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Transcriptional Corepressors: Mediators of Eukaryotic Gene Repression

2013-03-09 Medical
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Release : 2013-03-09
Genre : Medical
Kind : eBook
Book Rating : 950/5 ( reviews)

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Book Synopsis Transcriptional Corepressors: Mediators of Eukaryotic Gene Repression by : Martin L. Privalsky

Download or read book Transcriptional Corepressors: Mediators of Eukaryotic Gene Repression written by Martin L. Privalsky. This book was released on 2013-03-09. Available in PDF, EPUB and Kindle. Book excerpt: Corepressors are newly discovered assemblies of proteins that play essential roles in eukaryotic gene regulation. Recent discoveries about corepressors have provided new insights into the molecular basis of gene regulation, and have established surprising connections between the mechanisms of action of a wide variety of transcriptional regulators. The reviews in this volume critically discuss the nature, mechanisms of action, and physiological roles of corepressors in a diverse assortment of biological systems. Both basic and clinical investigators will be able to find relevant information. The comprehensive nature of the compilation, and the breadth of the reviews, are intended to provide the reader with an excellent introduction to the newly emergent and rapidly-growing field of corepressor research. A valuable and detailed reference guide.

Eukaryotic Transcription Factors

2003-11-21 Medical
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Release : 2003-11-21
Genre : Medical
Kind : eBook
Book Rating : 261/5 ( reviews)

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Book Synopsis Eukaryotic Transcription Factors by : David S. Latchman

Download or read book Eukaryotic Transcription Factors written by David S. Latchman. This book was released on 2003-11-21. Available in PDF, EPUB and Kindle. Book excerpt: Now in two-colour throughout, the fourth edition of Eukaryotic Transcription Factors has been completely rewritten and restructured to take into account the tremendous advances in our understanding of transcription factors and the mechanisms by which they act. Considerable emphasis has been given to the interaction between transcription factors and chromatin structure. Also included is an entirely new section on the mediator complex and expansion of the space devoted to co-activators and co-repressors.This book is essential reading for all those who wish to understand the impact of molecular biology on medicine, whatever their speciality. Major families of eukaryotic transcription factors described Mechanisms of gene activation and repression analysed Structure-function relationships indicated Interaction between transcription factors and chromatin structure described Roles in inducible and cell type-specific gene expression Roles in development, differentiation and human diseases including cancer Methods of study in vitro and in vivo

Transcriptional Corepressors: Mediators of Eukaryotic Gene Repressi

2000
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Release : 2000
Genre :
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Transcriptional Corepressors: Mediators of Eukaryotic Gene Repressi by : Martin L. Privalsky

Download or read book Transcriptional Corepressors: Mediators of Eukaryotic Gene Repressi written by Martin L. Privalsky. This book was released on 2000. Available in PDF, EPUB and Kindle. Book excerpt:

Transcriptional Corepressors

2014-01-15
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Release : 2014-01-15
Genre :
Kind : eBook
Book Rating : 962/5 ( reviews)

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Book Synopsis Transcriptional Corepressors by : Martin L. Privalsky

Download or read book Transcriptional Corepressors written by Martin L. Privalsky. This book was released on 2014-01-15. Available in PDF, EPUB and Kindle. Book excerpt:

CtBP Family Proteins

2011-01-05 Medical
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Release : 2011-01-05
Genre : Medical
Kind : eBook
Book Rating : 960/5 ( reviews)

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Book Synopsis CtBP Family Proteins by : G. Chinnadurai

Download or read book CtBP Family Proteins written by G. Chinnadurai. This book was released on 2011-01-05. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive monograph on the CtBP family proteins. These proteins are gaining wide scientific interest due to their critical roles in animal development and in oncogenesis. The CtBP family proteins are multifunctional. They predominantly function as transcriptional corepressors in the nucleus by recruiting various histone modifying enzymes such as histone deacetylases, histone methylases and a histone demethylase. They also perform several diverse cytosolic functions such as Golgi maintenance and in central nervous system synapses.

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