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Textbook of Drug Design and Discovery, Third Edition

2002-07-25 Medical
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Release : 2002-07-25
Genre : Medical
Kind : eBook
Book Rating : 888/5 ( reviews)

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Book Synopsis Textbook of Drug Design and Discovery, Third Edition by : Tommy Liljefors

Download or read book Textbook of Drug Design and Discovery, Third Edition written by Tommy Liljefors. This book was released on 2002-07-25. Available in PDF, EPUB and Kindle. Book excerpt: Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The book follows drug design from the initial lead identification through optimization and structure-activity relationship with reference to the final processes of clinical evaluation and registration. Chapters investigate the design of enzyme inhibitors and drugs for particular cellular targets such as ion channels and receptors, and also explore specific classes of drug such as peptidomimetics, antivirals and anticancer agents. The use of gene technology in pharmaceutical research, computer modeling techniques, and combinatorial approaches are also included.

Drug Discovery and Development, Third Edition

2019-12-13 Medical
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Release : 2019-12-13
Genre : Medical
Kind : eBook
Book Rating : 136/5 ( reviews)

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Book Synopsis Drug Discovery and Development, Third Edition by : James J. O'Donnell

Download or read book Drug Discovery and Development, Third Edition written by James J. O'Donnell. This book was released on 2019-12-13. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery and Development, Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It explores many scientific advances in new drug discovery and development for areas such as screening technologies, biotechnology approaches, and evaluation of efficacy and safety of drug candidates through preclinical testing. This book also greatly expands the focus on the clinical pharmacology, regulatory, and business aspects of bringing new drugs to the market and offers coverage of essential topics for companies involved in drug development. Historical perspectives and predicted trends are also provided. Features: Highlights emerging scientific fields relevant to drug discovery such as the microbiome, nanotechnology, and cancer immunotherapy; and novel research tools such as CRISPR and DNA-encoded libraries Case study detailing the discovery of the anti-cancer drug, lorlatinib Venture capitalist commentary on trends and best practices in drug discovery and development Comprehensive review of regulations and their impact on drug development, highlighting special populations, orphan drugs, and pharmaceutical compounding Multidiscipline functioning of an Academic Research Enterprise, plus a chapter on Ethical Concerns in Research Contributions by 70+ experts from industry and academia specialists who developed and are practitioners of the science and business

Textbook of Drug Design and Discovery

2009-10-07 Medical
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Release : 2009-10-07
Genre : Medical
Kind : eBook
Book Rating : 401/5 ( reviews)

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Book Synopsis Textbook of Drug Design and Discovery by : Kristian Stromgaard

Download or read book Textbook of Drug Design and Discovery written by Kristian Stromgaard. This book was released on 2009-10-07. Available in PDF, EPUB and Kindle. Book excerpt: The molecular biological revolution and the mapping of the human genome continue to provide new challenges and opportunities for drug research and design. Future medicinal chemists and drug designers must have a firm background in a number of related scientific disciplines in order to understand the conversion of new insight into lead structures an

Drug Discovery and Development

2021-05-16 Medical
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Release : 2021-05-16
Genre : Medical
Kind : eBook
Book Rating : 050/5 ( reviews)

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Book Synopsis Drug Discovery and Development by : Raymond G Hill

Download or read book Drug Discovery and Development written by Raymond G Hill. This book was released on 2021-05-16. Available in PDF, EPUB and Kindle. Book excerpt: With unprecedented interest in the power that the modern therapeutic armamentarium has to combat disease, the new edition of Drug Discovery and Development is an essential resource for anyone interested in understanding how drugs and other therapeutic interventions are discovered and developed, through to clinical research, registration, and market access. The text has been thoroughly updated, with new information on biopharmaceuticals and vaccines as well as clinical development and target identification. Drug discovery and development continues to evolve rapidly and this new edition reflects important changes in the landscape. Edited by industry experts Raymond Hill and Duncan Richards, this market-leading text is suitable for undergraduates and graduates undertaking degrees in pharmacy, pharmacology, toxicology, and clinical development through to those embarking on a career in the pharmaceutical industry. Key stages of drug discovery and development Chapters outline the contribution of individual disciplines to the overall process Supplemented by specific chapters on different modalities Includes coverage of Oligonucleotide therapies; cell and gene therapy Now comes with online access on StudentConsult

The Organic Chemistry of Drug Design and Drug Action

2012-12-02 Science
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Release : 2012-12-02
Genre : Science
Kind : eBook
Book Rating : 379/5 ( reviews)

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Book Synopsis The Organic Chemistry of Drug Design and Drug Action by : Richard B. Silverman

Download or read book The Organic Chemistry of Drug Design and Drug Action written by Richard B. Silverman. This book was released on 2012-12-02. Available in PDF, EPUB and Kindle. Book excerpt: Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization

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