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Drug Resistance in Breast Cancer – Mechanisms and Approaches to Overcome Chemoresistance

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Release : 2023-02-03
Genre : Medical
Kind : eBook
Book Rating : 654/5 ( reviews)

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Book Synopsis Drug Resistance in Breast Cancer – Mechanisms and Approaches to Overcome Chemoresistance by : Maria Rosaria De Miglio

Download or read book Drug Resistance in Breast Cancer – Mechanisms and Approaches to Overcome Chemoresistance written by Maria Rosaria De Miglio. This book was released on 2023-02-03. Available in PDF, EPUB and Kindle. Book excerpt:

Overcoming Breast Cancer Therapy Resistance

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Kind : eBook
Book Rating : 603/5 ( reviews)

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Book Synopsis Overcoming Breast Cancer Therapy Resistance by : Zodwa Dlamini

Download or read book Overcoming Breast Cancer Therapy Resistance written by Zodwa Dlamini. This book was released on . Available in PDF, EPUB and Kindle. Book excerpt:

Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance

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Release : 2020-11-17
Genre : Science
Kind : eBook
Book Rating : 116/5 ( reviews)

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Book Synopsis Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance by : Andrew Freywald

Download or read book Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance written by Andrew Freywald. This book was released on 2020-11-17. Available in PDF, EPUB and Kindle. Book excerpt: Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance, Volume 12, discusses new approaches that are being undertaken to counteract tumor plasticity, understand and tackle the interactions with the microenvironment, and disrupt the rewiring of malignant cells or bypass biological mechanism of resistance by using targeted radionuclide therapies. This book provides a unique opportunity to the reader to understand the fundamental causes of drug resistance and how different approaches are applied. It is a one-stop-shop to understand why it is so difficult to treat cancer, and why only a very few patients respond to therapy and a significant portion develop resistance. Despite a rapid development of more effective anti-cancer drugs and combination therapies, cancer remains the leading cause of lethality in the developed world. The main reason for this is the ability of heterogeneous subpopulations of tumor cells interacting with constantly evolving tumor microenvironment to resist elimination and eventually, trigger cancer relapse. In this book, experts review current concepts explaining molecular and biological mechanisms of cancer drug resistance and discussing advancing approaches for overcoming these therapeutic challenges. Provides the most updated knowledge on the mechanisms of cancer drug resistance and the emerging therapeutic approaches reviewed by experts in the field Brings detailed analyses of most important recently reported developments related to drug resistance and their relevance to overcoming it in cancer patients Discusses in-depth molecular mechanisms and novel concepts of cancer resistance to conventional and advanced therapies

Drug Resistance in Cancer: Mechanisms and Strategies

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Kind : eBook
Book Rating : 667/5 ( reviews)

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Book Synopsis Drug Resistance in Cancer: Mechanisms and Strategies by : Sameer Ullah Khan

Download or read book Drug Resistance in Cancer: Mechanisms and Strategies written by Sameer Ullah Khan. This book was released on . Available in PDF, EPUB and Kindle. Book excerpt:

Cancer Drug Resistance

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Release : 2007-11-09
Genre : Medical
Kind : eBook
Book Rating : 359/5 ( reviews)

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Book Synopsis Cancer Drug Resistance by : Beverly A. Teicher

Download or read book Cancer Drug Resistance written by Beverly A. Teicher. This book was released on 2007-11-09. Available in PDF, EPUB and Kindle. Book excerpt: Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy. Highlights include new insights into resistance to antiangiogenic therapies, oncogenes and tumor suppressor genes in therapeutic resistance, cancer stem cells, and the development of more effective therapies. There are also new findings on tumor immune escape mechanisms, gene amplification in drug resistance, the molecular determinants of multidrug resistance, and resistance to taxanes and Herceptin.

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