1# Library to Find Best eBook for Read
Author : Tuan Leng Tay
Release : 2022-05-03
Genre : Medical
Kind : eBook
Book Rating : 707/5 ( reviews)
Book Synopsis Understanding the Roles of Glia and Circulating Leukocytes in Neurodegenerative Diseases by : Tuan Leng Tay
Download or read book Understanding the Roles of Glia and Circulating Leukocytes in Neurodegenerative Diseases written by Tuan Leng Tay. This book was released on 2022-05-03. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Tania Spohr
Release : 2020-05-20
Genre : Science
Kind : eBook
Book Rating : 536/5 ( reviews)
Book Synopsis Glia in Health and Disease by : Tania Spohr
Download or read book Glia in Health and Disease written by Tania Spohr. This book was released on 2020-05-20. Available in PDF, EPUB and Kindle. Book excerpt: The book will highlight the role played by glial cells in the central and peripheral nervous systems in both healthy and unhealthy individuals. Among all processes involved, we will discuss the importance of the enteric nervous system in the control of gut homeostasis, in the interaction with the immune system, and its participation in pathological conditions such as metabolic syndrome. We will also look at the relevance of astrocytes during synaptic transmission and the regulation of plasticity by releasing gliotransmitters. Ultimately, we will highlight the influence of astrocytes during the development of a number of neurodegenerative diseases, such as multiple sclerosis and Alzheimer’s disease, focusing on how the serum levels of the astrocytic protein S100B can be used as a biomarker for clinical decisions.
Author : Ishan Patro
Release : 2022-04-09
Genre : Medical
Kind : eBook
Book Rating : 131/5 ( reviews)
Book Synopsis The Biology of Glial Cells: Recent Advances by : Ishan Patro
Download or read book The Biology of Glial Cells: Recent Advances written by Ishan Patro. This book was released on 2022-04-09. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the role of glial cells (astrocytes, microglia, oligodendroglia, satellite cells, and Schwann cells) in neuronal health and diseases. It discusses the latest advances in understanding their origin, differentiation, and hemostasis. The book also examines the role of microglial cells in central nervous system (CNS) development, maintenance, and synaptic plasticity. Further, the book presents the functions of astrocytes in healthy CNS and their critical role in CNS disorders, including Parkinson's and Alzheimer's diseases. Notably, the book describes the pathobiology, molecular pathogenesis, stem cells, and imaging characteristics of gliomas. It defines the role of glial cells in regulating iron homeostasis and their effect on the neurodegeneration of neurons. Lastly, it covers the structure, function, and pathology of oligodendrocytes and their role in neuronal health and disease.
Author : El-Mansoury, Bilal
Release : 2023-12-18
Genre : Science
Kind : eBook
Book Rating : 763/5 ( reviews)
Book Synopsis Physiology and Function of Glial Cells in Health and Disease by : El-Mansoury, Bilal
Download or read book Physiology and Function of Glial Cells in Health and Disease written by El-Mansoury, Bilal. This book was released on 2023-12-18. Available in PDF, EPUB and Kindle. Book excerpt: Glial cells, including microglia, astrocytes, oligodendrocytes, and their progenitors NG2-glia, serve as key players in maintaining structural integrity and complex brain homeostasis. They actively participate in neurotransmission, energy metabolism, synaptic plasticity, neurogenesis, ion balance, immune defense, and the clearance of neuronal debris. However, the physiological functions of glial cells are often compromised in aging, neurodegenerative diseases such as Alzheimer's, Parkinson's, ALS, and multiple sclerosis, as well as in gliomas, brain tumors demanding specialized understanding for effective therapeutic interventions. Physiology and Function of Glial Cells in Health and Disease provides a comprehensive exploration of the vital role played by glial cells in maintaining neural homeostasis within the central nervous system (CNS). This book delves into the intricate interaction between glial cells and neurons, shedding light on their essential contributions to neural function and overall brain health. The book also highlights emerging research on astrocyte reprogramming for the management of neurodegenerative diseases, offering a glimpse into potential future therapies. This book is an essential resource for researchers, clinicians, and students in the field of neuroscience. Its academic tone, coupled with in-depth discussions and cutting-edge insights, makes it a valuable reference for anyone seeking a comprehensive understanding of the role of glial cells in both health and disease.
Author : Carlos Barcia
Release : 2016-05-30
Genre : Neurosciences. Biological psychiatry. Neuropsychiatry
Kind : eBook
Book Rating : 359/5 ( reviews)
Book Synopsis Glial Cells: Managers of Neuro-immunity by : Carlos Barcia
Download or read book Glial Cells: Managers of Neuro-immunity written by Carlos Barcia. This book was released on 2016-05-30. Available in PDF, EPUB and Kindle. Book excerpt: Immune responses within the brain are still scarcely explored. Nerve tissue damage is accompanied by the activation of glial cells, primarily microglia and astroglia, and such activation is responsible for the release of cytokines and chemokines that maintain the local inflammatory response and actively recruit lymphocytes and monocytes to the damaged areas. Theoretically, these responses are designed to repair the brain damage. However, alterations, or a chronic perpetuation of these responses may underlie a number of neuro-pathologies. It is thought that each inflammatory scenario within the brain have a specific biochemical footprint characterized by the release of determined cytokines, chemokines and growing factors able to define particular immunological responses. Alongside, glial cells transform their cell body, become larger and develop higher number of branches adopting an active morphological phenotype. These changes are related with the search of interactions with other cells, such as bystander resident cells of the brain parenchyma, but also cells homing from the blood stream. In this process, microglia and astrocytes communicates with other cells by the formation of specific intercellular connections that are still poorly understood. These interactions are complex and entail the arrangement of cytoskeletal compounds, secretory and phagocytic domains. In this particular crosstalk there is a two-way communication in which glial cells and target cells come together establishing interfaces with specific information exchange. This way, glial cells orchestrate the particular response recruiting cellular subsets within the central nervous system and organizing the resolution of the brain damage. In this Frontiers Research Topic, we compile a selection of articles unfolding diverse aspects of glial-derived inflammation, focused on neurodegenerative diseases and other nervous system disorders, with special emphasis on microglia/macrophages as leading actors managing neuro-immunity.
