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Applications in High Resolution Mass Spectrometry

2017-03-07 Science
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Release : 2017-03-07
Genre : Science
Kind : eBook
Book Rating : 489/5 ( reviews)

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Book Synopsis Applications in High Resolution Mass Spectrometry by : Roberto Romero-González

Download or read book Applications in High Resolution Mass Spectrometry written by Roberto Romero-González. This book was released on 2017-03-07. Available in PDF, EPUB and Kindle. Book excerpt: Applications of High Resolution Mass Spectrometry: Food Safety and Pesticide Residue Analysis is the first book to offer complete coverage of all aspects of high resolution mass spectrometry (HRMS) used for the analysis of pesticide residue in food. Aimed at researchers and graduate students in food safety, toxicology, and analytical chemistry, the book equips readers with foundational knowledge of HRMS, including established and state-of-the-art principles and analysis strategies. Additionally, it provides a roadmap for implementation, including discussions of the latest instrumentation and software available. Detailed coverage is given to the application of HRMS coupled to ultra high-performance liquid chromatography (UHPLC-HRMS) in the analysis of pesticide residue in fruits and vegetables and food from animal origin. The book also discusses extraction procedures and the challenges of sample preparation, gas chromatography coupled to high resolution mass spectrometry, flow injection-HRMS, ambient ionization, and identification of pesticide transformation products in food. Responding to the fast development and application of these new procedures, this book is an essential resource in the food safety field. Arms researchers with an in-depth resource devoted to the rapid advances in HRMS tools and strategies for pesticide residue analysis in food Provides a complete overview of analytical methodologies and applications of HRMS, including UHPLC-HRMS, HRMS coupled with time of flight (TOF) and/or GC-Orbitrap, and flow injection-HRMS Discusses the current international regulations and legislation related to the use of HRMS in pesticide residue analysis Features a chapter on the hardware and software available for HRMS implementation Offers separate chapters on HRMS applied to pesticide residue analysis in fruits and vegetables and in food from animal origin

High-Resolution Mass Spectrometry and Its Diverse Applications

2022-10 Science
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Release : 2022-10
Genre : Science
Kind : eBook
Book Rating : 258/5 ( reviews)

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Book Synopsis High-Resolution Mass Spectrometry and Its Diverse Applications by : Sreeraj Gopi

Download or read book High-Resolution Mass Spectrometry and Its Diverse Applications written by Sreeraj Gopi. This book was released on 2022-10. Available in PDF, EPUB and Kindle. Book excerpt: "This informative book offers a wide range of knowledge on the technologies and applications of the cutting-edge field of high-resolution mass spectrometry (HRMS) in different areas of analysis. HRMS has changed the nature of experimentation and investigation in so many analytical realms. Determining exact mass determination, high resolution, and specificity-via the special features provided by HRMS instruments-is now possible for determining the composition of the analyte of interest, both qualitatively and quantitatively. High-Resolution Mass Spectrometry and Its Diverse Applications: Cutting-Edge Techniques and Instrumentation begins with an overview of the basic instrumentation techniques and goes on to present research on diverse new uses of HRMS in clinical testing, such as for therapeutic drug designing, discovery, and development; in forensic studies and investigations; in quality management systems; for analysis of pesticides; for analysis of single cells; in analysis of fossil fuels; for use in space and planetary science; and more. Chapters relay how HRMS plays an important role in the structure elucidation and unknown determination in many fields and is a great measure to be used for quantitative analyses. The book considers how these properties make the technique a strong aid in many areas. This volume highlights how HRMS can be a useful tool for scientists and researchers, faculty and students, and industry professionals in many scientific areas of study"--

Applications of high-resolution mass spectrometry in drug discovery and development

2014
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Release : 2014
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Kind : eBook
Book Rating : 562/5 ( reviews)

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Book Synopsis Applications of high-resolution mass spectrometry in drug discovery and development by :

Download or read book Applications of high-resolution mass spectrometry in drug discovery and development written by . This book was released on 2014. Available in PDF, EPUB and Kindle. Book excerpt:

Time-of-flight Mass Spectrometry and Its Applications

1994 Science
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Release : 1994
Genre : Science
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Book Synopsis Time-of-flight Mass Spectrometry and Its Applications by : Edward William Schlag

Download or read book Time-of-flight Mass Spectrometry and Its Applications written by Edward William Schlag. This book was released on 1994. Available in PDF, EPUB and Kindle. Book excerpt: The resurgence of time-of-flight mass spectrometry (TOF-MS) has had its origin in the simplicity of construction and application of such instruments together with the high transmission and the great increase in resolution that has been achieved. The instrument lends itself naturally to a coupling with pulsed laser sources, though this is not a prerequisite. It also affords a time resolution far beyond that traditionally achieved with mass spectrometric rapid scan techniques - a recent example being the real-time analysis of a multi-component mixture from an automobile exhaust. Furthermore, the mass range appears to be extremely large: mass up to 500 kDa and beyond what is being readily measured in the laboratory today.The present set of contributions attempts to give a survey of current applications from many of the active groups in the field. A variety of new applications are considered which are no doubt just the beginning of large new areas of application. By presenting this work in book form it is hoped that it will be of help to the many groups intending to initiate work in this rapidly expanding new area of mass spectrometry.

High-Resolution Mass Spectroscopy for Phytochemical Analysis

2021-09-30 Science
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Release : 2021-09-30
Genre : Science
Kind : eBook
Book Rating : 613/5 ( reviews)

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Book Synopsis High-Resolution Mass Spectroscopy for Phytochemical Analysis by : Sreeraj Gopi

Download or read book High-Resolution Mass Spectroscopy for Phytochemical Analysis written by Sreeraj Gopi. This book was released on 2021-09-30. Available in PDF, EPUB and Kindle. Book excerpt: This new volume provides a bird’s-eye view of the properties, utilization, and importance of high resolution mass spectrometry (HRMS) for phytochemical analysis. The book discusses the new and state-of-the-art technologies related to HRMS in phytochemical analysis for the food industry in a comprehensive manner. Phytochemical characterization of plants is important in the food and nutraceutical industries and is also necessary in the procedures followed for drug development, toxicology determination, forensic studies, origin verification, quality assurance, etc. Easy determination of active compounds and isolation as well as purification of the same from natural matrices are required, and the possibilities and advantages of HRMS pave the way for improved analysis patterns in phytochemistry. This book is unique in that its sole consideration is on the importance of HRMS in the field of phytochemical analysis. Along with an overview of basic instrumental information, the volume provides a detailed account of data processing and dereplication strategies. Technologies such as bioanalytical techniques and bioassays are considered also to provide support for the functions of the instruments used. In addition, a case study is presented to depict the complete phytochemical characterization of a matrix by HRMS. The book covers processing and computational techniques, dereplication, hyphenation, high-resolution bioassays, bioanalytical screening/purification techniques, applications of gas chromatography–high-resolution mass spectrometry, and more. Key features: Covers the fundamental instrumentation and techniques Discusses HRMS-based phytochemical research details Focuses strictly on the phytochemical considerations High-Resolution Mass Spectroscopy for Phytochemical Analysis: State-of-the-Art Applications and Techniques will be a valuable reference guide and resource for researchers, faculty and students in related fields, as well as those in the phytochemical industries.

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