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Single Cell Diagnostics

2008-02-02 Science
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Release : 2008-02-02
Genre : Science
Kind : eBook
Book Rating : 98X/5 ( reviews)

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Book Synopsis Single Cell Diagnostics by : Alan R. Thornhill

Download or read book Single Cell Diagnostics written by Alan R. Thornhill. This book was released on 2008-02-02. Available in PDF, EPUB and Kindle. Book excerpt: This book applies modern molecular diagnostic techniques to the analysis of single cells, small numbers of cells, or cell extracts. Emphasis is placed on non-invasive analysis of single cell metabolites and the direct analysis of RNA and DNA from single cells, with a focus on polymerase chain reaction and fluorescence in situ hybridization. In particular, this handbook is essential for practitioners providing care for couples seeking treatment for infertility.

Single Cell Analysis

2021-06-02 Science
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Release : 2021-06-02
Genre : Science
Kind : eBook
Book Rating : 284/5 ( reviews)

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Book Synopsis Single Cell Analysis by : Tuhin Subhra Santra

Download or read book Single Cell Analysis written by Tuhin Subhra Santra. This book was released on 2021-06-02. Available in PDF, EPUB and Kindle. Book excerpt: Cells are the most fundamental building block of all living organisms. The investigation of any type of disease mechanism and its progression still remains challenging due to cellular heterogeneity characteristics and physiological state of cells in a given population. The bulk measurement of millions of cells together can provide some general information on cells, but it cannot evolve the cellular heterogeneity and molecular dynamics in a certain cell population. Compared to this bulk or the average measurement of a large number of cells together, single-cell analysis can provide detailed information on each cell, which could assist in developing an understanding of the specific biological context of cells, such as tumor progression or issues around stem cells. Single-cell omics can provide valuable information about functional mutation and a copy number of variations of cells. Information from single-cell investigations can help to produce a better understanding of intracellular interactions and environmental responses of cellular organelles, which can be beneficial for therapeutics development and diagnostics purposes. This Special Issue is inviting articles related to single-cell analysis and its advantages, limitations, and future prospects regarding health benefits.

Experimental and Computational Tools for Single Cell Analysis in Cancer Diagnostics

2020
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Release : 2020
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Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Experimental and Computational Tools for Single Cell Analysis in Cancer Diagnostics by : Manibarathi Vaithiyanathan

Download or read book Experimental and Computational Tools for Single Cell Analysis in Cancer Diagnostics written by Manibarathi Vaithiyanathan. This book was released on 2020. Available in PDF, EPUB and Kindle. Book excerpt:

Single-Cell Omics

2019-07-31
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Release : 2019-07-31
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Kind : eBook
Book Rating : 32X/5 ( reviews)

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Book Synopsis Single-Cell Omics by : Debmalya Barh

Download or read book Single-Cell Omics written by Debmalya Barh. This book was released on 2019-07-31. Available in PDF, EPUB and Kindle. Book excerpt: Single-cell Omics, Volume 2: Advances in Applications provides the latest single-cell omics applications in the field of biomedicine. The advent of omics technologies have enabled us to identify the differences between cell types and subpopulations at the level of the genome, proteome, transcriptome, epigenome, and in several other fields of omics. The book is divided into two sections: the first is dedicated to biomedical applications, such as cell diagnostics, non-invasive prenatal testing (NIPT), circulating tumor cells, breast cancer, gliomas, nervous systems and autoimmune disorders, and more. The second focuses on cell omics in plants, discussing micro algal and single cell omics, and more. This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and several members of biomedical field interested in understanding more about single-cell omics and its potential for research and diagnosis. Covers the diverse single cell omics applications in the biomedical field Summarizes the latest progress in single cell omics and discusses potential future developments for research and diagnosis Written by experts across the world, it brings different points-of-view and study cases to fully give a comprehensive overview of the topic

Single-cell Sequencing and Methylation

2020-10-14 Science
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Release : 2020-10-14
Genre : Science
Kind : eBook
Book Rating : 934/5 ( reviews)

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Book Synopsis Single-cell Sequencing and Methylation by : Buwei Yu

Download or read book Single-cell Sequencing and Methylation written by Buwei Yu. This book was released on 2020-10-14. Available in PDF, EPUB and Kindle. Book excerpt: With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients.

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