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DNA Microarrays: Gene Expression Applications

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Author :
Release : 2013-12-01
Genre : Medical
Kind : eBook
Book Rating : 174/5 ( reviews)

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Book Synopsis DNA Microarrays: Gene Expression Applications by : B.R. Jordan

Download or read book DNA Microarrays: Gene Expression Applications written by B.R. Jordan. This book was released on 2013-12-01. Available in PDF, EPUB and Kindle. Book excerpt: This complete and practical manual on expression measurement using DNA arrays covers the existing methods (from nylon macroarrays to oligonucleotide chips) and includes detailed protocols. It has been written by practising scientists who have experienced the difficulties involved in actually using microarrays, and provides helpful advice and hints on setting up these powerful but sometimes tricky methods. Software, data mining procedures and probable future developments, which should be useful to any practising scientist interested in expression measurement, are also covered in this book.

DNA Microarrays

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Author :
Release : 2001
Genre : Science
Kind : eBook
Book Rating : 077/5 ( reviews)

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Book Synopsis DNA Microarrays by : Bertrand Jordan

Download or read book DNA Microarrays written by Bertrand Jordan. This book was released on 2001. Available in PDF, EPUB and Kindle. Book excerpt: This complete and practical manual on expression measurement using DNA arrays covers the existing methods (from nylon macroarrays to oligonucleotide chips) and includes detailed protocols. It has been written by practising scientists who have experienced the difficulties involved in actually using microarrays, and provides helpful advice and hints on setting up these powerful but sometimes tricky methods. Software, data mining procedures and probable future developments, which should be useful to any practising scientist interested in expression measurement, are also covered in this book. It also provides detailed protocols as well as many helpful hints to achieve experimental success and to avoid pitfalls.

Microarray Technology Through Applications

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Author :
Release : 2007-06-11
Genre : Science
Kind : eBook
Book Rating : 732/5 ( reviews)

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Book Synopsis Microarray Technology Through Applications by : Francesco Falciani

Download or read book Microarray Technology Through Applications written by Francesco Falciani. This book was released on 2007-06-11. Available in PDF, EPUB and Kindle. Book excerpt: Microarray Technology Through Applications provides the reader with an understanding, from an applications perspective, of the diverse range of concepts required to master the experimental and data analysis aspects of microarray technology. The first chapter is a concise introduction to the technology and provides the theoretical background required to understand the subsequent sections. The following chapters are a series of case studies representative of the most general and important applications of microarray technology, including CGH, analysis of gene expression, SNP arrays and protein arrays. The case studies are written by experts in the field and describe prototypic projects, indicating how to generalize the approach to similar studies. There are detailed step-by-step protocols describing the specific experimental and data analysis protocols mentioned in the case study section. There is also information on printing glass DNA microarray slides and data interpretation. Colour figures and data sets are provided on the website at http://www.garlandscience.com/9780415378536

Microarray Bioinformatics

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Author :
Release : 2019-05-22
Genre : Science
Kind : eBook
Book Rating : 410/5 ( reviews)

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Book Synopsis Microarray Bioinformatics by : Verónica Bolón-Canedo

Download or read book Microarray Bioinformatics written by Verónica Bolón-Canedo. This book was released on 2019-05-22. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive, interdisciplinary collection of the main, up-to-date methods, tools, and techniques for microarray data analysis, covering the necessary steps for the acquisition of the data, its preprocessing, and its posterior analysis. Featuring perspectives from biology, computer science, and statistics, the volume explores machine learning methods such as clustering, feature selection, classification, data normalization, and missing value imputation, as well as the statistical analysis of the data and the most popular computer tools to analyze microarray data. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice that will aid researchers in getting successful results. Cutting-edge and authoritative, Microarray Bioinformatics serves as an ideal guide for researchers and graduate students in bioinformatics, with basic knowledge in biology and computer science, and with a view to work with microarray datasets.

Microarray Technology and Its Applications

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Release : 2006-03-30
Genre : Medical
Kind : eBook
Book Rating : 783/5 ( reviews)

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Book Synopsis Microarray Technology and Its Applications by : Uwe R. Müller

Download or read book Microarray Technology and Its Applications written by Uwe R. Müller. This book was released on 2006-03-30. Available in PDF, EPUB and Kindle. Book excerpt: Ithasbeenstatedthatourknowledgedoublesevery20years,butthatmaybe an understatement when considering the Life Sciences. A series of discoveries and inventions have propelled our knowledge from the recognition that DNA isthegeneticmaterialtoabasicmolecularunderstandingofourselvesandthe living world around us in less than 50 years. Crucial to this rapid progress was thediscoveryofthedouble-helicalstructureofDNA,whichlaidthefoundation forallhybridizationbasedtechnologies. Thediscoveriesofrestrictionenzymes, ligases, polymerases, combined with key innovations in DNA synthesis and sequencing ushered in the era of biotechnologyas a new science with profound sociological and economic implications that are likely to have a dominating in?uence on the development of our society during this century. Given the process by which science builds on prior knowledge, it is perhaps unfair to single out a few inventions and credit them with having contributed most to thisavalancheofknowledge. Yet,therearesurelysomethatwillberecognized as having had a more profound impact than others, not just in the furthering of our scienti?c knowledge, but by leveraging commercial applications that provide a tangible return to our society. The now famous Polymerase Chain Reaction, or PCR, is surely one of those, as it has uniquely catalyzed molecular biology during the past 20 years, and continues to have a signi?cant impact on all areas that involve nucleic acids, ranging from molecular pathology to forensics. Ten years ago micro- ray technology emerged as a new and powerful tool to study nucleic acid - quences in a highly multiplexed manner, and has since found equally exciting and useful applications in the study of proteins, metabolites, toxins, viruses, whole cells and even tissues.

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