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Coordinating Organismal Physiology Through the Unfolded Protein Response

2018-04-18 Medical
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Release : 2018-04-18
Genre : Medical
Kind : eBook
Book Rating : 303/5 ( reviews)

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Book Synopsis Coordinating Organismal Physiology Through the Unfolded Protein Response by : R. Luke Wiseman

Download or read book Coordinating Organismal Physiology Through the Unfolded Protein Response written by R. Luke Wiseman. This book was released on 2018-04-18. Available in PDF, EPUB and Kindle. Book excerpt: This volume reviews the current research focused on the functional importance of unfolded protein response (UPR) signaling in the context of health and disease. The chapters present cutting-edge work describing the diverse functions of UPR signaling critical for regulating cellular and organismal physiology under physiologic and pathologic conditions. Written by internationally respected scientists, this volume is designed to provide a broad view of the diverse functional importance of UPR, and as such appeals to clinicians and academic researchers alike.

The Unfolded Protein Response and Cellular Stress

2011 Cell physiology
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Release : 2011
Genre : Cell physiology
Kind : eBook
Book Rating : 28X/5 ( reviews)

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Book Synopsis The Unfolded Protein Response and Cellular Stress by : P. Michael Conn

Download or read book The Unfolded Protein Response and Cellular Stress written by P. Michael Conn. This book was released on 2011. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights. This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights

The Unfolded Protein Response

2022-01-06 Science
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Release : 2022-01-06
Genre : Science
Kind : eBook
Book Rating : 311/5 ( reviews)

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Book Synopsis The Unfolded Protein Response by : Roberto Pérez-Torrado

Download or read book The Unfolded Protein Response written by Roberto Pérez-Torrado. This book was released on 2022-01-06. Available in PDF, EPUB and Kindle. Book excerpt: This volume is divided in six section covering the most experimental approaches involved in the study of the unfolded protein response (UPR) pathway. Chapters detail determination of unfolded protein levels, methods to study UPR signal transmission, analysing the outcomes of the UPR pathway activation, UPR studies in mammalian models, UPR in alternative models, and UPR and disease. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, The Unfolded Protein Response: Methods and Protocols aims to describe key methods and approaches used in the study of the UPR pathway and its complex cellular implications. Chapter 6 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Drug Targets in Cellular Processes of Cancer: From Nonclinical to Preclinical Models

2020-09-30 Medical
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Release : 2020-09-30
Genre : Medical
Kind : eBook
Book Rating : 86X/5 ( reviews)

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Book Synopsis Drug Targets in Cellular Processes of Cancer: From Nonclinical to Preclinical Models by : Hardeep Singh Tuli

Download or read book Drug Targets in Cellular Processes of Cancer: From Nonclinical to Preclinical Models written by Hardeep Singh Tuli. This book was released on 2020-09-30. Available in PDF, EPUB and Kindle. Book excerpt: This book explores potential cellular drug targets for cancer therapy. The first couple of chapters describe conventional treatment (radiotherapy, chemotherapy, and immunotherapy) & detection (biosensors) strategies for cancer. In contrast, the subsequent chapters address the role of cyclin-dependent kinases and cell cycle regulatory proteins in the growth of cancer cells and their potential as target for cancer treatment. The book then discusses the regulation of various pro-apoptotic and anti-apoptotic proteins via chemotherapeutic drugs. In addition, it examines the molecular mechanisms that are critical for mediating autophagic cell death in cancer cells. It subsequently reviews the role of reactive oxygen (ROS) species during carcinogenesis and during chemotherapy, and the potential of anti-inflammatory routes for the development of new therapeutic modulators. Lastly, it describes therapeutic strategies that target the tumor microenvironment and various angiogenic pathways for the treatment of cancer and to develop personalized medicine. Given its scope, the book is valuable resource for oncologists, cancer researchers, clinicians, and pharmaceutical industry personnel.

Regulation of Endoplasmic Reticulum and Mitochondria in Cellular Homeostasis

2022-10-07 Science
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Release : 2022-10-07
Genre : Science
Kind : eBook
Book Rating : 893/5 ( reviews)

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Book Synopsis Regulation of Endoplasmic Reticulum and Mitochondria in Cellular Homeostasis by : Yongye Huang

Download or read book Regulation of Endoplasmic Reticulum and Mitochondria in Cellular Homeostasis written by Yongye Huang. This book was released on 2022-10-07. Available in PDF, EPUB and Kindle. Book excerpt:

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