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Tumor Cell Metabolism and Autophagy as Therapeutic Targets

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Release : 2021-02-24
Genre : Medical
Kind : eBook
Book Rating : 003/5 ( reviews)

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Book Synopsis Tumor Cell Metabolism and Autophagy as Therapeutic Targets by : Carlos Pérez-Plasencia

Download or read book Tumor Cell Metabolism and Autophagy as Therapeutic Targets written by Carlos Pérez-Plasencia. This book was released on 2021-02-24. Available in PDF, EPUB and Kindle. Book excerpt:

Autophagy and Metabolism

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Release : 2022-08-06
Genre : Science
Kind : eBook
Book Rating : 45X/5 ( reviews)

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Book Synopsis Autophagy and Metabolism by : Dhruv Kumar

Download or read book Autophagy and Metabolism written by Dhruv Kumar. This book was released on 2022-08-06. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy and Metabolism: Potential Target for Cancer Therapy presents updates on autophagy in cancer metabolism and how it can be used to develop new, more efficient treatments. Written by experts in the field, the book presents recent research and explains how to translate it to the clinical setting. Sections discuss tumor cell metabolism and autophagy as therapeutic targets, autophagy regulation in cancer, signaling pathways in metabolic dysregulation in solid tumors, metabolic stress and cell death pathways, and the role of the tumor microenvironment. In addition, topics cover combined targeting autophagy, metabolism for cancer therapy, and the autophagy effect on immune cell metabolism. This will be a valuable resource for researchers, oncologists, graduate students, and members of the biomedical field who are interested in learning more about the interaction between autophagy and cancer metabolism. Presents valuable and updated information on the mechanisms of autophagy in cancer metabolism Discusses the various metabolic pathways linked with autophagy that can be a major target for chemotherapeutic strategies Explains how autophagy supports tumor growth by activating metabolic phenotypes in cancer cells and the therapeutic interventions available to halt the process

Cancer Cell Metabolism: A Potential Target for Cancer Therapy

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Release : 2020-02-13
Genre : Medical
Kind : eBook
Book Rating : 919/5 ( reviews)

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Book Synopsis Cancer Cell Metabolism: A Potential Target for Cancer Therapy by : Dhruv Kumar

Download or read book Cancer Cell Metabolism: A Potential Target for Cancer Therapy written by Dhruv Kumar. This book was released on 2020-02-13. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates various aspects of cancer cell metabolism, including metabolic regulation in solid tumours vs. non-solid tumours, the molecular pathways involved in its metabolism, and the role of the tumour microenvironment in the regulation of cancer cell metabolism. It summarizes the complexity of cancer cell metabolism in terms of the switch from anaerobic to aerobic glycolysis and how mitochondrial damage promotes aerobic glycolysis in cancer cells. The respective chapters provide the latest information on the metabolic remodelling of cancer cells and elucidate the important role of the signalling pathways in reprogramming of cancer cell metabolism. In addition, the book highlights the role of autophagy in cancer cell metabolism, and how metabolic crosstalk between cancer cells and cancer-associated fibroblasts promotes cancer cell progression. In closing, it summarizes recent advancements in drug development through targeting cancer metabolism.

Cancer Cell Metabolism

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Author :
Release : 2020
Genre : Cancer cells
Kind : eBook
Book Rating : 925/5 ( reviews)

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Book Synopsis Cancer Cell Metabolism by :

Download or read book Cancer Cell Metabolism written by . This book was released on 2020. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates various aspects of cancer cell metabolism, including metabolic regulation in solid tumours vs. non-solid tumours, the molecular pathways involved in its metabolism, and the role of the tumour microenvironment in the regulation of cancer cell metabolism. It summarizes the complexity of cancer cell metabolism in terms of the switch from anaerobic to aerobic glycolysis and how mitochondrial damage promotes aerobic glycolysis in cancer cells. The respective chapters provide the latest information on the metabolic remodelling of cancer cells and elucidate the important role of the signalling pathways in reprogramming of cancer cell metabolism. In addition, the book highlights the role of autophagy in cancer cell metabolism, and how metabolic crosstalk between cancer cells and cancer-associated fibroblasts promotes cancer cell progression. In closing, it summarizes recent advancements in drug development through targeting cancer metabolism.

Autophagy and Cancer

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Author :
Release : 2013-03-30
Genre : Medical
Kind : eBook
Book Rating : 613/5 ( reviews)

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Book Synopsis Autophagy and Cancer by : Hong-Gang Wang

Download or read book Autophagy and Cancer written by Hong-Gang Wang. This book was released on 2013-03-30. Available in PDF, EPUB and Kindle. Book excerpt: With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about autophagy regulation into better understanding of its role in cancer. This book will cover the latest advances in this area from the basics, such as the molecular machinery for autophagy induction and regulation, up to the current areas of interest such as modulation of autophagy and drug discovery for cancer prevention and treatment. The text will include an explanation on how autophagy can function in both oncogenesis and tumor suppression and a description of its function in tumor development and tumor suppression through its roles in cell survival, cell death, cell growth as well as its influences on inflammation, immunity, DNA damage, oxidative stress, tumor microenvironment, etc. The remaining chapters will cover topics on autophagy and cancer therapy. These pages will serve as a description on how the pro-survival function of autophagy may help cancer cells resist chemotherapy and radiation treatment as well as how the pro-death functions of autophagy may enhance cell death in response to cancer therapy, and how to target autophagy for cancer prevention and therapy − what to target and how to target it. ​

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