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The Benefits of Natural Products for Neurodegenerative Diseases

2016-09-20 Medical
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Release : 2016-09-20
Genre : Medical
Kind : eBook
Book Rating : 839/5 ( reviews)

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Book Synopsis The Benefits of Natural Products for Neurodegenerative Diseases by : M. Mohamed Essa

Download or read book The Benefits of Natural Products for Neurodegenerative Diseases written by M. Mohamed Essa. This book was released on 2016-09-20. Available in PDF, EPUB and Kindle. Book excerpt: Focuses on the effects of natural products and their active components on brain function and neurodegenerative disease prevention. Phytochemicals such as alkaloids, terpenes, flavanoids, isoflavones, saponins etc are known to possess protective activity against many neurological diseases. The molecular mechanisms behind the curative effects rely mainly on the action of phytonutrients on distinct signaling pathways associated with protein folding and neuro-inflammation. The diverse array of bioactive nutrients present in these natural products plays a pivotal role in prevention and cure of various neurodegenerative diseases, disorders, or insults, such as Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, traumatic brain injury, and other neuronal dysfunctions. However, the use of these antioxidants in the management of neurodegenerative conditions has so far been not well understood. This is a comprehensive collection addressing the effects on the brain of natural products and edible items such as reservatrol, curcumin, gingerol, fruits, vegetables, nuts, and marine products.

Natural Products and Neuroprotection

2020-06-17 Science
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Release : 2020-06-17
Genre : Science
Kind : eBook
Book Rating : 16X/5 ( reviews)

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Book Synopsis Natural Products and Neuroprotection by : Cristina Angeloni

Download or read book Natural Products and Neuroprotection written by Cristina Angeloni. This book was released on 2020-06-17. Available in PDF, EPUB and Kindle. Book excerpt: Neurodegenerative diseases, including Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis, are the most common pathologies of the central nervous system currently without a cure. They share common molecular and cellular characteristics, including protein misfolding, mitochondrial dysfunction, glutamate toxicity, dysregulation of calcium homeostasis, oxidative stress, inflammation, and ageing, which contribute to neuronal death. Efforts to treat these diseases are often limited by their multifactorial etiology. Natural products, thanks to their multitarget activities, are considered promising alternatives for the treatment of neurodegeneration. This book deals with two different forms of natural products: extracts and isolated compounds. The study of the bioactivity of the extracts is extremely important as many studies have demonstrated the synergistic effect of the combination of different natural products. On the other hand, the investigation of the activity of specifically isolated natural products can be also important to understand their cellular and molecular mechanisms and to define the specific bioactive components in extracts or foods. This book can be considered an important contribution to knowledge of the neuroprotective effect of natural products and presents a great deal of information, related to both the benefits but also the limitations of their use in counteracting neurodegeneration.

Neuroprotective Natural Products

2017-03-03 Medical
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Release : 2017-03-03
Genre : Medical
Kind : eBook
Book Rating : 793/5 ( reviews)

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Book Synopsis Neuroprotective Natural Products by : Goutam Brahmachari

Download or read book Neuroprotective Natural Products written by Goutam Brahmachari. This book was released on 2017-03-03. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on the molecular mechanisms of powerful naturally occurring agents and their implication for drug discovery, this timely book presents an overview of the most recent research advances in the field of bioactive natural products and natural drug formulations to combat today's destructive diseases. To this extent, the authors discuss the most severe neurological disorders in our modern civilization, such as Alzheimer's, Parkinson's and Huntington's disease, as well as ischemic brain stroke and depression. The emerging diversity of active compounds is covered in detail, including flavonoids, cannabinoids and oleanolic acid, while experts in the field explain the chemistry, mode of action and clinical aspects of novel neuroprotective natural products. In each case, the benefits of treatments using natural products are addressed from the perspective of modern as well as traditional medicine. With its multidisciplinary viewpoint, this is the ideal companion for medicinal and natural products chemists as well as neuroscientists, biochemists, pharmacologists, neurobiologists, and phytotherapists.

Natural Products and Neuroprotection

2020
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Release : 2020
Genre :
Kind : eBook
Book Rating : 172/5 ( reviews)

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Book Synopsis Natural Products and Neuroprotection by : Cristina Angeloni

Download or read book Natural Products and Neuroprotection written by Cristina Angeloni. This book was released on 2020. Available in PDF, EPUB and Kindle. Book excerpt: Neurodegenerative diseases, including Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis, are the most common pathologies of the central nervous system currently without a cure. They share common molecular and cellular characteristics, including protein misfolding, mitochondrial dysfunction, glutamate toxicity, dysregulation of calcium homeostasis, oxidative stress, inflammation, and ageing, which contribute to neuronal death. Efforts to treat these diseases are often limited by their multifactorial etiology. Natural products, thanks to their multitarget activities, are considered promising alternatives for the treatment of neurodegeneration. This book deals with two different forms of natural products: extracts and isolated compounds. The study of the bioactivity of the extracts is extremely important as many studies have demonstrated the synergistic effect of the combination of different natural products. On the other hand, the investigation of the activity of specifically isolated natural products can be also important to understand their cellular and molecular mechanisms and to define the specific bioactive components in extracts or foods. This book can be considered an important contribution to knowledge of the neuroprotective effect of natural products and presents a great deal of information, related to both the benefits but also the limitations of their use in counteracting neurodegeneration.

Natural Products-Based Drugs: Potential Therapeutics against Alzheimer's Disease and other Neurological Disorders

2020-01-27
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Release : 2020-01-27
Genre :
Kind : eBook
Book Rating : 489/5 ( reviews)

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Book Synopsis Natural Products-Based Drugs: Potential Therapeutics against Alzheimer's Disease and other Neurological Disorders by : Muhammad Ayaz

Download or read book Natural Products-Based Drugs: Potential Therapeutics against Alzheimer's Disease and other Neurological Disorders written by Muhammad Ayaz. This book was released on 2020-01-27. Available in PDF, EPUB and Kindle. Book excerpt:

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