release : 1976
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Book Synopsis Ionic Actions on Vascular Smooth Muscle with Special Regard to Brain Vessels by : Symposium on Vascular Smooth Muscles (2nd: 1976: Tubingen)

Download or read book Ionic Actions on Vascular Smooth Muscle with Special Regard to Brain Vessels written by Symposium on Vascular Smooth Muscles (2nd: 1976: Tubingen). This book was released on 1976. Available in PDF, EPUB and Kindle. Book excerpt:

Vascular Smooth Muscle: Metabolic, Ionic, and Contractile Mechanisms

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Release : 2012-12-02
Genre : Medical
Kind : eBook
Book Rating : 877/5 ( reviews)

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Book Synopsis Vascular Smooth Muscle: Metabolic, Ionic, and Contractile Mechanisms by : M.F. III Crass

Download or read book Vascular Smooth Muscle: Metabolic, Ionic, and Contractile Mechanisms written by M.F. III Crass. This book was released on 2012-12-02. Available in PDF, EPUB and Kindle. Book excerpt: Vascular Smooth Muscle: Metabolic, Ionic, and Contractile Mechanisms addresses the vascular smooth muscle function by describing plasma lipoprotein structure, synthesis, and transport in relation to the concepts of altered vascular smooth muscle lipid metabolism leading to the genesis of atherosclerotic disease. This book is organized into six chapters and begins with an introduction to the complexities of energy metabolism and how metabolic events can be correlated with a simultaneous quantitative assessment of smooth muscle mechanics and the contractile machinery at the molecular level. The next two chapters offer the reader a view of smooth muscle membrane properties in terms of the distribution, transport, and metabolic control of electrolytes and specific aspects of ion conductance and electrical activity. This text also explains how smooth muscle cells regulate their contractile activity through regulation of calcium ion fluxes and the interaction, at the molecular level, of calcium ions with regulatory proteins associated with the contractile apparatus. Reference is made to the relation of possible anomalies in cellular or subcellular smooth muscle metabolic and/or ionic events to the bases of certain types of vascular disease. A chapter that examines the events leading to vascular pathology in the form of atherogenesis concludes the book. This book is intended for researchers and clinicians engaged in the study of smooth muscle and related areas.

The Endothelium

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Release : 2011
Genre : Science
Kind : eBook
Book Rating : 230/5 ( reviews)

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Book Synopsis The Endothelium by : Michel Félétou

Download or read book The Endothelium written by Michel Félétou. This book was released on 2011. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References

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