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Glutathione System and Oxidative Stress in Health and Disease

2020-08-26 Science
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Release : 2020-08-26
Genre : Science
Kind : eBook
Book Rating : 251/5 ( reviews)

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Book Synopsis Glutathione System and Oxidative Stress in Health and Disease by :

Download or read book Glutathione System and Oxidative Stress in Health and Disease written by . This book was released on 2020-08-26. Available in PDF, EPUB and Kindle. Book excerpt: The imbalance between the production of reactive oxygen species (ROS) and antioxidant defenses determines a state known as oxidative stress. Higher levels of pro-oxidants compared to antioxidant defenses may generate oxidative damage, which, in turn, may lead to modifications in cellular proteins, lipids, and DNA, reducing functional capacity and increasing the risk of diseases. Nevertheless, the clearance of harmful reactive chemical species is achieved by the antioxidant defense systems. These protection systems are referred to as the first and second lines of defense and comprise the classic antioxidants, enzymatic and nonenzymatic defenses, including glutathione. This book presents and discusses the advancement of research on health and diseases and their underlying mechanisms, exploring mainly aspects related to the glutathione antioxidant system.

Glutathione Peroxidase in Health and Diseases

2019 Science
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Release : 2019
Genre : Science
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Glutathione Peroxidase in Health and Diseases by : Eren Sarikaya

Download or read book Glutathione Peroxidase in Health and Diseases written by Eren Sarikaya. This book was released on 2019. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this study is to give information to readers about the importance of glutathione peroxidase. The physiopathology of most diseases is not fully elucidated currently; however, in many epidemiological studies, there are limited studies indicating the relationship between low levels of glutathione peroxidase status and the rise of cancer risk in many types of cancer. Anytime, situations in case of the distortion due to imbalance between enzymatic and nonenzymatic antioxidants and oxidants which lost one of paired electrons in the atomic level mean reactive oxygen species (ROS) withal reactive nitrogen species (RNS) in favor of oxidants that are related to oxidative stress. The possible mechanisms of glutathione peroxidase have been reviewed using the major findings of more than 1000 papers related to the ROS, glutathione peroxidase, and oxidative stress. Oxidative stress plays an important role in the occurrence and development of most diseases in both animal and human studies. Moreover, antioxidants have protective effects against nearly 50 disease pathogenesis. Oxidative stress, which occurs as an outcome of lipid peroxidation, concurrently may have a key importance in the phase of carcinogenesis occurring with a multistage course devoted to environmental toxicity and in cancer pathogenesis.

Glutathione in Health and Disease

2018-10-31 Science
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Release : 2018-10-31
Genre : Science
Kind : eBook
Book Rating : 751/5 ( reviews)

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Book Synopsis Glutathione in Health and Disease by : Pinar Erkekoglu

Download or read book Glutathione in Health and Disease written by Pinar Erkekoglu. This book was released on 2018-10-31. Available in PDF, EPUB and Kindle. Book excerpt: Reduced glutathione (GSH) is the most important thiol in living organisms. It is the key component of antioxidant system and serves as a free radical scavenger. There is a cycle of GSH in biological systems and this cycle provides higher intracellular levels of GSH. GSH depletion and apparent oxidative stress may cause toxicity and can affect the general well-being of the organism. GSH was shown to be preventive against aging, cancer, heart disease, infections and dementia. This book is mainly focused on GSH in health and disease. The readers will gain qualified scientific knowledge on the diverse functions of GSH, the importance of GSH status against oxidative stress and the interaction between GSH and nervous system-related infections from this book.

Trace Elements and Minerals in Health and Longevity

2018-11-13 Medical
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Release : 2018-11-13
Genre : Medical
Kind : eBook
Book Rating : 428/5 ( reviews)

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Book Synopsis Trace Elements and Minerals in Health and Longevity by : Marco Malavolta

Download or read book Trace Elements and Minerals in Health and Longevity written by Marco Malavolta. This book was released on 2018-11-13. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the role of trace elements in health and longevity, pursuing a biogerontological approach. It offers essential information on the impact of trace elements on molecular and physiological processes of aging, and on their impact on health in connection with aging. The major topics covered in its 11 chapters, each dedicated to a specific trace element or mineral, are: a) Role of the element in species longevity, b) Recommended intake for longevity in animal species and in the elderly, c) Deficiency and age-related disease, d) Excess/toxicity and age-related disease, and e) Interactions with drugs prescribed in the elderly. Clinical, animal and other laboratory models of interest in aging are included, which enable a more in-depth analysis to be made. The respective chapters are a mixture of overviews and more in-depth reviews in which the mechanisms of aging are described from the point of view of their specific interactions with trace elements and minerals.

Advances in Nutritional Research

2013-06-29 Science
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Release : 2013-06-29
Genre : Science
Kind : eBook
Book Rating : 48X/5 ( reviews)

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Book Synopsis Advances in Nutritional Research by : H. Draper

Download or read book Advances in Nutritional Research written by H. Draper. This book was released on 2013-06-29. Available in PDF, EPUB and Kindle. Book excerpt: The third volume of Advances in Nutritional Research continues the precedent set in previous volumes of providing authoritative reviews on the current state of knowledge with respect to major topics of ongoing nutritional research. This series is designed to be of value to investigators engaged in fundamental research as well as to those involved in its application to problems in human and animal nutrition. This volume contains three chapters on recent developments in research on inorganic elements, including a review, by F. H. Nielsen, of the evidence for a requirement for additional trace elements; a conspectus, by C. E. Casey and K. M. Hambidge, on the occurrence of trace element deficiencies in man; and a description, by M. Janghorbani and V. R. Young, of new methods of assessing the bioavailability of minerals in the diet. There are also three chapters on current topics of lipid research. One (by F. D. Sauer) is devoted to the cardiopathic effects of certain dietary monoenoic fatty acids, another (by C. Galli) to the influence of diet on prostaglandin synthesis, and the third (by H. 0. Bang and J. Dyerberg) to an analysis of the role of the unusual polyunsaturated fatty acids found in marine oils in the prevention of ischemic heart disease.

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