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Venoms to Drugs

2015-02-11 Science
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Release : 2015-02-11
Genre : Science
Kind : eBook
Book Rating : 634/5 ( reviews)

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Book Synopsis Venoms to Drugs by : Glenn King

Download or read book Venoms to Drugs written by Glenn King. This book was released on 2015-02-11. Available in PDF, EPUB and Kindle. Book excerpt: This unique book will provide an up to date and comprehensive account of the potential of peptides and proteins from animal venoms as possible therapeutics. The pharmaceutical industry has become increasingly interested in biologics from animal venoms as a potential source for therapeutic agents in recent years, with a particularly emphasis on peptides. To date six drugs derived from venom peptides or proteins have been approved by the FDA, with nine further agents currently being investigated in clinical trials. In addition to these drugs in approved or advanced stages of development, many more peptides and proteins are being studied in varying stages of preclinical development. Topics covered include chemistry and structural biology of animal venoms, proteomic and transcriptomic approaches to drug discovery, bioassays, high-throughput screens and target identification, and reptile, scorpion, spider and cone snail venoms as a platform for drug development. Case studies are used to illustrate methods and successes and highlight issues surrounding administration and other important lessons that have been learnt from the development of approved therapeutics based on venoms. The first text to focus on this fascinating area and bridging an important gap, this book will provide the reader with essential and current knowledge on this fast-developing area. Venoms to Drugs will find wide readership with researchers working in academia and industry working in all medicinal and pharmaceutical areas.

Venoms to Drugs

2015-01-27 Science
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Release : 2015-01-27
Genre : Science
Kind : eBook
Book Rating : 878/5 ( reviews)

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Book Synopsis Venoms to Drugs by : Glenn F. King

Download or read book Venoms to Drugs written by Glenn F. King. This book was released on 2015-01-27. Available in PDF, EPUB and Kindle. Book excerpt: The pharmaceutical industry has become increasingly interested in biologics from animal venoms as a potential source for therapeutic agents in recent years, with a particularly emphasis on peptides. To date six drugs derived from venom peptides or proteins have been approved by the FDA, with nine further agents currently being investigated in clinical trials. In addition to these drugs in approved or advanced stages of development, many more peptides and proteins are being studied in varying stages of preclinical development. This unique book provides an up to date and comprehensive account of the potential of peptides and proteins from animal venoms as possible therapeutics. Topics covered include chemistry and structural biology of animal venoms, proteomic and transcriptomic approaches to drug discovery, bioassays, high-throughput screens and target identification, and reptile, scorpion, spider and cone snail venoms as a platform for drug development. Case studies are used to illustrate methods and successes and highlight issues surrounding administration and other important lessons that have been learnt from the development of approved therapeutics based on venoms. The first text to focus on this fascinating area and bridging an important gap, this book provides the reader with essential and current knowledge on this fast-developing area. Venoms to Drugs will find wide readership with researchers working in academia and industry working in all medicinal and pharmaceutical areas.

Venom and Toxin as Targeted Therapy

2019-10-01 Science
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Release : 2019-10-01
Genre : Science
Kind : eBook
Book Rating : 897/5 ( reviews)

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Book Synopsis Venom and Toxin as Targeted Therapy by : Hang Fai (Henry) Kwok

Download or read book Venom and Toxin as Targeted Therapy written by Hang Fai (Henry) Kwok. This book was released on 2019-10-01. Available in PDF, EPUB and Kindle. Book excerpt: Targeted therapy has developed significantly in the last one and half decades, prescribing specific medications for treatment of particular diseases, such as cancer, diabetes, and heart disease. One of the most exciting recent developments in targeted therapies was the isolation of disease-specific molecules from natural resources, such as animal venoms and plant metabolites/toxins, for use as templates for new drug motif designs. In addition, the study of venom proteins/peptides and toxins naturally targeted mammalian receptors and demonstrated high specificity and selectivity towards defined ion channels of cell membranes. Research has also focsed intensely on receptors. The focus of this Special Issue of Toxins addressed the most recent advances using animal venoms, such as frog secretions, bee/ant venoms and plant/fungi toxins, as medicinal therapy. Recent advances in venom/toxin/immunotoxins for targeted cancer therapy and immunotherapy, along with using novel disease-specific venom-based protein/peptide/toxin and currently available FDA-approved drugs for combinationtreatments will be discussed. Finally, we included an overview of select promising toad/snake venom-based peptides/toxins potentially able to address the forthcoming challenges in this field. Both research and review articles proposing novelties or overviews, respectively, were published in this Special Issue after rigorous evaluation and revision by expert peer reviewers.

Drugs and Poisons in Humans

2006-01-16 Medical
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Release : 2006-01-16
Genre : Medical
Kind : eBook
Book Rating : 797/5 ( reviews)

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Book Synopsis Drugs and Poisons in Humans by : Osamu Suzuki

Download or read book Drugs and Poisons in Humans written by Osamu Suzuki. This book was released on 2006-01-16. Available in PDF, EPUB and Kindle. Book excerpt: Unique analysis of drugs and poisons to facilitate testing in all laboratories even by inexperienced chemists Includes source of chemicals needed for the experiments Texts are composed by 67 experts in analyzing the respective compounds Clear and uniform structure of chapters for ease of reading The text is illustrated by many diagrams and tables

Venoms, Toxins and Drugs

1990 Toxins
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Author :
Release : 1990
Genre : Toxins
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Venoms, Toxins and Drugs by : Alan L. Harvey

Download or read book Venoms, Toxins and Drugs written by Alan L. Harvey. This book was released on 1990. Available in PDF, EPUB and Kindle. Book excerpt:

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