1# Library to Find Best eBook for Read
Author : Peter Vaupel
Release : 1995
Genre : Medical
Kind : eBook
Book Rating : /5 ( reviews)
Book Synopsis Tumor Oxygenation by : Peter Vaupel
Download or read book Tumor Oxygenation written by Peter Vaupel. This book was released on 1995. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Giovanni Melillo
Release : 2013-11-09
Genre : Medical
Kind : eBook
Book Rating : 673/5 ( reviews)
Book Synopsis Hypoxia and Cancer by : Giovanni Melillo
Download or read book Hypoxia and Cancer written by Giovanni Melillo. This book was released on 2013-11-09. Available in PDF, EPUB and Kindle. Book excerpt: The imbalance between rapidly proliferating tumor cells and inadequate and inefficient tumor vasculature leads to a decrease in oxygen levels (hypoxia and/or anoxia) in tumor tissues. Intra-tumor hypoxia profoundly affects the biological behavior of cancer cells, which become resistant to conventional therapies and acquire a more invasive and metastatic phenotype. Hypoxia is a hallmark of the malignant phenotype and a key feature of the tumor microenvironment. Hypoxia Inducible Factor 1 (HIF-1) is a master regulator of the transcriptional response to oxygen deprivation. HIF triggers the expression of genes whose products induce angiogenesis, decrease oxygen consumption, switch metabolism to glycolysis, maintain a stem cell phenotype and select for more invasive and metastatic cells. Therapeutic approaches targeting HIF, directly or downstream mediators of its transcriptional activity, are being developed. Intra-tumor hypoxia is a topic has been gaining scientific interest over the last few years for its wide involvement in many physiological and pathological processes. This volume will cover the latest research and translational aspects associated with intra-tumor hypoxia, along with opportunities for drug development offered by this unique feature of the tumor microenvironment. The ongoing efforts to translate our understanding of the biology underlying intra-tumor hypoxia in viable therapeutic options face many challenges, but this book will provide an opportunity for an in-depth analysis of the fundamental mechanisms implicated in the adaption to low oxygen levels and will scrutinize the potential for opportunities that are being pursued in both research and the drug development industry.
Author : Christopher J. Gulledge
Release : 1996
Genre : Tumors
Kind : eBook
Book Rating : /5 ( reviews)
Book Synopsis Importance of Supply and Demand in Tumor Oxygenation by : Christopher J. Gulledge
Download or read book Importance of Supply and Demand in Tumor Oxygenation written by Christopher J. Gulledge. This book was released on 1996. Available in PDF, EPUB and Kindle. Book excerpt:
Author : David F. Wilson
Release : 2012-12-06
Genre : Science
Kind : eBook
Book Rating : 055/5 ( reviews)
Book Synopsis Oxygen Transport To Tissue XXIII by : David F. Wilson
Download or read book Oxygen Transport To Tissue XXIII written by David F. Wilson. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: The ISOTT 2001 local organizing committee was pleased to welcome over 140 delegates from around the world to the 29th annual general meeting of the International Society for Oxygen Transport to Tissue. The meeting was held in historic Philadelphia, USA, on the campus of the University of Pennsylvania from August 11 to 15, 2001. In the tradition of ISOTT, the conference was a total immersion experience. Attendees were encouraged to eat together and spend their evenings relaxing together in a style that maximized exchange of ideas and interactions of younger scientists with their more senior colleagues. Delegates participated in a total of 122 presentations including poster displays, selected oral presentations, seminars by invited speakers and a round table discussion. In choosing invited speakers and oral presenters, special emphasis was placed on methods for oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. All of the manuscripts contained in this volume underwent both an editorial and scientific review, and only those meeting both criteria have been published. However, while all efforts have been made to eliminate editorial errors, some have undoubtedly been overlooked, for which the editors apologize.
Author : Paul Okunieff
Release : 2006-06-18
Genre : Science
Kind : eBook
Book Rating : 067/5 ( reviews)
Book Synopsis Oxygen Transport to Tissue XXVI by : Paul Okunieff
Download or read book Oxygen Transport to Tissue XXVI written by Paul Okunieff. This book was released on 2006-06-18. Available in PDF, EPUB and Kindle. Book excerpt: The International Society of Oxygen Transport to Tissue (ISOTT) was founded in 1973 to provide a forum for bioengineers, basic scientists, physiologists, and physicians to discuss new data, original theories, new interpretations of old data, and new technologies for the measurement of oxygen. At each annual meeting all posters are presented orally along with plenary lectures, and all presentations are given in a general session attended by everyone. Each meeting has had a specific focus, ranging from neonatology to physical chemistry to cancer biology. The Society has helped to build many careers, through opportunities to meet leaders in the field, and through awards made to young physicians and scientists. The Society also, through cross fertilization of ideas and scientific comradery, has inspired many breakthroughs in clinical medicine that now benefit mankind. I find myself president of the society after having been a winner of the Melvin Knisely Award for young scientists, in 1991. The 2003 meeting emphasized the role of oxygen and oxygen measurement in tumor growth, metastasis, physiology, and treatment resistance. Additionally, however, completely novel approaches to measurement of tissue oxygen were presented (notably work by Dr. Takahashi) and molecular methods for estimating tissue oxygen were evaluated. Papers discussing other aspects of oxygen measurement and pathophysiology were presented including in vivo ESR spectroscopy (notably including Dr. Swartz and colleagues), exercise physiology, organ transplant outcome (discussed by Dr. Cicco, our 2004 president), circulatory physiology, and cerebral oxygenation (notably including Dr. Chance).
