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The Rational Design of Protein Solutions

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Author :
Release : 2007
Genre :
Kind : eBook
Book Rating : 697/5 ( reviews)

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Book Synopsis The Rational Design of Protein Solutions by : Thomas F. O'Connor

Download or read book The Rational Design of Protein Solutions written by Thomas F. O'Connor. This book was released on 2007. Available in PDF, EPUB and Kindle. Book excerpt: The effects of cosolutes on protein stability were further studied using simulations of a simple "HP" protein in the presence of solute molecules that are devoid of enthalpic interactions. It was found that entropic interactions were able to account for the increase in stability of our model protein as well as the exclusion of solute molecules from the protein surface. This simulation study also examined the impact of cosolute size and shape on its ability to stabilize the native state of the model protein.

Rational Design of Stable Protein Formulations

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Author :
Release : 2012-12-06
Genre : Medical
Kind : eBook
Book Rating : 577/5 ( reviews)

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Book Synopsis Rational Design of Stable Protein Formulations by : John F. Carpenter

Download or read book Rational Design of Stable Protein Formulations written by John F. Carpenter. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: Recombinant proteins and polypeptides continue to be the most important class of biotechnology-derived agents in today's pharmaceutical industry. Over the past few years, our fundamental understanding of how proteins degrade and how stabilizing agents work has made it possible to approach formulation of protein pharmaceuticals from a much more rational point of view. This book describes the current level of understanding of protein instability and the strategies for stabilizing proteins under a variety of stressful conditions.

Rational Design of Protein Function

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Author :
Release : 2002
Genre : Proteins
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Rational Design of Protein Function by : Michael Scott Wisz

Download or read book Rational Design of Protein Function written by Michael Scott Wisz. This book was released on 2002. Available in PDF, EPUB and Kindle. Book excerpt:

Computational Protein Design

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Author :
Release : 2016-12-03
Genre : Science
Kind : eBook
Book Rating : 356/5 ( reviews)

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Book Synopsis Computational Protein Design by : Ilan Samish

Download or read book Computational Protein Design written by Ilan Samish. This book was released on 2016-12-03. Available in PDF, EPUB and Kindle. Book excerpt: The aim this volume is to present the methods, challenges, software, and applications of this widespread and yet still evolving and maturing field. Computational Protein Design, the first book with this title, guides readers through computational protein design approaches, software and tailored solutions to specific case-study targets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Protein Design aims to ensure successful results in the further study of this vital field.

Protein Engineering

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Author :
Release : 1994
Genre :
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Protein Engineering by :

Download or read book Protein Engineering written by . This book was released on 1994. Available in PDF, EPUB and Kindle. Book excerpt:

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