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A Personalized Algorithm to Control Blood Glucose Levels During Exercise in Individuals with Type 1 Diabetes

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Author :
Release : 2022
Genre :
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis A Personalized Algorithm to Control Blood Glucose Levels During Exercise in Individuals with Type 1 Diabetes by : Milad Ghanbari

Download or read book A Personalized Algorithm to Control Blood Glucose Levels During Exercise in Individuals with Type 1 Diabetes written by Milad Ghanbari. This book was released on 2022. Available in PDF, EPUB and Kindle. Book excerpt: "Exercise has numerous well-established benefits, such as decreased risk of cardiovascular disease, improved lipid profile, and overall improved well being. These benefits are especially important to patients with type 1 diabetes, given the increased risk of cardiovascular disease in this population. Despite the established benefits of exercise, moderate intensity aerobic exercise increases the risk of hypoglycemia in individuals with type 1 diabetes, making exercise more difficult in this population. For exercise management in type 1 diabetes, carbohydrate ingestion and insulin reduction are recommended to prevent hypoglycemia. However, due to the large inter-individual variability in glucose responses to exercise, these general recommendations are not always efficient in preventing hypoglycemia. In the present thesis, a personalized closed-loop algorithm based on each patient's glucose response to exercise was developed to reduce the risk of exercise-induced hypoglycemia. The designed algorithm is based on a prediction mathematical model and uses an optimization-based method. After each exercise session, the prediction model is updated by estimating the exercise effect using a least squares algorithm. Given the updated model, an optimization problem is formulated to obtain recommendations of basal rate reduction and carbohydrate intake for the upcoming exercise session. The developed algorithm was evaluated on 100 virtual patients in a computer simulation environment. The results showed that there was a significant reduction in hypoglycemia with the developed algorithm in comparison to the conventional exercise management strategy, without significant increase in time in hyperglycemia. Furthermore, it was shown that when exercise is announced earlier, the algorithm performs better and leads to lower risk of hypoglycemia. The developed algorithm has the potential to facilitate physical activity in type 1 diabetes and thus improve quality of life. Clinical studies to assess the algorithm are warranted"--

Personalized Predictive Modeling in Type 1 Diabetes

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Release : 2017-12-11
Genre : Computers
Kind : eBook
Book Rating : 469/5 ( reviews)

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Book Synopsis Personalized Predictive Modeling in Type 1 Diabetes by : Eleni I. Georga

Download or read book Personalized Predictive Modeling in Type 1 Diabetes written by Eleni I. Georga. This book was released on 2017-12-11. Available in PDF, EPUB and Kindle. Book excerpt: Personalized Predictive Modeling in Diabetes features state-of-the-art methodologies and algorithmic approaches which have been applied to predictive modeling of glucose concentration, ranging from simple autoregressive models of the CGM time series to multivariate nonlinear regression techniques of machine learning. Developments in the field have been analyzed with respect to: (i) feature set (univariate or multivariate), (ii) regression technique (linear or non-linear), (iii) learning mechanism (batch or sequential), (iv) development and testing procedure and (v) scaling properties. In addition, simulation models of meal-derived glucose absorption and insulin dynamics and kinetics are covered, as an integral part of glucose predictive models. This book will help engineers and clinicians to: select a regression technique which can capture both linear and non-linear dynamics in glucose metabolism in diabetes, and which exhibits good generalization performance under stationary and non-stationary conditions; ensure the scalability of the optimization algorithm (learning mechanism) with respect to the size of the dataset, provided that multiple days of patient monitoring are needed to obtain a reliable predictive model; select a features set which efficiently represents both spatial and temporal dependencies between the input variables and the glucose concentration; select simulation models of subcutaneous insulin absorption and meal absorption; identify an appropriate validation procedure, and identify realistic performance measures. Describes fundamentals of modeling techniques as applied to glucose control Covers model selection process and model validation Offers computer code on a companion website to show implementation of models and algorithms Features the latest developments in the field of diabetes predictive modeling

Type 1 Diabetes

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Release : 2012-03-17
Genre : Biography & Autobiography
Kind : eBook
Book Rating : 538/5 ( reviews)

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Book Synopsis Type 1 Diabetes by : Ian Gallen

Download or read book Type 1 Diabetes written by Ian Gallen. This book was released on 2012-03-17. Available in PDF, EPUB and Kindle. Book excerpt: There has been a recent surge of new data on the subject of exercise and sport in type I diabetes, as well as great interest from the multidisciplinary healthcare teams looking after such patients. Providing advice and support to enable athletes to manage their diabetes during and after sport is an essential part of diabetes care. Type I Diabetes: Clinical Management of the Athlete outlines best practice and scientific progress in the management of people with type I diabetes who undertake a sport at any level. The book explores endocrine response to exercise, hypoglycemia and dietetics in the diabetic patient, and provides real-life examples of type I diabetes management at the professional athlete level. It is the first source of reference for specialists in diabetes when seeking advice on how to manage their patient and provides practical advice for equipping the type I diabetes patient with the ability to fulfill their sporting potential.

Exercise and Diabetes

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Release : 2013-05-30
Genre : Medical
Kind : eBook
Book Rating : 07X/5 ( reviews)

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Book Synopsis Exercise and Diabetes by : Sheri R. Colberg

Download or read book Exercise and Diabetes written by Sheri R. Colberg. This book was released on 2013-05-30. Available in PDF, EPUB and Kindle. Book excerpt: Physical movement has a positive effect on physical fitness, morbidity, and mortality in individuals with diabetes. Although exercise has long been considered a cornerstone of diabetes management, many health care providers fail to prescribe it. In addition, many fitness professionals may be unaware of the complexities of including physical activity in the management of diabetes. Giving patients or clients a full exercise prescription that take other chronic conditions commonly accompanying diabetes into account may be too time-consuming for or beyond the expertise of many health care and fitness professionals. The purpose of this book is to cover the recommended types and quantities of physical activities that can and should be undertaken by all individuals with any type of diabetes, along with precautions related to medication use and diabetes-related health complications. Medications used to control diabetes should augment lifestyle improvements like increased daily physical activity rather than replace them. Up until now, professional books with exercise information and prescriptions were not timely or interactive enough to easily provide busy professionals with access to the latest recommendations for each unique patient. However, simply instructing patients to “exercise more” is frequently not motivating or informative enough to get them regularly or safely active. This book is changing all that with its up-to-date and easy-to-prescribe exercise and physical activity recommendations and relevant case studies. Read and learn to quickly prescribe effective and appropriate exercise to everyone.

Physical Activity and Type 1 Diabetes

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Release : 2020-01-17
Genre :
Kind : eBook
Book Rating : 23X/5 ( reviews)

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Book Synopsis Physical Activity and Type 1 Diabetes by : Johan Henrik Jendle

Download or read book Physical Activity and Type 1 Diabetes written by Johan Henrik Jendle. This book was released on 2020-01-17. Available in PDF, EPUB and Kindle. Book excerpt:

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