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Targeted Drug Delivery : Concepts and Design

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Release : 2014-12-08
Genre : Medical
Kind : eBook
Book Rating : 550/5 ( reviews)

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Book Synopsis Targeted Drug Delivery : Concepts and Design by : Padma V. Devarajan

Download or read book Targeted Drug Delivery : Concepts and Design written by Padma V. Devarajan. This book was released on 2014-12-08. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.

Drug Targeting And Delivery

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Release : 1992-10-31
Genre : Medical
Kind : eBook
Book Rating : 682/5 ( reviews)

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Book Synopsis Drug Targeting And Delivery by : H.E. Junginger

Download or read book Drug Targeting And Delivery written by H.E. Junginger. This book was released on 1992-10-31. Available in PDF, EPUB and Kindle. Book excerpt: This is a review of the structure and function of biological membranes and other cellular barriers used in drug transport. It discusses a range of concepts for drug delivery systems, treating the routes of drugs with regard to their characteristics: function, structure, uptake, mechanism and effect. The book also explores the interface between pharmaceutical technology and physiological principles in drug design, a field of increased importance to industry.

Advanced Drug Delivery

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Release : 2013-08-26
Genre : Medical
Kind : eBook
Book Rating : 849/5 ( reviews)

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Book Synopsis Advanced Drug Delivery by : Ashim Mitra

Download or read book Advanced Drug Delivery written by Ashim Mitra. This book was released on 2013-08-26. Available in PDF, EPUB and Kindle. Book excerpt: Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases. Advanced Drug Delivery features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts: Part I, Introduction and Basics of Advanced Drug Delivery, explores physiological barriers, stability, transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offers tested and proven strategies for advanced delivery of both small molecules and macromolecules Part III, Translational Research of Advanced Drug Delivery, focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas, examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging Each chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book. Advanced Drug Delivery is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.

Design of Controlled Release Drug Delivery Systems

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Release : 2005-11-24
Genre : Technology & Engineering
Kind : eBook
Book Rating : 833/5 ( reviews)

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Book Synopsis Design of Controlled Release Drug Delivery Systems by : Xiaoling Li

Download or read book Design of Controlled Release Drug Delivery Systems written by Xiaoling Li. This book was released on 2005-11-24. Available in PDF, EPUB and Kindle. Book excerpt: The goal of every drug delivery system is to deliver the precise amount of a drug at a pre-programmed rate to the desired location in order to achieve the drug level necessary for the treatment. An essential guide for biomedical engineers and pharmaceutical designers, this resource combines physicochemical principles with physiological processes to facilitate the design of systems that will deliver medication at the time and place it is most needed.

Targeted Drug Delivery

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Release : 2012-12-06
Genre : Medical
Kind : eBook
Book Rating : 622/5 ( reviews)

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Book Synopsis Targeted Drug Delivery by : Rudolph L. Juliano

Download or read book Targeted Drug Delivery written by Rudolph L. Juliano. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: The chapters in this volume describe a powerful emerging approach for the therapy of disease. Targeted drug delivery, that is control of the kinetic behavior, tissue distribution, and subcellular localization of pharmaco logically active agents, offers an important means for improving the efficacy of a wide variety of drug therapies. This is particularly true for therapeutic approaches based on newer agents which are the products of recombinant DNA research. These agents, be they peptides, proteins, or oligonucleotides, tend to be larger, more complex, and less stable than traditional drugs. Thus they stand to benefit most from drug delivery systems which can protect them from premature degradation and which can carry them to critical target sites in the body. This volume examines several important aspects of the current state of drug delivery research; it also attempts to project future directions for this field. Successful approaches to drug targeting are based, first of all, on a sophisticated understanding of the biological barriers encountered by the drug-carrier complex as it moves from the portal of administration to the ultimate target site. A second aspect of successful drug delivery is appro priate matching of the disease entity with the pharmacologically active substance and with the delivery system. Thus it is important to be aware of the variety of delivery technologies which currently exist and to be sensitive to their strengths and limitations.

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