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Essentials of Single-Cell Analysis

2016-01-21 Technology & Engineering
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Release : 2016-01-21
Genre : Technology & Engineering
Kind : eBook
Book Rating : 184/5 ( reviews)

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Book Synopsis Essentials of Single-Cell Analysis by : Fan-Gang Tseng

Download or read book Essentials of Single-Cell Analysis written by Fan-Gang Tseng. This book was released on 2016-01-21. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of single-cell isolation, separation, injection, lysis and dynamics analysis as well as a study of their heterogeneity using different miniaturized devices. As an important part of single-cell analysis, different techniques including electroporation, microinjection, optical trapping, optoporation, rapid electrokinetic patterning and optoelectronic tweezers are described in detail. It presents different fluidic systems (e.g. continuous micro/nano-fluidic devices, microfluidic cytometry) and their integration with sensor technology, optical and hydrodynamic stretchers etc., and demonstrates the applications of single-cell analysis in systems biology, proteomics, genomics, epigenomics, cancer transcriptomics, metabolomics, biomedicine and drug delivery systems. It also discusses the future challenges for single-cell analysis, including the advantages and limitations. This book is enjoyable reading material while at the same time providing essential information to scientists in academia and professionals in industry working on different aspects of single-cell analysis. Dr. Fan-Gang Tseng is a Distinguished Professor of Engineering and System Science at the National Tsing Hua University, Taiwan. Dr. Tuhin Subhra Santra is a Research Associate at the California Nano Systems Institute, University of California at Los Angeles, USA.

Essentials of Single-Cell Analysis

2017-06
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Release : 2017-06
Genre :
Kind : eBook
Book Rating : 211/5 ( reviews)

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Book Synopsis Essentials of Single-Cell Analysis by : John Maclane

Download or read book Essentials of Single-Cell Analysis written by John Maclane. This book was released on 2017-06. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of single-cell isolation, separation, injection, lysis and dynamics analysis as well as a study of their heterogeneity using different miniaturized devices. As an important part of single-cell analysis, different techniques including electroporation, microinjection, optical trapping, optoporation, rapid electrokinetic patterning and optoelectronic tweezers are described in detail. It presents different fluidic systems (e.g. continuous micro/nano-fluidic devices, microfluidic cytometry) and their integration with sensor technology, optical and hydrodynamic stretchers etc., and demonstrates the applications of single-cell analysis in systems biology, proteomics, genomics, epigenomics, cancer transcriptomics, metabolomics, biomedicine and drug delivery systems. It also discusses the future challenges for single-cell analysis, including the advantages and limitations.

Computational Methods for Single-Cell Data Analysis

2019-02-14 Science
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Release : 2019-02-14
Genre : Science
Kind : eBook
Book Rating : 566/5 ( reviews)

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Book Synopsis Computational Methods for Single-Cell Data Analysis by : Guo-Cheng Yuan

Download or read book Computational Methods for Single-Cell Data Analysis written by Guo-Cheng Yuan. This book was released on 2019-02-14. Available in PDF, EPUB and Kindle. Book excerpt: This detailed book provides state-of-art computational approaches to further explore the exciting opportunities presented by single-cell technologies. Chapters each detail a computational toolbox aimed to overcome a specific challenge in single-cell analysis, such as data normalization, rare cell-type identification, and spatial transcriptomics analysis, all with a focus on hands-on implementation of computational methods for analyzing experimental data. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Methods for Single-Cell Data Analysis aims to cover a wide range of tasks and serves as a vital handbook for single-cell data analysis.

High-Dimensional Single Cell Analysis

2014-04-22 Medical
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Release : 2014-04-22
Genre : Medical
Kind : eBook
Book Rating : 27X/5 ( reviews)

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Book Synopsis High-Dimensional Single Cell Analysis by : Harris G. Fienberg

Download or read book High-Dimensional Single Cell Analysis written by Harris G. Fienberg. This book was released on 2014-04-22. Available in PDF, EPUB and Kindle. Book excerpt: This volume highlights the most interesting biomedical and clinical applications of high-dimensional flow and mass cytometry. It reviews current practical approaches used to perform high-dimensional experiments and addresses key bioinformatic techniques for the analysis of data sets involving dozens of parameters in millions of single cells. Topics include single cell cancer biology; studies of the human immunome; exploration of immunological cell types such as CD8+ T cells; decipherment of signaling processes of cancer; mass-tag cellular barcoding; analysis of protein interactions by proximity ligation assays; Cytobank, a platform for the analysis of cytometry data; computational analysis of high-dimensional flow cytometric data; computational deconvolution approaches for the description of intracellular signaling dynamics and hyperspectral cytometry. All 10 chapters of this book have been written by respected experts in their fields. It is an invaluable reference book for both basic and clinical researchers.

Single Cell Analysis

2017-04-18 Technology & Engineering
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Release : 2017-04-18
Genre : Technology & Engineering
Kind : eBook
Book Rating : 996/5 ( reviews)

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Book Synopsis Single Cell Analysis by : J. Paul Robinson

Download or read book Single Cell Analysis written by J. Paul Robinson. This book was released on 2017-04-18. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the current state of the art in single cell analysis, an area that involves many fields of science – from clinical hematology, functional analysis and drug screening, to platelet and microparticle analysis, marine biology and fundamental cancer research. This book brings together an eclectic group of current applications, all of which have a significant impact on our current state of knowledge. The authors of these chapters are all pioneering researchers in the field of single cell analysis. The book will not only appeal to those readers more focused on clinical applications, but also those interested in highly technical aspects of the technologies. All of the technologies identified utilize unique applications of photon detection systems.

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