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Chemical and Functional Genomic Approaches to Stem Cell Biology and Regenerative Medicine

2008-02-08 Medical
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Release : 2008-02-08
Genre : Medical
Kind : eBook
Book Rating : 121/5 ( reviews)

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Book Synopsis Chemical and Functional Genomic Approaches to Stem Cell Biology and Regenerative Medicine by : Sheng Ding

Download or read book Chemical and Functional Genomic Approaches to Stem Cell Biology and Regenerative Medicine written by Sheng Ding. This book was released on 2008-02-08. Available in PDF, EPUB and Kindle. Book excerpt: Scientists believe that stem cells have the potential to revolutionize the treatment of numerous diseases and conditions. This guide covers recent advances in technologies and their applications in stem cell biology, addressing the use of both embryonic and adult stem cells and discussing diverse technologies, including genome-wide expression analysis, informatics, chemical genomics, and more. Applications covered encompass self-renewal, differentiation, reprogramming, and regeneration in model organisms. This is a premier reference for practicing professionals involved in stem cell research and students.

Functional Genomic Approaches Toward the Regenerative Medicine

2003 Chemistry, Organic
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Release : 2003
Genre : Chemistry, Organic
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Functional Genomic Approaches Toward the Regenerative Medicine by : Sheng Ding

Download or read book Functional Genomic Approaches Toward the Regenerative Medicine written by Sheng Ding. This book was released on 2003. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in stem cell and developmental biology have great implications for treating many devastating diseases, such as Parkinson's disease, diabetes, liver failure, and cancer via cell-based therapy and/or by stimulation of tissue regeneration in vivo . However, a number of obstacles must be overcome before we can fully harness their immense therapeutic potentials in mammalian regeneration. This requires a better understanding of the signaling pathways that control cell fate and an improved ability to manipulate stem cell proliferation and differentiation. Therefore we have developed various functional genomic technologies (including combinatorial technologies, genome-wide gene knock-in and knock-out technologies using arrayed cDNA and siRNA libraries, and high throughput phenotypic cell-based screens) to identify small molecules and genes that can permit precise regulation of stem cell fate in a wide variety of systems including pluripotent embryonic stem cells and adult neural stem cells.

Chemical Biology in Regenerative Medicine

2014-06-18 Science
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Release : 2014-06-18
Genre : Science
Kind : eBook
Book Rating : 755/5 ( reviews)

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Book Synopsis Chemical Biology in Regenerative Medicine by : Charles C. Hong

Download or read book Chemical Biology in Regenerative Medicine written by Charles C. Hong. This book was released on 2014-06-18. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Biology in Regenerative Medicine: Bridging Stem Cells and Future Therapies The field of regenerative medicine has advanced at a rapid pace and this comprehensive summary of new developments is a timely contribution to the field as clinical trials have begun to assess the safety and efficacy of cell-based therapies. In Chemical Biology in Regenerative Medicine, an international team of experts provides an overview of progress towards clinical application in the areas of transplantation (allogenic and autologous), manipulation of niche environment and homing, and cell reprogramming (trans-differentiation and de-differentiation). The book highlights the interdisciplinary approaches undertaken to resolve current technical problems in regenerative medicine, with special attention paid to small molecules and biomaterials engineering. This volume provides an essential overview of this emerging technology for researchers in academic, industrial and clinical environments working in regenerative medicine, chemical biology, biochemistry, cell biology, biomaterials and bioengineering. It is appropriate for training students and newcomers to the field, benefitting readers in broadening their knowledge and giving them insights to regenerative chemical biology, as well as encouraging readers to implement the key points in their own fields of study to develop new technologies.

Genomics, Proteomics, and Metabolomics

2019-11-14 Science
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Release : 2019-11-14
Genre : Science
Kind : eBook
Book Rating : 275/5 ( reviews)

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Book Synopsis Genomics, Proteomics, and Metabolomics by : Babak Arjmand

Download or read book Genomics, Proteomics, and Metabolomics written by Babak Arjmand. This book was released on 2019-11-14. Available in PDF, EPUB and Kindle. Book excerpt: This book provides thorough coverage of high-throughput OMICs technologies for the monitoring of stem cells and regenerative medicine. Specific topics covered include the genomics, proteomics, and metabolomics aspects of regenerative medicine, metabolic profiling of mesenchymal stem cells, genome profiling of mesenchymal stem cells, OMICs monitoring of stem cell-derived exosomes, stem cell proteomics, lipidomics, OMICs profiling of cancer (stem) cells, and finally ethical considerations of OMICs-based investigations. Chapters are authored by world-renowned scientists who have valuable expertise in the field of OMICs and regenerative medicine. Genomics, Proteomics, and Metabolomics: Stem Cells Monitoring in Regenerative Medicine, part of Springer’s Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers, clinicians, biologists, biochemists, and pharmaceutical experts conducting research in the fields of stem cell biology, molecular aspects of stem cell research, tissue engineering, regenerative medicine, cellular therapy, OMICs, bioinformatics, and ethics.

Stem Cells & Regenerative Medicine

2010-11-01 Science
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Release : 2010-11-01
Genre : Science
Kind : eBook
Book Rating : 605/5 ( reviews)

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Book Synopsis Stem Cells & Regenerative Medicine by : Krishnarao Appasani

Download or read book Stem Cells & Regenerative Medicine written by Krishnarao Appasani. This book was released on 2010-11-01. Available in PDF, EPUB and Kindle. Book excerpt: Defined as, “The science about the development of an embryo from the fertilization of the ovum to the fetus stage,” embryology has been a mainstay at universities throughout the world for many years. Throughout the last century, embryology became overshadowed by experimental-based genetics and cell biology, transforming the field into developmental biology, which replaced embryology in Biology departments in many universities. Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both embryology and developmental biology to provide an understanding of the molecular portrait of a “development cell.” That new integrated approach is known as stem-cell biology; it is an understanding of the embryology and development together at the molecular level using engineering, imaging and cell culture principles, and it is at the heart of this seminal book. Stem Cells and Regenerative Medicine: From Molecular Embryology to Tissue Engineering is completely devoted to the basic developmental, cellular and molecular biological aspects of stem cells as well as their clinical applications in tissue engineering and regenerative medicine. It focuses on the basic biology of embryonic and cancer cells plus their key involvement in self-renewal, muscle repair, epigenetic processes, and therapeutic applications. In addition, it covers other key relevant topics such as nuclear reprogramming induced pluripotency and stem cell culture techniques using novel biomaterials. A thorough introduction to stem-cell biology, this reference is aimed at graduate students, post-docs, and professors as well as executives and scientists in biotech and pharmaceutical companies.

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