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Applying Genomic and Proteomic Microarray Technology in Drug Discovery

2004-12-28 Medical
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Release : 2004-12-28
Genre : Medical
Kind : eBook
Book Rating : 130/5 ( reviews)

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Book Synopsis Applying Genomic and Proteomic Microarray Technology in Drug Discovery by : Robert S. Matson

Download or read book Applying Genomic and Proteomic Microarray Technology in Drug Discovery written by Robert S. Matson. This book was released on 2004-12-28. Available in PDF, EPUB and Kindle. Book excerpt: Microarrays play an increasingly significant role in drug discovery. Written by a leader in the field, Applying Genomic and Proteomic Microarray Technology in Drug Discovery highlights, describes, and evaluates current scientific research using microarray technology in genomic and proteomic applications. The author addresses the drawbacks, helping

Applying Genomic and Proteomic Microarray Technology in Drug Discovery, Second Edition

2013-03-13 Medical
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Release : 2013-03-13
Genre : Medical
Kind : eBook
Book Rating : 633/5 ( reviews)

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Book Synopsis Applying Genomic and Proteomic Microarray Technology in Drug Discovery, Second Edition by : Robert S. Matson

Download or read book Applying Genomic and Proteomic Microarray Technology in Drug Discovery, Second Edition written by Robert S. Matson. This book was released on 2013-03-13. Available in PDF, EPUB and Kindle. Book excerpt: Microarrays play an increasingly significant role in drug discovery. The commercial landscape has changed dramatically over the past few years and researchers have made great advancements with regard to construction and use. Now in its second edition, Applying Genomic and Proteomic Microarray Technology in Drug Discovery highlights, describes, and evaluates current scientific research using microarray technology in genomic and proteomic applications. Updated and revised to reflect recent progress in the field, the second edition discusses: Expanded omics-driven applications, including the areas of metabolomics and chemical biology The commercialization of the microarray platform, with a historical perspective aimed at recognizing key technological developments Solid-supports (substrates) and surface chemistries currently used in the creation of nucleic acid and protein microarrays Different approaches to producing microarrays that achieve spot equality with the same number of molecules properly oriented The development of the gene expression microarray and representative applications The development of protein microarray technology, including its history and key applications Unique to this edition is a new chapter on multiplex assays that examines the development and applications of arrays across diverse platforms. It discusses applications for qPCR, multiplex lateral flow, and multiplex bead assays. It also presents platform-to-platform comparisons. Microarrays remain an invaluable tool for omics-based research not only in drug discovery, but in the life sciences, in clinical research, and for diagnostic applications worldwide. This volume presents the current state of the art on the utility of this technology to solve a host of important biological problems.

Microarray Innovations

2009-04-02 Medical
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Release : 2009-04-02
Genre : Medical
Kind : eBook
Book Rating : 513/5 ( reviews)

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Book Synopsis Microarray Innovations by : Gary Hardiman

Download or read book Microarray Innovations written by Gary Hardiman. This book was released on 2009-04-02. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, high-density DNA microarrays have revolutionized biomedical research and drug discovery efforts by the pharmaceutical industry. Their efficacy in identifying and prioritizing drug targets based on their ability to confirm a large number of gene expression measurements in parallel has become a key element in drug discovery. Microarr

Protein Microarray Technology

2006-03-06 Science
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Release : 2006-03-06
Genre : Science
Kind : eBook
Book Rating : 215/5 ( reviews)

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Book Synopsis Protein Microarray Technology by : Dev Kambhampati

Download or read book Protein Microarray Technology written by Dev Kambhampati. This book was released on 2006-03-06. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first of its kind in the field of protein microarrays and addresses novel strategies for constructing highly functional and biocompatible microarrays for screening proteins. The list of authors consisting of world leading experts provide a roadmap for solving the complex challenges that are currently faced while monitoring protein-protein interactions over a wide range of microarray platforms. In doing so, they also offer a comprehensive overview of microarray surface chemistry, detection technologies, fabrication options for array development, and data analysis of numerous types of protein interactions. Topics covered include: -Types of biomolecular interactions -Surface chemistry -Detection technologies -Spotting technologies -Bioinformatics/data analysis. While primarily intended to serve as a reference for researchers and students embarking on the exciting fields of proteomics, drug discovery and clinical diagnostics, this technology is also expected to potentially impact the areas of food diagnostics, environmental monitoring and national security.

Predictive Approaches in Drug Discovery and Development

2012-02-14 Medical
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Release : 2012-02-14
Genre : Medical
Kind : eBook
Book Rating : 264/5 ( reviews)

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Book Synopsis Predictive Approaches in Drug Discovery and Development by : J. Andrew Williams

Download or read book Predictive Approaches in Drug Discovery and Development written by J. Andrew Williams. This book was released on 2012-02-14. Available in PDF, EPUB and Kindle. Book excerpt: Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development and contains state-of-the-art appraisals on the practical utility of genomic, biochemical, and protein biomarkers. Case histories and lessons from successful and unsuccessful applications of biomarkers are included along with key chapters on GLP validation, safety biomarkers and proteomics biomarkers. Regulatory agency perspectives and initiatives both in the US and internationally are also discussed.

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