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Signal Transduction by Reactive Oxygen and Nitrogen Species: Pathways and Chemical Principles

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Release : 2006-02-17
Genre : Science
Kind : eBook
Book Rating : 129/5 ( reviews)

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Book Synopsis Signal Transduction by Reactive Oxygen and Nitrogen Species: Pathways and Chemical Principles by : H.J. Forman

Download or read book Signal Transduction by Reactive Oxygen and Nitrogen Species: Pathways and Chemical Principles written by H.J. Forman. This book was released on 2006-02-17. Available in PDF, EPUB and Kindle. Book excerpt: Henry Jay Forman, Jon Fukuto and Martine Torres "Research is to see what everybody else has seen and to think what nobody else has thought. " -- Albert Szent-Gyorgyi Several years ago, one of us put together a book that dealt with various aspects of oxidative stress and introduced the concept of signal transduction by oxidants. Since then, the interest in the mechanisms by which reactive oxygen and nitrogen species (ROS/RNS) can modulate the cell’s response has tremendously grown, paralleling the intense efforts towards identifying new signaling pathways in which phosphorylation/dephosphorylation events take center stage. Evidence is now mounting that production of these species by the cells is required for their function from growth to apoptosis and numerous signaling pathways have been identified where the participation of ROS and RNS is apparent (see Chapters 11-14, 16 and 18). Thus, the field is no more limited to the group of free radical aficionados who have pioneered this area of research but has now gone mainstream. While it is satisfactory for those of us who have been working on this topic for a long time, it has the risk of becoming the “fashionable” motto where those molecules, still mysterious to some, become responsible for everything and anything.

Signaling Mechanisms of Oxygen and Nitrogen Free Radicals

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Release : 2009-06-18
Genre : Medical
Kind : eBook
Book Rating : 753/5 ( reviews)

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Book Synopsis Signaling Mechanisms of Oxygen and Nitrogen Free Radicals by : Igor B. Afanas'ev

Download or read book Signaling Mechanisms of Oxygen and Nitrogen Free Radicals written by Igor B. Afanas'ev. This book was released on 2009-06-18. Available in PDF, EPUB and Kindle. Book excerpt: Once the existence of free radicals was proven, an avalanche of studies on free radical-mediated biological processes ensued. The study of reactive oxygen and nitrogen species (ROS and RNS) is center stage in biological free radical investigations. Written by a biochemist, Signaling Mechanisms of Oxygen and Nitrogen Free Radicals discusses the regu

Sturkie's Avian Physiology

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Release : 2021-11-06
Genre : Science
Kind : eBook
Book Rating : 51X/5 ( reviews)

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Book Synopsis Sturkie's Avian Physiology by : Colin G. Scanes

Download or read book Sturkie's Avian Physiology written by Colin G. Scanes. This book was released on 2021-11-06. Available in PDF, EPUB and Kindle. Book excerpt: Sturkie's Avian Physiology, Seventh Edition is the classic comprehensive single volume on the physiology of domestic as well as wild birds. This latest edition is thoroughly revised and updated and features several new chapters with entirely new content on such topics as vision, sensory taste, pain reception, evolution, and domestication. Chapters throughout have been greatly expanded due to the many recent advances in the field. This book is written by international experts in different aspects of avian physiology. For easy reading and searches, this book is structured under a series of themes, beginning with genomic studies, sensory biology and nervous systems, and major organs. The chapters then move on to investigate metabolism, endocrine physiology, reproduction, and finally cross-cutting themes such as stress and rhythms. New chapters on feathers and skin are featured as well. Sturkie’s Avian Physiology, Seventh Edition is an important resource for ornithologists, poultry scientists, and other researchers in avian studies. It is also useful for students in avian or poultry physiology, as well as avian veterinarians. Stands out as the only single volume devoted to bird physiology Features updates, revisions, or additions to each chapter Written and edited by international leaders in avian studies

Feed Efficiency in the Beef Industry

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Release : 2012-06-18
Genre : Science
Kind : eBook
Book Rating : 240/5 ( reviews)

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Book Synopsis Feed Efficiency in the Beef Industry by : Rodney A. Hill

Download or read book Feed Efficiency in the Beef Industry written by Rodney A. Hill. This book was released on 2012-06-18. Available in PDF, EPUB and Kindle. Book excerpt: Feed Efficiency in the Beef Industry provides a thorough and concise overview of feed efficiency in beef cattle. It frames the great importance of feed efficiency to the industry and details the latest findings of the many scientific disciplines that intersect and aim to improve efficient and sustainable production of nutritious beef. The vast majority of production costs are directly tied to feed. With increased demand for grains to feed a rapidly increasing world population and to supply a new demand for alternative fuels, feed costs continue to increase. In recent years, the negative environmental impacts of inefficient feeding have also been realized; as such feed efficiency is an important factor in both economic viability and environmental sustainability of cattle production. Feed Efficiency in the Beef Industry covers a broad range of topics ranging from economic evaluation of feed efficiency to the physiological and genetic bases of efficient conversion of feed to high quality beef. Chapters also look at how a fuller understanding of feed efficiency is leading to new selective breeding efforts to develop more efficient cattle. With wide-ranging coverage from leading international researchers, Feed Efficiency will be a valuable resource for producers who wish to understand the complexities, challenges, and opportunities to reduce their cost of production, for students studying the topic and for researchers and professionals working in the beef industry.

Studies on Men's Health and Fertility

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Release : 2012-03-17
Genre : Science
Kind : eBook
Book Rating : 758/5 ( reviews)

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Book Synopsis Studies on Men's Health and Fertility by : Ashok Agarwal

Download or read book Studies on Men's Health and Fertility written by Ashok Agarwal. This book was released on 2012-03-17. Available in PDF, EPUB and Kindle. Book excerpt: Studies on Men’s Health and Fertility provides a comprehensive series of up-to-the-minute reviews addressing the role of oxidative stress in the aetiology of reproductive pathologies in the male. This volume represents by far the most detailed, authoritative review of the field that has been produced to date. The text encompasses the basic science of reactive oxygen species (ROS) production by mammalian spermatozoa, the way in which these highly reactive molecules are processed by the germ line and the physiological significance of this redox activity in the generation of a functional gamete. The factors responsible for perturbing the delicate balance between physiological redox signaling on the one hand and oxidative stress on the other are also extensively reviewed and some of the first clues concerning the underlying mechanisms (age, heat, infection, cryostorage, aberrant lipid metabolism), clearly identified. From a clinical perspective there are chapters setting out the methods we should be using to diagnose oxidative stress in the male germ line, a clinical perspective on the aetiology of this condition and detailed considerations of the most suitable means of ameliorating such stress from a therapeutic point of view. Studies on Men’s Health and Fertility is intended to provide clinicians and scientists with a snap shot of the current status of this exciting, rapidly moving field. The book will be of value to clinicians interested in strategies for the management of oxidative stress in their infertility patients and scientists wishing to understand the molecular mechanisms underpinning the generation of ROS by these cells and its pathophysiological significance. It was not so long ago that the ability of spermatozoa to generate ROS was a hotly disputed topic. With the publication of this book such doubts can finally be laid to rest. There is now no doubt that these cells actively generate ROS, that oxidative stress is a major contributor to defects in male reproductive health and that the successful clinical management of this condition depends on developing a deeper understanding of the underlying molecular mechanisms. In this quest, Studies on Men’s Health and Fertility will be seen as a clear and important milestone.

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