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Serpin Structure and Evolution

2011-11-16 Medical
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Release : 2011-11-16
Genre : Medical
Kind : eBook
Book Rating : 506/5 ( reviews)

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Book Synopsis Serpin Structure and Evolution by : James Whisstock

Download or read book Serpin Structure and Evolution written by James Whisstock. This book was released on 2011-11-16. Available in PDF, EPUB and Kindle. Book excerpt: Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. This volume in the Methods in Enzymology series comprehensively covers this topic. With an international board of authors, this volume covers subjects such as Crystallography of serpins and serpin complexes, Serpins as hormone transporters, and Production of serpins using cell free systems. This volume in the Methods in Enzymology series comprehensively covers the topic of serpins With an international board of authors, this volume covers subjects such as Crystallography of serpins and serpin complexes, Serpins as hormone transporters, and Production of serpins using cell free systems

Biology of Serpins

2011-06-11 Science
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Release : 2011-06-11
Genre : Science
Kind : eBook
Book Rating : 720/5 ( reviews)

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Book Synopsis Biology of Serpins by : James Whisstock

Download or read book Biology of Serpins written by James Whisstock. This book was released on 2011-06-11. Available in PDF, EPUB and Kindle. Book excerpt: Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. This volume of Methods in Ezymology is split into 2 parts and comprehensively covers the subject.

Chemistry and Biology of Serpins

2012-12-06 Science
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Release : 2012-12-06
Genre : Science
Kind : eBook
Book Rating : 911/5 ( reviews)

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Book Synopsis Chemistry and Biology of Serpins by : Frank C. Church

Download or read book Chemistry and Biology of Serpins written by Frank C. Church. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of an International Symposium held in Chapel Hill, North Carolina, April 13-16, 1996

Serpin Structure and Evolution

2011-11-07 Science
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Release : 2011-11-07
Genre : Science
Kind : eBook
Book Rating : 514/5 ( reviews)

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Book Synopsis Serpin Structure and Evolution by :

Download or read book Serpin Structure and Evolution written by . This book was released on 2011-11-07. Available in PDF, EPUB and Kindle. Book excerpt: Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. This volume in the Methods in Enzymology series comprehensively covers this topic. With an international board of authors, this volume covers subjects such as Crystallography of serpins and serpin complexes, Serpins as hormone transporters, and Production of serpins using cell free systems. - This volume in the Methods in Enzymology series comprehensively covers the topic of serpins - With an international board of authors, this volume covers subjects such as Crystallography of serpins and serpin complexes, Serpins as hormone transporters, and Production of serpins using cell free systems

Molecular and Cellular Aspects of the Serpinopathies and Disorders in Serpin Activity

2007 Medical
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Release : 2007
Genre : Medical
Kind : eBook
Book Rating : 549/5 ( reviews)

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Book Synopsis Molecular and Cellular Aspects of the Serpinopathies and Disorders in Serpin Activity by : Gary A. Silverman

Download or read book Molecular and Cellular Aspects of the Serpinopathies and Disorders in Serpin Activity written by Gary A. Silverman. This book was released on 2007. Available in PDF, EPUB and Kindle. Book excerpt: Serpins constitute a superfamily of proteins that possess a unique tertiary structure and mechanism of proteinase inhibition. In humans, serpins constitute 10% of the plasma proteins and are best known as critical regulators of both the thrombotic and fibrinolytic systems. Serpins also participate in the regulation of the complement cascade, angiogenesis, tumor metastasis, apoptosis and innate immunity. Considering the importance of these molecules in regulating proteolytic cascades, it is not surprising to find that loss- and gain-of-function mutations result in significant human diseases. Massive thrombosis or bleeding, hereditary angioedema, Alzheimer''s disease, diabetic angiopathy and tumor invasion are some of the human diseases associated with serpins. In addition, mutations that alter serpin conformations (the serpinopathies) lead to lung disease, cirrhosis and a form of familial dementia. The goal of this text is to present the current knowledge on the molecular and cellular basis of serpins and their diseases.

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