Share

Systems for Research and Evaluation for Translating Genome-Based Discoveries for Health

2009-11-10 Medical
Download Systems for Research and Evaluation for Translating Genome-Based Discoveries for Health PDF Online Free

Author :
Release : 2009-11-10
Genre : Medical
Kind : eBook
Book Rating : 417/5 ( reviews)

GET EBOOK


Book Synopsis Systems for Research and Evaluation for Translating Genome-Based Discoveries for Health by : Institute of Medicine

Download or read book Systems for Research and Evaluation for Translating Genome-Based Discoveries for Health written by Institute of Medicine. This book was released on 2009-11-10. Available in PDF, EPUB and Kindle. Book excerpt: With the advent of genome-wide association studies, numerous associations between specific gene loci and complex diseases have been identified-for breast cancer, coronary artery disease, and asthma, for example. This rapidly advancing field of genomics has stirred great interest in "personalized" health care from both the public and private sectors. The hope is that using genomic information in clinical care will lead to reduced health care costs and improved health outcomes as therapies are tailored to the genetic susceptibilities of patients. A variety of genetically based health care innovations have already reached the marketplace, but information about the clinical use of these treatments and diagnostics is limited. Currently data do not provide information about how a genomic test impacts clinical care and patient health outcomes-other approaches are needed to garner such information. This volume summarizes a workshop to address central questions related to the development of systems to evaluate clinical use of health care innovations that stem from genome-based research: What are the practical realities of creating such systems? What different models could be used? What are the strengths and weaknesses of each model? How effectively can such systems address questions about health outcomes?

Diffusion and Use of Genomic Innovations in Health and Medicine

2008-06-18 Medical
Download Diffusion and Use of Genomic Innovations in Health and Medicine PDF Online Free

Author :
Release : 2008-06-18
Genre : Medical
Kind : eBook
Book Rating : 312/5 ( reviews)

GET EBOOK


Book Synopsis Diffusion and Use of Genomic Innovations in Health and Medicine by : Institute of Medicine

Download or read book Diffusion and Use of Genomic Innovations in Health and Medicine written by Institute of Medicine. This book was released on 2008-06-18. Available in PDF, EPUB and Kindle. Book excerpt: Until fairly recently, genetic information was used primarily in the diagnosis of relatively rare genetic diseases, such as cystic fibrosis and Huntington's Disease, but a transformation in the use of genetic and genomic information is underway. While many predictions have been made that genomics will transform medicine, to date few of these promising discoveries have resulted in actual applications in medicine and health. The Institute of Medicine's Roundtable on Translating Genomic-Based Research for Health, established in 2007, held its first workshop to address the following questions: 1. Are there different pathways by which new scientific findings move from the research setting into health care? 2. If so, what are the implications of those different pathways for genomics? 3. What can we learn from the translation of other new technologies as we seek to understand the translation of genome science into health care? Information obtained from the workshop was then used to further discussion and exploration of the answers to these questions. This book summarizes speaker presentations and discussions. Any conclusions reported should not be construed as reflecting a group consensus; rather they are the statements and opinions of presenters and participants.

Genetic Epidemiology

2013 Medical
Download Genetic Epidemiology PDF Online Free

Author :
Release : 2013
Genre : Medical
Kind : eBook
Book Rating : 818/5 ( reviews)

GET EBOOK


Book Synopsis Genetic Epidemiology by : Melissa A. Austin

Download or read book Genetic Epidemiology written by Melissa A. Austin. This book was released on 2013. Available in PDF, EPUB and Kindle. Book excerpt: Genetic epidemiology plays a key role in discovering genetic factors influencing health and disease, and in understanding how genes and environmental risk factors interact. There is growing interest in this field within public health, with the goal of translating the results into promoting health and preventing disease in both families and populations. This textbook provides graduate students with a working knowledge of genetic epidemiology research methods. Following an overview of the field, the book reviews key genetic concepts, provides an update on relevant genomic technology, including genome-wide chips and DNA sequencing, and describes methods for assessing the magnitude of genetic influences on diseases and risk factors. The book focuses on research study designs for discovering disease susceptibility genes, including family-based linkage analysis, candidate gene and genome-side association studies, assessing gene-environment interactions and epistasis, studies of Non-Mendelian inheritance, and statistical analyses of data from these studies. Specific applications of each research method are illustrated using a variety of diseases and risk factors relevant to public health, and useful web-based genetic analysis software, human reference panels, and repositories, that can greatly facilitate this work, are described.

Innovations in Service Delivery in the Age of Genomics

2009-06-11 Medical
Download Innovations in Service Delivery in the Age of Genomics PDF Online Free

Author :
Release : 2009-06-11
Genre : Medical
Kind : eBook
Book Rating : 142/5 ( reviews)

GET EBOOK


Book Synopsis Innovations in Service Delivery in the Age of Genomics by : Institute of Medicine

Download or read book Innovations in Service Delivery in the Age of Genomics written by Institute of Medicine. This book was released on 2009-06-11. Available in PDF, EPUB and Kindle. Book excerpt: New discoveries in genomics-that is, the study of the entire human genome-are changing how we diagnose and treat diseases. As the trend shifts from genetic testing largely being undertaken for rare genetic disorders to, increasingly, individuals being screened for common diseases, general practitioners, pediatricians, obstetricians/gynecologists, and other providers need to be knowledgeable about and comfortable using genetic information to improve their patients' health. To address these changes, the Roundtable on Translating Genomic-Based Research for Health held the public workshop "Innovations in Service Delivery in the Age of Genomics" on July 27, 2008.

Medical and Health Genomics

2016-06-04 Science
Download Medical and Health Genomics PDF Online Free

Author :
Release : 2016-06-04
Genre : Science
Kind : eBook
Book Rating : 221/5 ( reviews)

GET EBOOK


Book Synopsis Medical and Health Genomics by : Dhavendra Kumar

Download or read book Medical and Health Genomics written by Dhavendra Kumar. This book was released on 2016-06-04. Available in PDF, EPUB and Kindle. Book excerpt: Medical and Health Genomics provides concise and evidence-based technical and practical information on the applied and translational aspects of genome sciences and the technologies related to non-clinical medicine and public health. Coverage is based on evolving paradigms of genomic medicine—in particular, the relation to public and population health genomics now being rapidly incorporated in health management and administration, with further implications for clinical population and disease management. Provides extensive coverage of the emergent field of health genomics and its huge relevance to healthcare management Presents user-friendly language accompanied by explanatory diagrams, figures, and many references for further study Covers the applied, but non-clinical, sciences across disease discovery, genetic analysis, genetic screening, and prevention and management Details the impact of clinical genomics across a diverse array of public and community health issues, and within a variety of global healthcare systems

You may also like...