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Design and Analysis of DNA Microarray Investigations

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Release : 2006-05-09
Genre : Medical
Kind : eBook
Book Rating : 661/5 ( reviews)

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Book Synopsis Design and Analysis of DNA Microarray Investigations by : Richard M. Simon

Download or read book Design and Analysis of DNA Microarray Investigations written by Richard M. Simon. This book was released on 2006-05-09. Available in PDF, EPUB and Kindle. Book excerpt: The analysis of gene expression profile data from DNA micorarray studies are discussed in this book. It provides a review of available methods and presents it in a manner that is intelligible to biologists. It offers an understanding of the design and analysis of experiments utilizing microarrays to benefit scientists. It includes an Appendix tutorial on the use of BRB-ArrayTools and step by step analyses of several major datasets using this software which is available from the National Cancer Institute.

DNA Microarrays

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Author :
Release : 1999
Genre : Medical
Kind : eBook
Book Rating : 768/5 ( reviews)

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Book Synopsis DNA Microarrays by : Mark Schena

Download or read book DNA Microarrays written by Mark Schena. This book was released on 1999. Available in PDF, EPUB and Kindle. Book excerpt: DNA Microarrays: A Practical Approach is the first comprehensive overview of an exciting and powerful new technology. DNA microarrays, or biochips, are small glass chips embedded with ordered rows of DNA, providing a massive parallel platform for data gathering and representing a fundamental technical advance in biomedical research. Such biochips gather data at an unprecedented rate by enabling the use of advanced fabrication, detection, and data mining technologies. Written and edited by experts in the field, this book provides fascinating insight into this remarkable advancement. It opens with an introduction to the technology of DNA microarrays, emphasizing the methodological fundamentals of biochips, and continues with descriptions of the use of confocal scanning in microarray detection and techniques for the efficient cloning and screening of differentially expressed genes. The chapters address many topics, among them assay optimization, antisense scanning arrays, the manufacture of molecular arrays, and gene expression analysis. Also addressed are the uses of expression data in bioinformatics, of active microelectronic arrays for DNA hybridization analysis, and of microarray technology in pharmacogenomics. DNA Microarrays: A Practical Approach is ideal for researchers investigating patterns of gene expression (and the relationship with disease), and it is essential for any researcher interested in the use of biochips.

DNA Microarrays and Related Genomics Techniques

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Release : 2005-11-14
Genre : Mathematics
Kind : eBook
Book Rating : 790/5 ( reviews)

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Book Synopsis DNA Microarrays and Related Genomics Techniques by : David B. Allison

Download or read book DNA Microarrays and Related Genomics Techniques written by David B. Allison. This book was released on 2005-11-14. Available in PDF, EPUB and Kindle. Book excerpt: Considered highly exotic tools as recently as the late 1990s, microarrays are now ubiquitous in biological research. Traditional statistical approaches to design and analysis were not developed to handle the high-dimensional, small sample problems posed by microarrays. In just a few short years the number of statistical papers providing approaches

A Biologist's Guide to Analysis of DNA Microarray Data

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Author :
Release : 2011-09-23
Genre : Science
Kind : eBook
Book Rating : 180/5 ( reviews)

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Book Synopsis A Biologist's Guide to Analysis of DNA Microarray Data by : Steen Knudsen

Download or read book A Biologist's Guide to Analysis of DNA Microarray Data written by Steen Knudsen. This book was released on 2011-09-23. Available in PDF, EPUB and Kindle. Book excerpt: A great introductory book that details reliable approaches to problems met in standard microarray data analyses. It provides examples of established approaches such as cluster analysis, function prediction, and principle component analysis. Discover real examples to illustrate the key concepts of data analysis. Written for those without any advanced background in math, statistics, or computer sciences, this book is essential for anyone interested in harnessing the immense potential of microarrays in biology and medicine.

Guide to Analysis of DNA Microarray Data

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Release : 2005-03-04
Genre : Science
Kind : eBook
Book Rating : 26X/5 ( reviews)

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Book Synopsis Guide to Analysis of DNA Microarray Data by : Steen Knudsen

Download or read book Guide to Analysis of DNA Microarray Data written by Steen Knudsen. This book was released on 2005-03-04. Available in PDF, EPUB and Kindle. Book excerpt: Written for biologists and medical researchers who don't have any special training in data analysis and statistics, Guide to Analysis of DNA Microarray Data, Second Edition begins where DNA array equipment leaves off: the image produced by the microarray. The text deals with the questions that arise starting at this point, providing an introduction to microarray technology, then moving on to image analysis, data analysis, cluster analysis, and beyond. With all chapters rewritten, updated, and expanded to include the latest generation of technology and methods, Guide to Analysis of DNA Microarray Data, Second Edition offers practitioners reliable information using concrete examples and a clear, comprehensible style. This Second Edition features entirely new chapters on: * Image analysis * Experiment design * Automated analysis, integrated analysis, and systems biology * Interpretation of results Intended for readers seeking practical applications, this text covers a broad spectrum of proven approaches in this rapidly growing technology. Additional features include further reading suggestions for each chapter, as well as a thorough review of available analysis software.

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