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Organ Tissue Engineering

2021-04-22 Technology & Engineering
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Release : 2021-04-22
Genre : Technology & Engineering
Kind : eBook
Book Rating : 101/5 ( reviews)

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Book Synopsis Organ Tissue Engineering by : Daniel Eberli

Download or read book Organ Tissue Engineering written by Daniel Eberli. This book was released on 2021-04-22. Available in PDF, EPUB and Kindle. Book excerpt: The notion of being able to engineer complete organs has inspired an entire generation of researchers. While recent years have brought significant progress in regenerative medicine and tissue engineering, the immense challenges encountered when trying to engineer an entire organ have to be acknowledged. Despite a good understanding of cell phenotypes, cellular niches and cell-to-biomaterial interactions, the formation of tissues composed of multiple cells remains highly challenging. Only a step-by-step approach will allow the future production of a living tissue construct ready for implantation and to augment organ function. In this book, expert authors present the current state of this approach. It offers a concise overview and serves as a great starting point for anyone interested in the application of tissue engineering or regenerative medicine for organ engineering. Each chapter contains a short overview including physiological and pathological changes as well as the current clinical need. The potential cell sources and suitable biomaterials for each organ type are discussed and possibilities to produce organ-like structures are illustrated. The ultimate goal is for the generated small tissues to unfold their full potential in vivo and to serve as a native tissue equivalent. By integrating and evolving, these implants will form functional tissue in-vivo. This book discusses the desired outcome by focusing on well-defined functional readouts. Each chapter addresses the status of clinical translations and closes with the discussion of current bottlenecks and an outlook for the coming years. A successful regenerative medicine approach could solve organ shortage by providing biological substitutes for clinical use - clearly, this merits a collaborative effort.

Biomaterials for Organ and Tissue Regeneration

2020-03-20 Medical
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Release : 2020-03-20
Genre : Medical
Kind : eBook
Book Rating : 071/5 ( reviews)

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Book Synopsis Biomaterials for Organ and Tissue Regeneration by : Nihal Vrana

Download or read book Biomaterials for Organ and Tissue Regeneration written by Nihal Vrana. This book was released on 2020-03-20. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials for Organ and Tissue Regeneration: New Technologies and Future Prospects examines the use of biomaterials in applications related to artificial tissues and organs. With a strong focus on fundamental and traditional tissue engineering strategies, the book also examines how emerging and enabling technologies are being developed and applied. Sections provide essential information on biomaterial, cell properties and cell types used in organ generation. A section on state-of-the-art in organ regeneration for clinical purposes is followed by a discussion on enabling technologies, such as bioprinting, on chip organ systems and in silico simulations. Provides a systematic overview of the field, from fundamentals, to current challenges and opportunities Encompasses the classic paradigm of tissue engineering for creation of new functional tissue Discusses enabling technologies such as bioprinting, organ-on-chip systems and in silico simulations

Tissue and Organ Regeneration in Adults

2014-11-21 Technology & Engineering
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Release : 2014-11-21
Genre : Technology & Engineering
Kind : eBook
Book Rating : 656/5 ( reviews)

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Book Synopsis Tissue and Organ Regeneration in Adults by : Ioannis V. Yannas

Download or read book Tissue and Organ Regeneration in Adults written by Ioannis V. Yannas. This book was released on 2014-11-21. Available in PDF, EPUB and Kindle. Book excerpt: This textbook describes the basic principles of induced organ regeneration in skin and peripheral nerves and extends the original successful paradigm to other organs. A set of trans-organ rules is established and its use in regeneration of several organs is illustrated from the works of several independent investigators who worked with a variety of organs, such as the lung, the bladder, and the Achilles tendon, using collagen-based scaffolds somewhat similar to the original one. These critical medical treatments fill the clinical need that is not met by organ transplantation. New to this second edition: New information extending the paradigm of tissue regeneration from organ regeneration in skin and peripheral nerves to other organs Guidelines, known as trans-organ rules, are described for the first time for extending this unique medical treatment to organs of several medical specialties The work serves as a comprehensive text and reference for students and practitioners of tissue engineering

Fundamentals of Tissue Engineering and Regenerative Medicine

2009-02-11 Medical
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Release : 2009-02-11
Genre : Medical
Kind : eBook
Book Rating : 555/5 ( reviews)

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Book Synopsis Fundamentals of Tissue Engineering and Regenerative Medicine by : Ulrich Meyer

Download or read book Fundamentals of Tissue Engineering and Regenerative Medicine written by Ulrich Meyer. This book was released on 2009-02-11. Available in PDF, EPUB and Kindle. Book excerpt: "Fundamentals of Tissue Engineering and Regenerative Medicine" provides a complete overview of the state of the art in tissue engineering and regenerative medicine. Tissue engineering has grown tremendously during the past decade. Advances in genetic medicine and stem cell technology have significantly improved the potential to influence cell and tissue performance, and have recently expanded the field towards regenerative medicine. In recent years a number of approaches have been used routinely in daily clinical practice, others have been introduced in clinical studies, and multitudes are in the preclinical testing phase. Because of these developments, there is a need to provide comprehensive and detailed information for researchers and clinicians on this rapidly expanding field. This book offers, in a single volume, the prerequisites of a comprehensive understanding of tissue engineering and regenerative medicine. The book is conceptualized according to a didactic approach (general aspects: social, economic, and ethical considerations; basic biological aspects of regenerative medicine: stem cell medicine, biomolecules, genetic engineering; classic methods of tissue engineering: cell, tissue, organ culture; biotechnological issues: scaffolds; bioreactors, laboratory work; and an extended medical discipline oriented approach: review of clinical use in the various medical specialties). The content of the book, written in 68 chapters by the world’s leading research and clinical specialists in their discipline, represents therefore the recent intellect, experience, and state of this bio-medical field.

Tissue Engineering for Tissue and Organ Regeneration

2011-08-17 Technology & Engineering
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Release : 2011-08-17
Genre : Technology & Engineering
Kind : eBook
Book Rating : 887/5 ( reviews)

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Book Synopsis Tissue Engineering for Tissue and Organ Regeneration by : Daniel Eberli

Download or read book Tissue Engineering for Tissue and Organ Regeneration written by Daniel Eberli. This book was released on 2011-08-17. Available in PDF, EPUB and Kindle. Book excerpt: Tissue Engineering may offer new treatment alternatives for organ replacement or repair deteriorated organs. Among the clinical applications of Tissue Engineering are the production of artificial skin for burn patients, tissue engineered trachea, cartilage for knee-replacement procedures, urinary bladder replacement, urethra substitutes and cellular therapies for the treatment of urinary incontinence. The Tissue Engineering approach has major advantages over traditional organ transplantation and circumvents the problem of organ shortage. Tissues reconstructed from readily available biopsy material induce only minimal or no immunogenicity when reimplanted in the patient. This book is aimed at anyone interested in the application of Tissue Engineering in different organ systems. It offers insights into a wide variety of strategies applying the principles of Tissue Engineering to tissue and organ regeneration.

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