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The Biosynthesis of Secondary Metabolites

2012-12-06 Science
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Release : 2012-12-06
Genre : Science
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Book Rating : 331/5 ( reviews)

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Book Synopsis The Biosynthesis of Secondary Metabolites by : R. B. Herbert

Download or read book The Biosynthesis of Secondary Metabolites written by R. B. Herbert. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: This is a book about experiments and results of experiments. The results described are the fruit of thirty years' labour in the field of secondary metabolism. Secondary metabolism, more than any other part of the chemistry of life, has been the special preserve of organic chemists. Investiga tion of secondary metabolism began with curiosity about the struc tures of compounds isolated from natural sources, i.e. secondary metabolites. Coeval with structure determination there has been a curiosity about the origins and mechanism of formation of secondary metabolites (or natural products as they have been called). It is the experimental outcome of this curiosity that is described here. This account is primarily intended to be an introduction to the biosynthesis of secondary metabolites. I have also endeavoured, however, to make the book as comprehensive as possIble. This has meant that some of the material has had to be presented in abbrevi ated form. The abbreviated material is largely confined to particular sections of the book. The paragraphs marked with a dagger (t) can be omitted by the reader wishing to acquire a general introduction to the subject. A blend of the most significant and the most recent references is cited to provide the reader with ready access to the primary litera ture. This is clearly most necessary for the material presented in abbreviated form. Relevant reviews are also cited.

The Biosynthesis of Secondary Metabolites

1989-03-31 Science
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Release : 1989-03-31
Genre : Science
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Book Rating : 207/5 ( reviews)

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Book Synopsis The Biosynthesis of Secondary Metabolites by : R.B. Herbert

Download or read book The Biosynthesis of Secondary Metabolites written by R.B. Herbert. This book was released on 1989-03-31. Available in PDF, EPUB and Kindle. Book excerpt: The chief purpose of such new editions is to bring the text up to date. This I have tried to do. The danger with such endeavours is that the book becomes corpulent. This I have tried to avoid. In so doing I am evermore conscious of how much material has had to be omitted. As before the references (ca. 770 of them) which are cited are intended in part to provide the reader with access to material that has been omitted. I am deeply grateful to Mrs Marjorie Romanowicz for preparing the typed manuscript for this edition with customary accuracy and efficiency, to my wife Margaret for checking the references, and to research students Karl Cable, Lucy Hyatt, Mashupye Kgaphola and Andrew Knaggs for helping with the checking of the manuscript. Richard Herbert April 1988 Preface to the first edition This is a book about experiments and results of experiments. The results described are the fruit of thirty years' labour in the field of secondary metabolism. Secondary metabolism, more than any other part of the chemistry of life, has been the special preserve of organic chemists. Investigation of secondary metabolism began with curiosity about the structures of compounds isolated from natural sources, i.e. secondary metabolites. Coeval with structure determination there has been a curiosity about the origins and mechanism of formation of secondary metabolites (or natural products as they have been called). It is the experimental outcome of this curiosity that is described here.

Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2

2015-06-15 Science
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Release : 2015-06-15
Genre : Science
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Book Rating : 318/5 ( reviews)

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Book Synopsis Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2 by : Susanne Zeilinger

Download or read book Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2 written by Susanne Zeilinger. This book was released on 2015-06-15. Available in PDF, EPUB and Kindle. Book excerpt: ​Fungi produce many chemically diverse secondary metabolites whose biological roles largely remain elusive. Within the increasing number of sequenced fungal genomes several important genes involved in secondary metabolite formation have been identified. Most of these genes are clustered and their coordinated transcription is controlled in a complex way by both narrow pathway-specific regulators as well as broad global transcription factors responsive to environmental cues. In recent years it was discovered many of the newly identified gene clusters are silent under laboratory conditions suggesting that the biosynthetic potential of fungi is far from being exploited. Besides identifying novel bioactive metabolites from still unexplored sources, the activation of these gene clusters by several approaches may result in the discovery of new substances with antibiotic and pharmaceutical benefits. This book covers recent advances in the field of fungal secondary metabolisms ranging from methodologies to biological aspects and will include the latest knowledge on fungal molecular biology, genomics, and metabolomics. With the related volume by Professor Juan-Francisco Martin, where the most relevant and well-studied fungal secondary metabolites are compiled, this book provides a comprehensive overview of the state-of-the-art of research on fungal secondary metabolites.

Secondary Metabolism in Microorganisms, Plants, and Animals

1984 Medical
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Release : 1984
Genre : Medical
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Book Synopsis Secondary Metabolism in Microorganisms, Plants, and Animals by : Martin Luckner

Download or read book Secondary Metabolism in Microorganisms, Plants, and Animals written by Martin Luckner. This book was released on 1984. Available in PDF, EPUB and Kindle. Book excerpt: General aspects. Methods used in the investigation of secondary metabolism. Important groups of secondary metabolic enzymes. Structure, biosynthesis, and metabolism of secondary products in microorganisms, plants, and animals. The significance of secondary metabolism and secondary products for the producer organisms.

Plant Secondary Metabolism

2012-12-06 Science
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Release : 2012-12-06
Genre : Science
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Book Rating : 132/5 ( reviews)

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Book Synopsis Plant Secondary Metabolism by : David S. Seigler

Download or read book Plant Secondary Metabolism written by David S. Seigler. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: Life has evolved as a unified system; no organism exists similar role also has been suggested for fatty acids from alone, but each is in intimate contact with other organisms cyanolipids. Nonprotein amino acids, cyanogenic glyco and its environment. Historically, it was easier for workers sides, and the non-fatty-acid portion of cyanolipids also are in various disciplines to delimit artificially their respective incorporated into primary metabolites during germination. areas of research, rather than attempt to understand the entire Secondary metabolites of these structural types are accumu system of living organisms. This was a pragmatic and neces lated in large quantities in the seeds of several plant groups sary way to develop an understanding for the various parts. where they probably fulfill an additional function as deter We are now at a point, however, where we need to investi rents to general predation. gate those things common to the parts and, specifically, those The second type of relationship involves interaction of things that unify the parts. The fundamental aspects of many plants with other organisms and with their environment. Bio of these interactions are chemical in nature. Plants constitute logical interactions must be viewed in the light of evolution an essential part of all life systems; phytochemistry provides ary change and the coadaptation, or perhaps coevolution, of a medium for linking several fields of study.

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