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The Blood-Brain Barrier in Health and Disease, Volume Two

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Release : 2015-10-21
Genre : Medical
Kind : eBook
Book Rating : 093/5 ( reviews)

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Book Synopsis The Blood-Brain Barrier in Health and Disease, Volume Two by : Katerina Dorovini-Zis

Download or read book The Blood-Brain Barrier in Health and Disease, Volume Two written by Katerina Dorovini-Zis. This book was released on 2015-10-21. Available in PDF, EPUB and Kindle. Book excerpt: Located at the interface between blood and the brain, the blood-brain barrier is a dynamic permeability barrier formed by a continuous layer of specialized endothelial cells endowed with important permeability, transport, and regulatory functions that both protect the internal milieu of the brain and allow essential nutrients to be transported into

The Blood-Brain Barrier in Health and Disease

Download The Blood-Brain Barrier in Health and Disease PDF Online Free

Author :
Release : 2015-10-15
Genre : Medical
Kind : eBook
Book Rating : 082/5 ( reviews)

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Book Synopsis The Blood-Brain Barrier in Health and Disease by : Katerina Dorovini-Zis

Download or read book The Blood-Brain Barrier in Health and Disease written by Katerina Dorovini-Zis. This book was released on 2015-10-15. Available in PDF, EPUB and Kindle. Book excerpt: Located at the interface between blood and the brain, the blood-brain barrier is a dynamic permeability barrier formed by a continuous layer of specialized endothelial cells endowed with important permeability, transport, and regulatory functions that both protect the internal milieu of the brain and allow essential nutrients to be transported into the brain. Abnormalities of the blood-brain barrier are increasingly recognized as a key component in the pathogenesis of a range of primary diseases of the brain and the secondary involvement of the brain from pathological processes in other organs. In The Blood-Brain Barrier in Health and Disease, Volume 2, international experts present comprehensive reviews and research accounts on blood-brain barrier dysfunction in infectious and inflammatory diseases, cerebrovascular diseases, stroke, trauma, vitamin deficiency, exposure to neurotoxicants, primary and metastatic brain tumors, and neurodegenerative diseases. This book is intended to serve as a guide and reference to basic and advanced information for researchers, students, and clinicians interested in this fast-expanding field and stimulate further research well into the future.

The Blood-Brain Barrier in Health and Disease, Volume One

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Author :
Release : 2015-06-23
Genre : Medical
Kind : eBook
Book Rating : 069/5 ( reviews)

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Book Synopsis The Blood-Brain Barrier in Health and Disease, Volume One by : Katerina Dorovini-Zis

Download or read book The Blood-Brain Barrier in Health and Disease, Volume One written by Katerina Dorovini-Zis. This book was released on 2015-06-23. Available in PDF, EPUB and Kindle. Book excerpt: Located at the interface between blood and the brain, the blood-brain barrier is a dynamic permeability barrier formed by a continuous layer of specialized endothelial cells endowed with important permeability, transport, and regulatory functions that both protect the internal milieu of the brain and allow essential nutrients to be transported into

Blood-Spinal Cord and Brain Barriers in Health and Disease

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Author :
Release : 2004
Genre : Medical
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Blood-Spinal Cord and Brain Barriers in Health and Disease by : Hari Shanker Sharma

Download or read book Blood-Spinal Cord and Brain Barriers in Health and Disease written by Hari Shanker Sharma. This book was released on 2004. Available in PDF, EPUB and Kindle. Book excerpt: Recent research into the anatomy and pathophysiology of the blood-brain and blood-spinal cord barriers suggests that a breakdown in these barriers can result in several diseases affecting the central nervous system (CNS). This book presents new findings in the area of blood-brain barrier research that suggest barriers play important roles in health and disease conditions. It also discusses the development of new drugs that can modulate the barrier function in the CNS and may provide new approaches to treating neurological diseases such as Alzheimer's disease and other motor neuron diseases, as well as spinal cord trauma. Key Features * Presents the recent progress made in the research on the blood-brain and spinal cord barrier * Contains numerous illustrations of light and electron micrographs * Includes Foreword written by two eminent researchers in the field, Milton Brightman and Jorge Cervos-Navarro

The Blood-Brain Barrier in Health and Disease

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Author :
Release : 2016-12-15
Genre : Medical
Kind : eBook
Book Rating : 409/5 ( reviews)

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Book Synopsis The Blood-Brain Barrier in Health and Disease by : William G. Mayhan

Download or read book The Blood-Brain Barrier in Health and Disease written by William G. Mayhan. This book was released on 2016-12-15. Available in PDF, EPUB and Kindle. Book excerpt: The blood-brain barrier (BBB) is a complex and dynamic structure that protects the brain from cells within the vasculature, from the immune system and from pathogens. This barrier is present in arterioles, capillaries and venules and is formed at the level of adjacent endothelial cells, which are coupled to astrocytes, microglia, neurons and pericytes. The structure of this endothelial barrier is unique among endothelia of other organ systems and is composed of complexes made up of tight, gap and adherens junctions. In addition, it is the responsibility of the surrounding cellular elements to maintain the integrity of the junctional complexes and restrict the entry of substances from the blood into the brain. Changes in permeability of the BBB during physiologic and pathophysiologic conditions involve alterations in specific transporters at the level of the endothelium, activation of specific cellular second messenger pathways and/or the dissolution of the junctional complexes composing the BBB. This book focuses on various aspects that account for the formation and maintenance of the BBB, and on disease states that compromise this barrier.

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